Researchon Ionized Waterand Wound Healing
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Electrolyzed water from the anode chamber of electrolysis, whether acidic or neutralized, accelerated healing of full-thickness skin wounds in rats, while hypochlorous acid and cathode chamber water did not. Reactive oxygen species present in anode chamber water may enhance early wound healing through stimulation of fibroblast migration and proliferation, rather than through hypochlorous acid's antibacterial effects.
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- 1. Effect of electrolyzed water on wound healing ARTIFICIAL ORGANS. 2000 Dec; 24(12):984-7 Yahagi N, Kono M, Kitahara M, Ohmura A, Sumita O, Hashimoto T, Hori K, Ning-Juan C, Woodson P, Kubota S, Murakami A, Takamoto S Department of Anesthesiology, Teikyo University Mizonokuchi Hospital, Tokyo, Japan. Electrolyzed water accelerated the healing of full-thickness cutaneous wounds in rats, but only anode chamber water (acid pH or neutralized) was effective. Hypochlorous acid (HOCl), also produced by electrolysis, was ineffective, suggesting that these types of electrolyzed water enhance wound healing by a mechanism unrelated to the well-known antibacterial action of HOCl. One possibility is that reactive oxygen species, shown to be electron spin resonance spectra present in anode chamber water, might trigger early wound healing through fibroblast migration and proliferation.