Proteases are enzymes that break down proteins into smaller polypeptides or amino acids through proteolysis. They serve several important functions including protein digestion, blood coagulation, cell growth and apoptosis, immune response, and wound healing. Proteases can be derived from plants, microorganisms, and animals and are classified based on their reaction type, site of enzyme action, pH level, and catalytic mechanism. They have applications in industries like food processing, detergents, pharmaceuticals, and waste management.

1. “PROTEASE ENZYME”
By
SyedaSadafWajahat

2. What are Proteases?
▪ Proteases are the enzymes which breakdown
the proteins into smaller polypeptides or amino
acids (proteolysis).
▪ Proteases, as also known as as peptidases or
proteinases.

3. Functions of
Proteases
• Digestion and catabolism of proteins.
• Blood coagulation.
• Cell division, growth, apoptosis and migration.
• Protein recycling and transport across membranes.
• Mediate immune response.
• Wound healing and muscle soreness.
• Video:
https://www.youtube.com/watch?v=DvqZea4dq5E

4. Sources of Proteases
Sources
Plants
(e.g. Papain,
Bromelain)
Microorganisms
(e.g. Subtilisin,
Thermolysin)
Animals
(e.g. Trypsin,
Pepsin)

5. Classification of Proteases

6. On the basis of
reaction they catalyze

8. On the basis of site of enzyme
action

10. On the basis of pH

11. pH
Acidic
Alkaline
Neutral

12. On the basis of mechanism of
catalysis

13. Threonine
peptidase
Asparagine
peptidase
Aspartic
peptidase
Cysteine
peptidase
Glutamic
peptidase
Metallo-
peptidase
Serine
peptidase

14. Applications of Proteases