Pliny's Natural History discusses various types of marble used in ancient Rome for sculpture, architecture, and medicine. It describes the marble quarries and trade routes that supplied marble throughout the Roman Empire for prominent buildings like the Porticus Octaviae in Rome. Marble was also used to craft famous sculptures such as the Venus of Cnidus and reconstructions of Phidias' Olympian Zeus and Athena Parthenos. The text also explores how architecture reflected political changes in Rome and examines the use of various stones and minerals for medical purposes in the 1st century.