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Using literature mining to 
explore concept complexity in 
obesity
George Karystianis
School of Computer Science 
Supervisors
Goran Nenadic, Iain Buchan
2
Obesity (1)
●
  Complex/underlying epidemic
●
 Worldwide problem
●
 Related to various diseases
●
 Various aspects
Obesity (2)
Obesity concept map
5
Motivation and Aim
●
Assist clinicians/researchers in representation                 
  and validation of their knowledge.
­ Assist in health care improvement.
●
 Exploration of medical knowledge.
●
 Enhance the understanding of the health concepts in      
  obesity.
●
 Design a framework for generation (or improvement of  
   existing) of medical concept maps.
6
Objectives
●
To generate a set of methods to detect obesity related 
concepts in literature.
●
To validate obesity information.
– discover any significant differences in the 
understanding of the disease.
●
To integrate data and literature.
–  discover new knowledge related to obesity.
●
To provide and evaluate a framework for         
building and validation of medical concept maps.
7
Text mining 
●
 Extraction of information from unstructured data.
●
 Performed on documents with complex and specific       
  terminology and expressions.
●
 Challenges: 
­Ambiguity, Synonyms, fuzzy conclusions.
●
 Various tools and applications available.
●
 Adaptation to user's and task needs.
8
Concept Maps
●
 Knowledge representation model.
●
 Constructed by concepts and links.
●
 Gather, understand, explore knowledge.
●
 Variety of users.
●
 No explicit detail.
●
 Implementations mainly in education.
9
Overview of the project
Medical
literature
Epidemiological
data
Text mining
techniques
Concept
map
Validation
Enhancement
Results
Improved
Concept map
What are we looking for?
– Risk factors
– Causal factors
– Confounding factors
– Complications
– Interventions
– Outcomes (primary, secondary)
– Exposures
11
Example
12
Methodology overview (1)
PubMed
Obesity
Literature
Analysis
Semantic
Analysis
Triggers
Set of rules
Information
Extraction
Engine
Results
Modelling
13
Methodology overview (2)
Information
Extraction
Engine
Term
recognition
Term
structuring
Pattern
matching
Important
terms
Patterns
Terminology
heads
Term
class
Terminology identification Pattern recongition
14
Results
15
Evaluation
●
 Compare the results from the use of text mining             
  methods with the concept map ones.
●
 Are these terms: 
 a) important?
 b) related to obesity? 
 c) common?
●
 Examination and classification of the new concepts/       
  links through experts. 
­Validation/enhancement of the concept map.
16
Summary
Use Text Mining methods to:
●
 Extract risk, causal factors, complications, etc.
●
 obtain a better understanding of obesity concepts.
●
 provide a framework for building of medical concept      
  maps. 
17
Thank you for attending and  for listening.

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