4. 2)BULK POWDER(UNDIVIDED POWDER)
These are powders used for less potent drugs. These are
powders supplied in bulk or large quantities. They are
intended for internal or external use.
ā¢DUSTING POWDER
ā¢EFFERVESCENT POWDER
ā¢ANTACIDS,LAXATIVES AND DIETARY SUPPLIMENTS
5. PREPARATION OF
PHARMACEUTICAL POWDER
Reduction of particle size particle size of all
ingredient to the same range to prevent
stratification
Sieving
Weighing of each ingredient
Mixing
Packaging
6. ADVANTAGES OF PHARMACUETICAL
POWDERS
ļ± Powders are more stable than liquid dosage form.
ļ± Useful for bulky drugs with large dose.
ļ± Example:Indigestion Powder
ļ± Easy to swallow even in large bulk especially when mixed with drink
food(useful for stomach-tubefeeding)
ļ± The smaller particle size of powders causes more rapid dissolution in body
fluids,druf bioavailability and decrease gastric irritation compare with tablets.
7. DISADVANTAGES OF PHARMACEUTICAL
POWDERS
ļ± Time consuming preparation.
ļ± Inaccuracy of dose(Size of measuring spoon, density of
powder,humidity,degree of settling).
ļ± Unsuitablity of many unpleasant tasting hygroscopic and
deliquescent.
ļ± Patient may misunderstand the correct method of use without clear
instructions.ie Patient may inhale through the nose intended for oral
administration.
8. CONCLUSION
ļ Powder dosage form are versatile flexible in a dosage
strength relatively stable and also convenient to
manufacture,store,handle and use.
ļ It is possible to reduce than to desired particle size
and thus facilitate rapid absorption.Thus from
biopharmaceutical consideration powder are
convenient and useful for prescribing drug.
ļ Power flow is also crucial during mixing,packaging
and transportation.
ļ Reduction in process cost and maintaining the
quality and consistency of the final product.
9. *REFERENCES
BOOKS
I. COOPER AND GUNNāS
TUTORIAL
II. MARTIN PHYSICAL
PHARMACY
III. AAPāS INTRODUCTION
IN PHARMACEUTICAL
SCIENCES
WEBSITES
1. www.pharmlabs.unc.edu
2. www.pharmapproach.co
m/pharmaceutical-
powder-an-overview/THANK YOU