This document appears to describe a series of oral pathological cases presented to dentists or oral medicine specialists. Each case provides brief information about a patient's symptoms, medical history, and initial findings or diagnosis. The cases cover a range of conditions including peripheral giant cell granuloma, cystic ameloblastoma, Langerhans cell disease, carcinoma in situ, ossifying fibroma, mucoepidermoid carcinoma, rhabdomyosarcoma, pemphigus vulgaris, hyperkeratosis with dysplasia, lupus erythematosus, oral candidiasis, odontogenic keratocyst and nevoid basal cell carcinoma syndrome, and Crohn's disease. Photographs

1. َ‫و‬ ِ‫ت‬‫ا‬َ‫او‬َ‫م‬َّ‫س‬‫ال‬ ِ‫ق‬ْ‫ل‬َ‫خ‬ ‫ي‬ِ‫ف‬ َّ‫ن‬ِ‫إ‬ ‫تعالى‬ ‫قال‬ِ‫ف‬ َ‫َل‬ِ‫ت‬ْ‫اخ‬َ‫و‬ ِ‫ض‬ْ‫ر‬َ ْ‫اْل‬
َ ْ‫اْل‬ ‫ي‬ِ‫ل‬‫و‬ُ ِِ‫ْل‬ ٍ‫ت‬‫ا‬َ‫ي‬ َ‫َل‬ ِ‫ار‬َ‫ه‬َّ‫ن‬‫ال‬َ‫و‬ ِ‫ل‬ْ‫ي‬َّ‫ل‬‫ال‬ِ ‫ا‬َ‫ا‬ْ‫ل‬(190)

2. Oral Pathological Cases
Part I

3. Prepared by
Romissaa Aly
Instructor in Oral Medicine, Periodontology, Diagnosis and
Radiology - Al-Azhar University-Girls branch

4. CASE : PERIPHERAL GIANT CELL
GRANULOMA
A 30-year-old female went to her dentist
because of an asymptomatic lump that
she had discovered on her gingiva. She
had no systemic problems and was taking
no medications.

6. Peripheral giant cell granuloma

7. CASE : CYSTIC AMELOBLASTOMA WITH
MURAL INVASION
A 29-year-old male presented because of
a slowly enlarging anterior mandible. The
swelling was noted several weeks after an
auto accident. He had no symptoms.

10. ystic ameloblastoma with mural invasion

11. CASE : LANGERHANS CELL DISEASE
A 42-year-old female was refractory to
periodontal therapy. She had gingival pain and
tooth mobility. Left neck lymphadenopathy
was present. She has a history of aphthous
ulcers.

15. CD1a stain
Langerhans cell disease

16. CASE : LANGERHANS CELL DISEASE
A 4-year-old female developed pain in her
left mandible that was exacerbated with
chewing. There was no associated
paresthesia or deformity. Head and neck
exam was otherwise within normal limits.
CBC was normal.

18. CD1a stain

19. CD68 stain

20. Humerus

21. Langerhans cell disease

22. CASE : CARCINOMA IN SITU
On routine exam, a lesion was found in
the floor of the mouth of a 55-year-old
female. She had no symptoms and was in
good health. She did not smoke or drink
alcohol. She took no medications.

25. Recurrence stained with toluidine blue

27. CASE : OSSIFYING FIBROMA
On routine radiographic exam, a lesion was
noted in this 22-year-old male. It caused no
symptoms and was of unknown duration. The
jaw cortex was not expanded.

30. Ossifying fibroma

31. CASE : OSSIFYING FIBROMA
A 17-year-old male presented with a
persistent swelling of his jaw of several
months’ duration. He had no associated pain
or paresthesia. He had no history of jaw
infection or trauma. His systemic health was
excellent. All teeth tested vital.

34. Ossifying fibroma

35. CASE : MUCOEPIDERMOID CARCINOMA,
LOW-GRADE
A 33-year-old female became aware of a
slightly painful lesion in the posterior-lateral
aspect of her tongue. She had no history of
trauma. She did not smoke or drink alcohol,
and she was 6-months pregnant.

38. Mucoepidermoid carcinoma
Low-grade

39. CASE : MALIGNANT NEOPLASM
CONSISTENT WITH
RHABDOMYOSARCOMA
A 19-year-old male went to his dentist because
“his bite was off.” His upper lip was also numb for
the past three weeks. He had no history of trauma,
facial pain, diplopia, epiphora, or epistaxis. Prior to
the development of his chief complaint, he was in
excellent health.

43. Malignant neoplasm
c/w rhabdomyosarcoma

44. CASE: PEMPHIGUS VULGARIS
A 45-year-old factory worker was seen because
of severe sore mouth and sore throat of 4-month’s
duration. Treatment with penicillin, nystatin, and
vitamin C were ineffective. The patient had “colitis”
three years ago which was apparently under
medical control.

48. Pemphigus vulgaris

49. CASE : PEMPHIGUS VULGARIS
A 45-year-old male developed a sore mouth after
eating fish. His oral pain has been continuous for 2
months. He had no history of eye, genital, or skin
lesion. He had no systemic problems. He was
given symptomatic treatment and was asked to
return in 2 weeks.

53. Pemphigus vulgaris

54. CASE 10: HYPERKERATOSIS WITH
DYSPLASIA
During routine exam of a 34-year-old male, a
lesion was discovered in the floor of his mouth. He
was unaware of the lesion. He did not smoke and
was a “light drinker.” He had no history of an
associated traumatic event or habit that might
result in irritation to the area.

56. Hyperkeratosis with dysplasia

57. CASE : LUPUS ERYTHEMATOSUS
A 62-year-old female presented with oral
lesions of 7 years’ duration. Pain had been
increasing in intensity (moderate to severe).
She also had scaly red lesions on her face.
Her medications included Lopressor and
Valium. She was allergic to wool.

62. CASE :ORAL CANDIDIASIS
A 31-year-old dental hygiene student
developed a sore throat during final
exams. Other than being under stress,
she felt well. She had no systemic
problems and was taking no medications.

64. Candidiasis
Cytology

65. CASE : ODONTOGENIC KERATOCYST AND NEVOID
BASAL CELL CARCINOMA SYNDROME
An 8-year-old male presented with unilateral
mandibular expansion. He had no associated
pain or paresthesia. His systemic health was
otherwise excellent.

69. Father

70. Odontogenic keratocyst

71. CASE : CROHN’S DISEASE
A 17-year-old male sought treatment for persistent
oral pain. He had the problem for several weeks
and believed that it was getting worse. He was
treated with a topical corticosteroid, but there was
little improvement. He also complained of fatigue
and occasional abdominal discomfort. He had a
recent weight loss and a low-grade fever.

77. Crohn’s disease

78. Referance:
Oral pathology: Clinical pathologic
correlations, 5th ed Joseph A.
Regezi, James J. Sciubba, and
Richard C. K. Jordan. St. Louis:
Saunders Elsevier. 2007.

79. Thank you