1. Molecular and Cellular Biochemistry
April 1993, Volume 121, Issue 1, pp 1–4
Parathyroid hormone in urinary stone
patients
 Authors
 Authors and affiliations
 Aziza Khanam
 M. Ataur Rahman
Article
Received:
18 March 1992
Accepted:
08 September 1992
DOI: 10.1007/BF00928693
Cite this article as:
Khanam, A. & Rahman, M.A. Mol Cell Biochem (1993) 121: 1.
doi:10.1007/BF00928693
 1Citations
 15Downloads
Abstract
To evaluate the role of parathyroids in calculus disease, the parathyroid hormone levels were
determined in 22 control subjects and 42 stone (14 with bladder stone and 28 with kidney stone)
patients. Serum calcium, inorganic phosphate, alkaline phosphatase and parathyroid hormone
and urinary excretion of calcium and inorganic phosphate were determined. It was found that
normocalcemic and normocalciuric stone patients had slightly higher levelsss of parathyroid
hormone (irrespective of the site of the stone) and the difference was not statistically significant
as compared with control subjects although some of the patients with calculus disease were
hyperparathyroid. Serum alkaline phosphatase was increased while there was an increase in
urinary calcium excretion in kidney stone patients and oxalate in all patients as compared with
control subjects. The increase in inorganic phosphate was, however, not different from the
control subjects. The subclinical hyperparathyroidism and stone formation in these patients are
not correlated.