This is the short title Page nr. 1 of 4 
This is the title of the manuscript 
Jos AE Spaan*, Ruben Coronel# 
*Dept of Biomedical Engineering and Physics, Academic Medical Center, 
University of Amsterdam, Meibergreef 7, 1105AZ Amsterdam 
#Dept of Experimental Cardiology, Heart Failure Center, Academic Medical 
Center, University of Amsterdam, Meibergreef 7, 1105AZ Amsterdam 
Corresponding Author: 
Jos AE Spaan, 
e-mail: j.a.spaan@amc.uva.nl 
tel: +31205665202 
fax: +3120xxxxxx 
The total number of words of the manuscript, including entire text from title page to figure 
legends: 5050 
The number of words of the abstract: 199 
The number of figures: 7 
The number of tables: 2 
1
This is the short title Page nr. 2 of 4 
Abstract should not be more than 200 words. Start with aim, describe the method, provide major 
results and provide conclusion 
Coronary circulation, heart, microspheres 
Glossary of terms when relevant 
2
This is the short title Page nr. 3 of 4 
Introduction 
Provide a description of the aims of the manuscript. Try to stay within 1.5 A4 
page. 
Methods 
Patients 
Instrumentation 
Statistics 
Results 
As shown in figure 1 
Discussion 
From this manuscript we may conclude in about three sentences 
3

manuscript

  • 1.
    This is theshort title Page nr. 1 of 4 This is the title of the manuscript Jos AE Spaan*, Ruben Coronel# *Dept of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, Meibergreef 7, 1105AZ Amsterdam #Dept of Experimental Cardiology, Heart Failure Center, Academic Medical Center, University of Amsterdam, Meibergreef 7, 1105AZ Amsterdam Corresponding Author: Jos AE Spaan, e-mail: j.a.spaan@amc.uva.nl tel: +31205665202 fax: +3120xxxxxx The total number of words of the manuscript, including entire text from title page to figure legends: 5050 The number of words of the abstract: 199 The number of figures: 7 The number of tables: 2 1
  • 2.
    This is theshort title Page nr. 2 of 4 Abstract should not be more than 200 words. Start with aim, describe the method, provide major results and provide conclusion Coronary circulation, heart, microspheres Glossary of terms when relevant 2
  • 3.
    This is theshort title Page nr. 3 of 4 Introduction Provide a description of the aims of the manuscript. Try to stay within 1.5 A4 page. Methods Patients Instrumentation Statistics Results As shown in figure 1 Discussion From this manuscript we may conclude in about three sentences 3