This document discusses treatment planning and delivery for multiple lung tumors using single isocenter stereotactic body radiation therapy (SBRT). It notes that using a single isocenter can reduce treatment time but presents challenges due to independent tumor motion. Factors like inter-tumor distance and attachment to pleura that influence relative position change are examined. Tradeoffs between single and multiple isocenter techniques are also considered.

1. Tumors
Infographics
Here is where this template begins

2. Objectifs d'apprentissage
Traitement des
lésions pulmonaires
multiples
• Variation de
position inter
lésionnelle
• Le setup de
patient
• Le dosimetry de
traitement

3. Mouvement différentiel de la
tumeur pulmonaire

4. Traitement avec
plusieurs isocentres
Traite ment avec un seul
isocentre
• Un isocenter pour chaque
lesion cible
• Plusieurs CBCT s pendant le
traitement / seance
• si les cibles se déplacent
différemment, la somme des
doses changera
• Temps de traitement longs
• Un seul isocentre pour tous
lesions
• Un seul CBCT pendant le
traitement
• éviter les chevauchements
OVERLAP de doses
involontaires
• réduction de la planification et
du temps de traitement global

5. Difficultes pour le
single isocenter plan
• Augumentation de
margins? Pour le
single iso center
technique
• Pour le technique a
plusieurs isocentres le
dose peut etre
augumenter ou
diminuer en raison du
movement relative (et
alignment) de la cible

7. Variation relative de la position omter lesionelle
Magnitude de la 3D vecteur
3D vecteur de movement < median
3D vecteur de movement > median
cinq valeurs aberrantes présentant de grands déplacements

8. Variation relative de la position omter lesionelle
Influence de la localization de la lesion
• Attache a la pleura?
• Les deux dans le meme poumon
• Les deux dans le meme lobe
• Distance entre les lesions
• Une lesion non attache et
distance > median
• Une lesion non attache et
distance < median
• Les deux lesions attachees

9. Tumors infographics
Surgery
Mercury is the closest
planet to the Sun and
the smallest one in the
entire Solar System
A
Chemotherapy
Venus has a very
beautiful name but is
actually terribly hot,
hotter than Mercury
B
Immunotherapy
Jupiter is a huge gas
giant named after the
Roman god of the skies
and lightning
C

18. Conclusions
Chemotherapy
Venus has a very
beautiful name but is
actually terribly hot,
hotter than Mercury
B
Immunotherapy
Jupiter is a huge gas
giant named after the
Roman god of the skies
and lightning
C

19. Week 4
✓ Venus has a beautiful
name but is very hot
✓ Saturn is a gas giant and
has several rings
Week 5
✓ Uranus is the seventh
planet from the Sun
✓ The Sun is the star at
the Solar System
Week 6
✓ Ceres is located in the
main asteroid belt
✓ The Moon is a natural
satellite of planet Earth
Tumors infographics
Week 1
✓ Jupiter is a gas giant
and the biggest planet
✓ Mercury is the closest
planet to the Sun
Week 2
✓ Neptune is the farthest
planet from the Sun
✓ Despite being red, Mars
is a cold place
Week 3
✓ Pluto is considered a
dwarf planet
✓ Earth is the third planet
from the Sun

20. Tumors infographics
Surgery
Mercury is the closest
planet to the Sun and
the smallest one in the
entire Solar System
A
Chemotherapy
Venus has a very
beautiful name but is
actually terribly hot,
hotter than Mercury
B
Immunotherapy
Jupiter is a huge gas
giant named after the
Roman god of the skies
and lightning
C

21. Tumors infographics
Exercice
Mercury is the closest
planet to the Sun
Smoke
Despite being red, Mars
is a cold place
Healthy diet
Venus has a beautiful
name but is hot
Stress
Pluto is considered a
dwarf planet
Sleep well
Earth is the third planet
from the Sun
Eat junk food
Ceres is located in the
main asteroid belt
Do’s & don’ts

23. Using a single isocenter for multiple targets in combination
with intensity-modulated radiotherapy (IMRT), or volumetric
modulated arc therapy (VMAT), recently gained interest. It may
result in a more efficient workflow, reduce the number of monitor
units (MU) and thereby reduce the cumulative patient dose, overall
planning/treatment time, and improve cost-effectiveness [5–10].
However, a major challenge in lung SBRT as opposed to intracranial
single-isocenter treatments, is that different parts of the lung are
known to move independently, and the inter-target distance may
vary on a day-to-day basis [11]. Therefore, the possibility that
multiple
targets move and rotate relative to each other has to be taken

26. 50%
75%
25%
Jupiter
Jupiter is a gas
giant and the
biggest planet
02
Mars
Despite being
red, Mars is a
very cold place
03
Mercury
Mercury is the
closest planet
to the Sun
01
Success rate
Objectifs d'apprentissage
traitement des lésions pulmonaires multiples

27. 105K
Survivors
112K
Survivors
Tumors infographics
Mercury
Mercury is the closest
planet to the Sun and
the smallest one in the
entire Solar System
Venus
Venus has a very
beautiful name but is
actually terribly hot,
hotter than Mercury
Jupiter
Jupiter is a huge gas
giant named after the
Roman god of the skies
and lightning
154K
Survivors

28. Tumors infographics
Induction
chemotherapy
Mercury is the closest
planet to the Sun
Consolidation
chemotherapy
Despite being red,
Mars is a cold place
Maintenance
chemotherapy
Jupiter is a gas giant
and the biggest planet
Central nervous
system prophylaxis
Neptune is the far
away from Earth
Goal

29. Deaths worldwide
Jupiter is a gas giant
and the biggest planet
7.4 million
Tumors infographics
Leading types of
cancer and
mortality rate
Lung
Mercury is the closest
planet to the Sun
1.3 million
Stomach
Neptune is the farthest
planet from the Sun
803,000
Skin
Despite being red, Mars
is a cold place
340,000
Brain
Pluto is considered a
dwarf planet
650,000

30. Tumors infographics
Chemotherapy
● Nausea
● Weakness
● Fever
Immunotherapy
● Flu symptoms
● Fatigue
● Rush
Radiation therapy
● Nausea
● Fatigue
● Hair loss
Surgery
● Headache
● Fatigue
● Infection risk
Cancer treatments
and side effects

31. Tumors infographics
Prevalence
Tumor
Oesophagus
Jupiter is a gas giant
and the biggest planet
25%
1.5 million Cases
worldwide
Lung
Mercury is the closest
planet to the Sun
15%
1.2 million Cases
worldwide

32. Tumors infographics
Benign
Mercury is the closest planet
to the Sun and the smallest
one in the entire Solar System
Malignant
Saturn is a gas giant and has
several rings. It's composed
mostly of hydrogen and helium
Benign vs.
malignant tumors

33. Tumors infographics
Saturn is a big gas
giant and has several
rings. It's composed
mostly of hydrogen
and also helium
Jupiter
Mercury
01
Mars
02 03
Do’s
Earth is the third
planet from the Sun
and the only one that
harbors life in the
Solar System
Pluto
01
Ceres
02
Neptune
03
Don’ts

34. Tumors infographics
Mars
Despite being red,
Mars is a cold place
01
Jupiter
Jupiter is a gas giant
and the biggest planet
02
Neptune
It’s the farthest planet
from the Sun
03
01
Mercury
Mercury is the closest
planet to the Sun
03
Pluto
Pluto is considered a
dwarf planet
02
Venus
Venus has a beautiful
name but is hot
Malignant
tumor
A
B

35. Tumors infographics
Lung
Mercury is the closest
planet to the Sun
Breast
Despite being red, Mars
is a cold place
Stomach
Venus has a beautiful
name but is hot
Lung
Neptune is the farthest
planet from the Sun
Oesophagus
Jupiter is a gas giant
and the biggest planet
Colorectal
Pluto is considered a
dwarf planet
Prostate
Earth is the third planet
from the Sun
Uterus
Ceres is located in the
main asteroid belt
Frequent types of tumors

36. Tumors infographics
Mars
Despite being
red, Mars is a
very cold place
01
25%
Jupiter
Jupiter is a gas
giant and the
biggest planet
02
45%
Mercury
Mercury is the
closest planet
to the Sun
03
35%
A
B
A Surgery
B Chemotherapy

37. Tumors infographics
Tumor detection
Mercury Saturn Mars Earth Jupiter Venus
Surgery
Mercury is the smallest planet
in the Solar System
Chemotherapy
Despite being red, Mars is a
very cold place
Immunotherapy
Jupiter is a gas giant and the
biggest planet

38. Tumors infographics
Mars
Despite being
red, Mars is a
very cold place
25%
Jupiter
Jupiter is a gas
giant and the
biggest planet
75%
45%
Mercury
55%
Saturn
30%
Neptune
70%
Earth

39. Tumors infographics
Mars
Despite being red, Mars is
a very cold place
01
2/5
Jupiter
Jupiter is a gas giant and
the biggest planet
02
3/5
Neptune
It’s the farthest planet
from the Sun
04
5/5
Mercury
Mercury is the closest
planet to the Sun
03
4/5

40. Tumors infographics
Mercury
Mercury is the closest planet
to the Sun and the smallest
one in the entire Solar System
45%
Saturn
Saturn is a gas giant and has
several rings. It's composed
of hydrogen and helium
55%

41. Tumors infographics
467 million
New
diagnostics
yearly
55%
Localized tumors
Mercury
Mercury is the closest planet
to the Sun and the smallest
one in the entire Solar System
678,367
Patients start the treatment

42. Tumors infographics
Chemotherapy in localized tumors
Lung
Mercury is the closest planet to the
Sun and the smallest one
Brain
Saturn is a gas giant composed
mostly of hydrogen and helium
Skin
Venus has a very beautiful name but
is actually terribly hot
Stomach
Earth is the third planet from the Sun
and the one that harbors life

43. Tumors infographics
Localized
Mercury is the closest
planet to the Sun and
the smallest one in the
entire Solar System
Stage 1 Regional spread
Venus has a very
beautiful name but is
actually terribly hot,
hotter than Mercury
Stage 2 Distant spread
Jupiter is a huge gas
giant named after the
Roman god of the skies
and lightning
Stage 3

44. Tumors infographics
Mercury
Mercury is the
closest planet to
the Sun
Mars
Despite being
red, Mars is a
cold place
Neptune
Neptune is the
farthest planet
from the Sun
Jupiter
Jupiter is a gas
giant and the
biggest planet
Venus
Venus has a
beautiful name
but is hot
180,500
New cases
95,400
Success rate

45. Tumors infographics
Jupiter
Jupiter is a gas giant
and the biggest planet
01
Mercury
Mercury is the closest
planet to the Sun
04
Neptune
Neptune is the farthest
planet from the Sun
02
Mars
Despite being red, Mars
is a cold place
03
Tumor detection
Earth is the third planet
from the Sun and the only
one that harbors life in
the Solar System

46. Tumors infographics
Mercury
Mercury is the closest
planet to the Sun
Jupiter
Jupiter is a gas giant
and the biggest planet
Venus
Venus has a beautiful
name but is hot
Mars
Despite being red, Mars
is a cold place
Neptune
Neptune is the farthest
planet from the Sun

47. Tumors infographics
Mercury
Mercury is the closest
planet to the Sun
Jupiter
Jupiter is a gas giant
and the biggest planet
Venus
Venus has a beautiful
name but is hot
$850 million Earth is the third planet
from the Sun

48. Tumors infographics
Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
320K survivors
Earth is the third planet
from the Sun
Mercury
Mercury is the closest
planet to the Sun
- 50%
Venus
Venus has a beautiful
name but is hot
- 60%
Jupiter
Jupiter is a gas giant
and the biggest planet
- 40%

49. Tumors infographics
Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
Earth
40%
Jupiter
20%
Venus
10%
Mars
30%
Success rate
75%
Mercury
Mercury is the closest
planet to the Sun

50. Tumors infographics
Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
70% 80% 90% 60%
Earth Saturn
Venus Jupiter
Risk factors
Mercury is the closest planet
to the Sun
+ 60% Probabilities

51. Tumors infographics
Benefits of modern treatments
01 Surgery
Mercury is the closest planet to the Sun and the
smallest one in the entire Solar System
02 Immunotherapy
Mars is a cold place full of iron oxide dust, which
gives the planet its reddish cast
03 Chemotherapy
Saturn is a gas giant and has several rings. It's
composed mostly of hydrogen and helium
04 Radiation therapy
Venus has a very beautiful name but is actually
terribly hot, hotter than Mercury

52. Tumors infographics
Mars
Despite being red,
Mars is a cold place
01
Jupiter
Jupiter is a gas giant
and the biggest planet
02
Neptune
It’s the farthest planet
from the Sun
03

53. Tumors infographics
Lungs
Mercury is the closest
planet to the Sun and
the smallest one in the
entire Solar System
50%
01
Brain
Venus has a very
beautiful name but is
actually terribly hot,
hotter than Mercury
25%
01
Skin
Jupiter is a huge gas
giant named after the
Roman god of the skies
and lightning
60%
01

54. In order to use this template, you must credit Slidesgo in your final presentation.
You are allowed to:
- Modify this template.
- Use it for both personal and commercial projects.
You are not allowed to:
- Sublicense, sell or rent any of Slidesgo Content (or a modified version of Slidesgo Content).
- Distribute Slidesgo Content unless it has been expressly authorized by Slidesgo.
- Include Slidesgo Content in an online or offline database or file.
- Offer Slidesgo templates (or modified versions of Slidesgo templates) for download.
- Acquire the copyright of Slidesgo Content.
Instructions for use
For more information about editing slides, please read our FAQs or visit Slidesgo School:
https://slidesgo.com/faqs and https://slidesgo.com/slidesgo-school

55. Instructions for use (premium users)
As a Premium user, you can use this template without attributing Slidesgo.
You are allowed to:
● Modify this template.
● Use it for both personal and commercial purposes.
● Hide or delete the “Thanks” slide and the mention to Slidesgo in the credits.
● Share this template in an editable format with people who are not part of your team.
You are not allowed to:
● Sublicense, sell or rent this Slidesgo Template (or a modified version of this Slidesgo Template).
● Distribute this Slidesgo Template (or a modified version of this Slidesgo Template) or include it in a database or in
any other product or service that offers downloadable images, icons or presentations that may be subject to
distribution or resale.
● Use any of the elements that are part of this Slidesgo Template in an isolated and separated way from this
Template.
● Register any of the elements that are part of this template as a trademark or logo, or register it as a work in an
intellectual property registry or similar.
For more information about editing slides, please read our FAQs or visit Slidesgo School:
https://slidesgo.com/faqs and https://slidesgo.com/slidesgo-school

56. Infographics
You can add and edit some infographics to your presentation to present your data in a visual way.
● Choose your favourite infographic and insert it in your presentation using Ctrl C
+ Ctrl V or Cmd C + Cmd V in Mac.
● Select one of the parts and ungroup it by right-clicking and choosing
“Ungroup”.
● Change the color by clicking on the paint bucket.
● Then resize the element by clicking and dragging one of the square-shaped
points of its bounding box (the cursor should look like a double-headed arrow).
Remember to hold Shift while dragging to keep the proportions.
● Group the elements again by selecting them, right-clicking and choosing
“Group”.
● Repeat the steps above with the other parts and when you’re done editing, copy
the end result and paste it into your presentation.
● Remember to choose the “Keep source formatting” option so that it keeps the
design. For more info, please visit Slidesgo School.