Industrial biotechnology uses microorganisms and biological processes to produce useful products and materials in a more sustainable way compared to traditional chemical processes. It involves using fermentation and other biological methods to generate chemicals, fuels, foods, and other products from renewable resources. Industrial biotechnology is more efficient and environmentally friendly than petrochemical processes as it uses renewable resources and produces less waste. Some key applications include producing antibiotics, enzymes, organic acids, biofuels, and treating waste and pollution.

1. INDUSTRIAL BIOTECHNOLOGY
SUBMITTED BY SUBMITTED TO
Suman Bhattarai Himal Luitel
Roll No: 50 (Fifty) PhD,AssistantProfessor
B.V.Sc& A.H CenterOf Biotechnology
Agriculture andForestry Agriculture andForestry
University University

2. INDUSTRIAL BIOTECHNOLGY
Depending on the tools and applications, biotechnolgy often overlaps with the fields of
molecular biology, bio-engineering, biomedical engineering, biomanufacturing, molecular
engineering, etc. Since from many years, humankind has used biotechnology in field of
agriculture, food production, and medicine, and many other sectors. Biotechnology is the
branch of science(biology) where living systems and organisms are used to develop or make
commercial useful products, or "any methods that uses biological systems, living organisms,etc.
to make or modify products or processes for specific use for livelihood ". Among different types
of biotechnology used , Industrial Biotechnology is probably one of the biggest booms to have
occurred in our huge field. During last 20 to 30 years the field that is developed so fast is
genetic engineering. Genetic engineering ues rDNA technology to produce products related to
health and medical but that was in early days . In 1980 it was the first time the industrial
biotechnology was used. It tends to be efficient and commercially useful day by day. Before
industrial biotechnology , chemical industry was used to produced commercial products.
Industrial biotechnology uses renewable sources like wheat , corn, straw , etc for useful
products . Chemical industry uses nonrenewable resources like coal gas and petrol derived
from fossils energy.
Industrial biotechnology (known as white biotechnology - in Europe) is the set
of practices used for industrial purposes, including industrial fermentation. It includes use of
cell methods such as microorganisms, or components of cells like enzymes, to generate
industrially useful products such as chemicals, plastics, agricultural and pharmaceutical
products, energy carriers , food and feed, detergents, paper and pulp, textiles and biofuels.
Significant progress has been achieved in creating genetically modified organisms (GMOs) that
enhance the diversity of applications in many sectors and economical viability of industrial
biotechnology. Industrial biotechnology is actively advancing towards lowering greenhouse gas
emissions and moving away from a petrochemical-based economy by using renewable raw
materials to produce a variety of chemicals and fuels,. Use of industrial biotechnology makes
many industries to work more efficient and environmentally friendly, contributing to industrial
sustainability in various ways. This biotechnology changes pharmaceutical and agricultural
techniques that helps us to produce materials such as biopolymers and also bioplastics.
Industrial biotechnology can produce the same results(can exceed) as the petrochemical
industry(that uses fossil energy). Application of biochemistry, microbiology, genomics,
proteomics, bioinformatics, systems biology and process engineering in industrial
biotechnology makes rapid, specialized and competitive growth of the techniques that enable
high productivity, performance and stability. Industrial biotechnology has main role in four
major industrial areas that includes health care (medical), crop production and agriculture,
non-food (industrial) uses of crops and other products (e.g. biodegradable plastics, vegetable
oil, biofuels), and environmental uses. For example, applications of biotechnology by using of
microorganisms for the manufacture of organic products (examples include beer and milk
products). Another example is using naturally present bacteria in the field of mining industry
for bioleaching. Biotechnology is the main tool that is used today to produce biological

3. weapons and to recycle, treatment of waste(effluent treatment), clean up sites contaminated
by industrial activities (bioremediation).
Industrial biotechnology comprises of
 Medium preparations
 Inoculum preparation using industrial strain
 Fermentation process ( science of fermentation is known as zymology )
 Physico chemical separation processes for products purifications
 Packaging
 Effluent treatment ( organic waste treatment )
Industrial biotechnology is also known as white
biotechnology because it have got positive environmental aspects like reduces waste
generation , reduces energy consumption , remove use of solvents , elimination of dangerous
intermediate. The process of biotechnology works by transforming biomass (e.g. organic waste
, algae, agricultural(by) products into biofuels and bio based chemicals. In this way, industrial
biotechnology could save energy in the production processes and could lead to significant
reductions in the green house gas emissions , helping to fight global warming. It can also lead to
improved performance and sustainability for industry and higher value products.Main benefits
are low input of substrate,high rate of output,friendly to environment,renewable,increased
efficiency,etc. While this technology can improve the resilience of crops, they are more
expensive for farmers. The “biotech” seed will be resistant to weed killer and will overgrow and
can ruin the normal seed overgrowing beside them. Similarly, the diseases can become
resistant and unresponsive to antibiotics as they are overprescribed and misused. Plants
affected by biotechnology or engineering may have specific allergens than can affect food
sensitive people.
Its applications are production of biocontrol
agents, fermentation of food products, biobased fuel and energy, recovery of metal ,metabolite
production, etc.
Fig : Antibiotics and
Vitamins

4.  Microorganisms produce a number of metabolites . Eg Antibiotics, enzymes, organic
acids ,vitamins etc.
 Microorganisms enhance the nutrient available to the crops by fixing atmospheric
Nitrogen and solubilizing the soil phosphorous.e.g Rhizobium spp , azotobacter ,BGA etc.
 Fig : Fermentation of food
products
 For recovery of metals, microbes can be employed to recover valuable metals from low
grades ores. E.g leaching of copper as copper sulphates from ores.
 Use of Microorganisms to control insect pests, pathogens,or weeds constitutes biological
control and the biological agents employed for this purpose are called bicontrol agents.
E.g bioinsecticides.

5.  Bio based fuel and energy : ethanol is obtained from fermentation of grain, cellulose
enzyme technology allows conversion of crop residues to ethanol.
# Advantages of industrial biotechnology over chemical industry
1)high reaction rate
2)improved conversional efficiency
3)high product purity
4)lower consumption of energy
5) decrease in chemical waste
Thus, it is the set of practices of using the collection
of various useful scientific techniques and technologies for improvement of both the efficacy
and environmental footprint of the modern industrial production. Microbial technology
constitutes the core of industrial biotechnology(More similarity) . So, microbial technology refer
to the use of microbes to obtain a product or service of economic value( Fermentation).
Industrial biotechnology uses biological resources for industrial processes. White biotechnology
tends to consume less in resources than traditional processes used to produce industrial goods.
In many developing countries like Nepal , industrial biotechnology is growing day by day.
REFERENCES :
 Google Search
 Vet-wikipedia
 Youtube Video
 Senior Notes