To play Powerball, players select 5 numbers between 1 and 59 for the white balls, and one number between 1 and 35 for the red Powerball. The odds of matching all 6 numbers are 1 in 175 million. Purchasing the magayo Lotto software can potentially reduce odds to 1 in 110 million by strategically selecting numbers, as it has helped some users win lottery prizes.