Heartgard Plus and Sentinel are two popular heartworm preventatives for dogs. Both are flavored chewables given once a month that kill parasites like heartworms, roundworms and hookworms. However, Sentinel is also effective against fleas, flea eggs, and whipworms. While Sentinel can be used for dogs as young as 8 weeks, Heartgard Plus is recommended for dogs 6 weeks and older. Sentinel tends to be more expensive but provides additional protection against fleas and whipworms. For collie breeds, Heartgard Plus may cause fewer adverse reactions due to differences in active ingredients between the two medications.

2. Heartgard Plus V/S Sentinel
Comparing two most popular dog
heartwormers
Courtsey:
http://www.buyfleatickmedicine.com/sentinel-versus-heartgard-plus/

3. Heartwormers
The fact that these parasites damage the pet’s heart and lungs leaving
them debilitated calls for a warning. Pet parents need preventives to
avoid heartworm diseases. Adult form of heartworms may cause
fatalities resulting in death of the pet.
Two of the most popular heartworm preventives are Heartgard Plus
and Sentinel.
Here we compare and contrast the specifications and evaluate the
pros and cons of both these treatments.

4. Heartgard Plus & Sentinel: Similarities
•Both are flavored chewables. Pets love the tasty treat and enjoy the
treatment with absolute delight.
•Both are from standard animal pharmaceuticals, they offer good
quality ingredients and high manufacturing standards.
•Both the treatments destroy multiple parasites. Sentinel also kills
flea eggs, roundworms, hookworms, whipworms and immature
heartworms while Heartgard Plus eliminates roundworms,
hookworms and heartworm larvae.
•Both are once a month treatments given as a single dose. When
given on a yearly basis, both will work as preventives and control
internal parasites without any troubles.

5. Heartgard Plus & Sentinel: Dissimilarities
•While Sentinel prevents development of flea eggs, Heartgard plus has
no effect on dog fleas.
•Sentinel are comparatively smaller chews. On the other hand
Heartgard Plus are large chewable tablets.
•Sentinel contains Milbemycin Oxime and Lufenuron as the active
ingredients while the basic constituents of Heartgard Plus are
Ivermectin and Pyrantel pamorate.

6. Heartgard Plus & Sentinel: Dissimilarities
•If you have a Border Collie at home then choosing Heartgard Plus will
give better results because Ivermectin shows adverse reactions in
collie breeds of dogs.
•Sentinel is for 8 weeks or older pups while Heartgard is for 6 weeks
and older pups.
• Sentinel is costlier compared to Heartgard Plus. Although it also gives
additional protection by killing whipworms and flea eggs.

7. Read detailed article:
http://www.buyfleatickmedicine.com/sentinel-versus-heartgard-plus/