This document discusses custom cosmeceutical formulations based on medical image analysis and biometric markers. It describes how skin diagnostics, imaging, and active ingredients have advanced, creating demand for personalized cosmeceuticals. Imaging can quantify markers like wrinkles, pigmentation, pores, and product effects. Biometric measurements of hydration, pH, elasticity and other factors inform targeted formulations. A case study shows formulations improved a woman's spots, dark circles, dryness and laxity based on her images and biometrics before and after treatment. Mass customization using diagnostics can yield optimal skincare results.