Coronary heart disease (CHD) affects over 7 million Americans and is the leading cause of death in the US, killing over 500,000 people each year. It is caused by a narrowing of the coronary arteries due to atherosclerosis. Major risk factors include high blood pressure, high cholesterol, smoking, obesity, diabetes, and stress. Smoking significantly increases the risk of CHD by damaging blood vessels and lowering HDL cholesterol levels. Maintaining a healthy lifestyle through diet, exercise, weight control, and avoiding smoking can help prevent and manage CHD.