This document discusses going hybrid with an on-premises Exchange deployment and Office 365. It outlines the requirements for setting up a hybrid configuration such as having Exchange 2010 SP3 or higher, Office 365 plans that support hybrid, and configuring DNS records. It describes benefits like being able to move mailboxes between on-premises and cloud, centralized transport through Exchange Online Protection, and using the Mailbox Replication Service to migrate mailboxes. Centralized transport and the optional use of Edge servers are also covered at a high level.