This document provides the price list for isotope analysis services from the G.G. Hatch Stable Isotope Laboratory at the University of Ottawa. It lists pricing for the analysis of organic solids, liquids, and gases, as well as inorganic solids and waters. Pricing is provided for common isotopes like carbon, hydrogen, oxygen, nitrogen and sulfur in various forms. The price list also provides rates for use of preparation equipment and notes policies around turnaround times, rush rates, quality control, and customs procedures.
Workflows supporting drug discovery against malariaBarry Hardy
The goal of Scientists Against Malaria (SAM) is the discovery of novel anti-malarial compounds. SAM supports virtual drug discovery organizational structures collaborating on target selection and modeling, protein expression and assay development, computational drug design, and screening. A combination of interoperable information systems, ontologies and web services were designed and deployed to manage the data, documents, computational and assay results, activity and toxicology predictions, as well as dashboards to track project progress and to support decision making. Workflows were developed for consensus virtual screening of candidate malarial kinase inhibitors including docking, pharmacophore-based screening and free energy-based molecular simulations. The models were applied to the discovery of active ligands against a novel target with previously unknown structure or ligands. The workflows were extended to include OpenTox model web services to prioritize drug candidates according to their predicted toxicities, supporting a weight of evidence categorization of candidate molecules according to their activity and toxicity profiles.
This poster is an overview of the four main projects I worked on at my summer at Streck. This board was created as a summary for a all-employee showcase.
Dear Sir / Madam,
Greetings!
Stabicon with three and half years in niche Service provider segment, handling customer ranging from a sole proprietorship pharmaceutical consultancy to multinational pharmaceutical organization with several hundred employees, some of whom go out to perform anything from products manufacturing provider to complete product brand leaders. In course of business we have understood that laboratory activity costing evaluation is a major hurdle and create confusion at management level to take strategic partnering decision of routine Stability, Analytical, Formulation Development activity and etc. There is need for standardized costing model to evaluate in-house GLP regulatory Lab versus strategic partner GLP regulatory lab for activity costing. Please find the enclosed copy of HPLC-UV analysis costing model for Assay/Purity; Related Substances/Impurity/Degradation, Dissolution activity. This presentation will help in taking decision of partnering with specialized lab to support the long-term goals of your business.
We have other costing model available for Formulation Development, Microbiology Analysis ,Analytical Validation, Stability Storage and Complete product Analysis. Apart from these costing models, we also offer service based on Full Time Equivalent, Complete facility setting up and Operation Model.
Let us know if you would be interested in partnering with us with return email specifying area of interest to discuss further.
Attachment Link: HPLC COSTING
Thanks & Regards,
S. Sujin,
Team – Business Development
Email: Sujin@stabicon.com
Stabicon Life Sciences Pvt. Ltd.
Plot No. 28 l Bommasandra Industrial Area l 4th Phase l Jigani hobli l Anekal Taluk l Bangalore - 560 100 l India l
R&D Centre: +91 80 27839259/ 9260 l Corporate Office: +91 80 41285405 l Website: www.stabicon.com l
Accreditations: WHO | NABL | CDSCO | HEALTH CANADA |
About Us: Presentation | Outsourcing | Video | Route Map |
Think Green!!! Before printing this e-mail |
Workflows supporting drug discovery against malariaBarry Hardy
The goal of Scientists Against Malaria (SAM) is the discovery of novel anti-malarial compounds. SAM supports virtual drug discovery organizational structures collaborating on target selection and modeling, protein expression and assay development, computational drug design, and screening. A combination of interoperable information systems, ontologies and web services were designed and deployed to manage the data, documents, computational and assay results, activity and toxicology predictions, as well as dashboards to track project progress and to support decision making. Workflows were developed for consensus virtual screening of candidate malarial kinase inhibitors including docking, pharmacophore-based screening and free energy-based molecular simulations. The models were applied to the discovery of active ligands against a novel target with previously unknown structure or ligands. The workflows were extended to include OpenTox model web services to prioritize drug candidates according to their predicted toxicities, supporting a weight of evidence categorization of candidate molecules according to their activity and toxicity profiles.
This poster is an overview of the four main projects I worked on at my summer at Streck. This board was created as a summary for a all-employee showcase.
Dear Sir / Madam,
Greetings!
Stabicon with three and half years in niche Service provider segment, handling customer ranging from a sole proprietorship pharmaceutical consultancy to multinational pharmaceutical organization with several hundred employees, some of whom go out to perform anything from products manufacturing provider to complete product brand leaders. In course of business we have understood that laboratory activity costing evaluation is a major hurdle and create confusion at management level to take strategic partnering decision of routine Stability, Analytical, Formulation Development activity and etc. There is need for standardized costing model to evaluate in-house GLP regulatory Lab versus strategic partner GLP regulatory lab for activity costing. Please find the enclosed copy of HPLC-UV analysis costing model for Assay/Purity; Related Substances/Impurity/Degradation, Dissolution activity. This presentation will help in taking decision of partnering with specialized lab to support the long-term goals of your business.
We have other costing model available for Formulation Development, Microbiology Analysis ,Analytical Validation, Stability Storage and Complete product Analysis. Apart from these costing models, we also offer service based on Full Time Equivalent, Complete facility setting up and Operation Model.
Let us know if you would be interested in partnering with us with return email specifying area of interest to discuss further.
Attachment Link: HPLC COSTING
Thanks & Regards,
S. Sujin,
Team – Business Development
Email: Sujin@stabicon.com
Stabicon Life Sciences Pvt. Ltd.
Plot No. 28 l Bommasandra Industrial Area l 4th Phase l Jigani hobli l Anekal Taluk l Bangalore - 560 100 l India l
R&D Centre: +91 80 27839259/ 9260 l Corporate Office: +91 80 41285405 l Website: www.stabicon.com l
Accreditations: WHO | NABL | CDSCO | HEALTH CANADA |
About Us: Presentation | Outsourcing | Video | Route Map |
Think Green!!! Before printing this e-mail |
Accurex Biomedical Pvt. Ltd. is an Indian manufacturer and marketer which provides accurate and quality solutions in the diagnostic industry. We have been in this business for over 38 years and are currently one of the top 3 Indian companies in the field of Clinical chemistry, known for high quality of products.
Our company name is composed of two words, ACCU and REX. ‘ACCU’ refers to the word ‘accurate’. Its definition as described by Oxford dictionary portrays the essence of our existence. ‘REX’, a Latin word for ‘king’, speaks of our authoritative influence in the diagnostic industry.
Guided by clear vision and driven by innovation; Accurex has gained considerable expertise in manufacturing and marketing of In-vitro Diagnostic reagents. It has built a reputation of quality products, a strong financial base and dynamic marketing.
Accurex is a leader in the In-vitro Diagnostic segment in India, with world-class products and solutions in all segments - Clinical Chemistry, Critical Care, Diabetes Management, Haematology, Immunology, Microbiology, Molecular and Urinalysis.
Over 3 decades, Accurex believes in providing Accuracy, best quality and affordable prices. We believe that quality healthcare should be available for all. Accurex is striving for the best in products and service.
Why Isn't My Query Using an Index?: An Introduction to SQL Performance TechExeter
by Chris Saxon, Oracle.
“Why isn’t my query using an index?” is a common question people have when tuning SQL.
This talk explores the factors that influence the optimizer’s decision behind this question. It introduces the concepts of blocks and the clustering factor. It discusses how these affect the optimizer's calculations. It goes on to show how these concepts work in practice using real SQL queries.
This session is intended for developers who want to learn how the optimizer works and how to make their SQL run quickly!
From the FreshTech 2017 conference by TechExeter
www.techexeter.uk
Similar to G.G. Hatch Lab. Price List (Ottawa Univ.) (13)
Why Isn't My Query Using an Index?: An Introduction to SQL Performance
G.G. Hatch Lab. Price List (Ottawa Univ.)
1. 8/29/2015 G.G. Hatch Stable Isotope Laboratory- Price list
http://www.isotope.uottawa.ca/prix-prices/price-list-new.html 1/4
Faculty of Science G.G. Hatch Stable Isotope Laboratory
G.G. Hatch Stable Isotope Lab Price List
University of Ottawa and OCGC researchers please contact us for internal prices.
Prices are in Canadian Dollars, and do not include GST.
Price list is in effect from March 1, 2015.
Organic Solids
NSERC /
CanGov
Private /
Other
Amount
(1 analysis)
%nchs Microcube EA $13 $18 1-10 mg
13C & 15N, or 15N only
Isotopecube -
IRMS
$15 $20 100 ug N
13C only
Isotopecube -
IRMS
$15 $20 400 ug C
2H Pyrocube + IRMS $20 $25 0.2-5 mg
2H + equilibration Pyrocube + IRMS $60 $70 2 x 0.2 mg
18O Pyrocube + IRMS $20 $25 0.2-5 mg
34S Microcube +IRMS $18 $23 50 ug S
Organic Liquids
NSERC /
CanGov
Private /
Other
Amount
(1 analysis)
%nchs Microcube EA $13 $18 1-10 mg
13C & 15N, or 15N only
Isotopecube -
IRMS
$15 $20 100 ug N
13C only
Isotopecube -
IRMS
$15 $20 400 ug C
13C GCIsolink - IRMS
Contact
Us
Contact
Us
Contact Us
Inorganic Solids
NSERC /
CanGov
Private /
Other
Amount
(1 analysis)
%nchs Microcube EA $13 $18 1-10 mg
2H Pyrocube +IRMS $20 $25 0.2 ug H
13C &/or 18O
(carbonate)
Gasbench - IRMS $20 $25
0.5-0.7 mg
(pure)
2. 8/29/2015 G.G. Hatch Stable Isotope Laboratory- Price list
http://www.isotope.uottawa.ca/prix-prices/price-list-new.html 2/4
carbonate offline extract for 14C $50 $60 2-4 mg C
18O (sulphate) Pyrocube +IRMS $30 $35 0.2 mg
34S (sulphide/sulphate) Microcube +IRMS $18 $23 50 ug S
Waters
NSERC /
CanGov
Private /
Other
Amount
(1 analysis)
2H & 18O+17O
LGR
(Includes filtering +
pipet into vials)
$25 $30 1.0 mL
2H Gasbench - IRMS $20 $25 0.2-0.6 mL
18O Gasbench - IRMS $20 $25 0.2-0.6 mL
2H & 18O Gasbench - IRMS $35 $45 0.2-0.6 mL
17O & 18O (dissolved) Gasbench - IRMS $22 $27 12 mL
ppmC Aurora $15 $20 40 mL
13C dic/tic (fresh) Aurora(wet)- IRMS $25 $30 2x40 mL
13C doc/toc (fresh) Aurora(wet)- IRMS $25 $30 2x40 mL
13C doc/toc (SALINE;
35psu max)
Sparge - Aurora
(combustion) -
IRMS
$35 $40 40 mL
13C doc/toc (SALINE +
enriched)
Sparge - Aurora
(combustion) -
IRMS
$45 $50 40 mL
EPA vial Dilution Off-line $10 $15
Transfer to EPA vial Off-line $5 $5
Sparging only Off-line $15 $20
dic offline extraction for 14C $85 $110 2-4mg C
doc offline extraction for 14C $95 $120 2-4mg C
filtering Off-line $30 $40
3. 8/29/2015 G.G. Hatch Stable Isotope Laboratory- Price list
http://www.isotope.uottawa.ca/prix-prices/price-list-new.html 3/4
Gases
NSERC /
CanGov
Private /
Other
Amount
(1 analysis)
13C (break seals) Dual Inlet - IRMS $15 $20 50-100 uM
2H (methane, etc.) GCIsolink- IRMS
Contact
Us
Contact
Us
Contact Us
13C (CO2, methane,
etc.)
GCIsolink - IRMS
Contact
Us
Contact
Us
Contact Us
15N GCIsolink- IRMS
Contact
Us
Contact
Us
Contact Us
concentrations only SRI GC $35 $45 Contact Us
concentrations
(dissolved)
SRI GC $45 $55 Contact Us
dilution Off-line $20 $20
Use of Prep Equipment
NSERC /
CanGov
Private /
Other
Microbalance (no submission) $25/hr $30/hr
Micromill (high precision drill) $25/hr $30/hr
Ball Mill (organic material grinder) $7/sample $10/sample
Grinding by mortar and pestle $15 $20
Acidification of sediments/soils $25 $30
Prices are subject to change.
Additional Notes:
Please click on each table heading above for more detailed information.
Left-over sample material will be retained for 6 months after completion.
Turn around time is usually better than 3 months. Large batches may take longer.
Priority is given to internal projects when possible; however, this is not a "rush" equivalent.
Priority is also given to all 4th year thesis projects due to the limited time constraints.
Discount of $5 per sample applies if researcher/student does the prep (except for Aurora).
"Rush" rate: 1-29 samples = triple the regular rate.
"Rush" rate: 30+ samples = double the regular rate.
The Lab reserves the right to adjust the "rush" rates as needed.
10% quality control duplicates (QCD) are included at no charge.
Additional duplicates/replicates are recommended for homogeneity and statistical
information.