Galaxies change over time through interactions and mergers with other galaxies. Studies in the late 1970s and early 1980s by Butcher and Oemler found that galaxy clusters at intermediate distances contained more blue, star-forming galaxies than nearby clusters, indicating that galaxies in denser environments were more likely to have their gas stripped through interactions, quenching star formation. This phenomenon is known as the Butcher-Oemler effect and provided early evidence that galaxy properties depend on their surrounding large-scale environment.