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SKLBC-CHINA
1
WEiGEM
2.0
LAB
WORK
1 KG
Bio-BOX
2
NEW BASIC PART
miRNA-397
3
LAB WORK NEW PART
In Rice→
Downregulate the Target(OsLAC)→
Increase the Yield
LAB WORKLAB WORK
NEW BASIC PART
miRNA-397
4
In Rice Genome
→No Target In Human
→Safe Expression
NEW PARTLAB WORK
VIEW PLASMID
5
EXPERIMENTNEW PARTLAB WORK
CHARACTORIZATION OF PART
Bba_K1218011
6
NEW PARTLAB WORK Cas9 PART
7
SKILLS
WE GAIN SKILLS
1.PCR TECNOLOGY
2. EXPERIMENT SAFTY
3. EQUIPMENT
LAB WORK NEW PART Cas9 PART
8
9
WEiGEM 1.0
2014 Best Software Tool
10
30000+ Bricks
In Your Pocket
WHY
WECHA
T?
11
600,000,000 USERS
12
1/10OF WORLD’S
POPULATION
13
14
Advanced Searching
Prefix & Suffix Addition
Convenient Mark-and-Share
Online Community
NEW FEATURES
ADVANCED
SEARCHING
15
16
18
CONVENIENT
19
MARK & SHARE
Collect Your
BioBricks
20
Collect Your
BioBricks
21
Mark Your
BioBricks
22
Mark Your
BioBricks
23
PREFIX & SUFFIX
ADDITION
24
Add Prefix
&Suffix
25
Add Prefix
&Suffix
26
27
Copy
Sequence
28
Copy
Sequence
29
ONLINE&OFFLINE
COMMUNITY
Academic Articles
Fun Facts
about
Synthetic
Biology
Latest Researches
30
Share&Discuss
Articles
31
Offline
Discussion
32
Online
Seminars
33
34
Offline Seminars
ADVANCED
SEARCHING
CONVENIENT
M
ARK
&
SHARE
ONLINE&OFFLINE
COM
M
UNITY
PREFIX
&
SUFFIX
ADDITION
35
EDUCATION AND
PUBLIC
ENGAGEMENT
36
37
1 KG BIO-BOX
ABSTRACT
TEXTBOOK
SYNTHETIC BIOLOGY
CONCEPTS
?
38
1 KG BIO-BOX
53.8%
39
1 KG BIO-BOX
1 KG BIO-BOX
40
ELECTRIC
CIRCUIT
BIO-BRICK
CIRCUIT
LEGO
41
1 2
3 4
42
5 6
7 8
DEMO
43
1 KG BIO-BOX
44
1 KG BIO-BOX
HANDS-ON
EXPERIENCE
SCAN
WEiGEM
COMMUNITY
ONLINE
COURSES
ONLINE
ARTICLES
OFFICIAL
ACCOUNT
45
LINK TO
IGEM.org
46
1 KG BIO-BOX
“ We could learn more on the…”
“ I can see how bio-bricks connected to
make a protein.”
“ It was the most interesting bio
lecture I have ever experienced!”
47
1 KG BIO-BOX
“ The game was great, and I really
wonder how the bio-bricks
influence the change of the
functions of the E.coli…”
—a student from Guangzhou No.3
High School
48
1 KG BIO-BOX
“ …I thought the clues were a
little bit easy for my students, I
want it to be more
challenging…”
—a teacher from Zhixin Middle school
AIJU
— a social enterprise
MEET UP 3 PROBLEMS LEGO AIJU
49
1 KG BIO-BOX
546SCHOOLS
50
1 KG BIO-BOX
55,600STUDENTS
51
1 KG BIO-BOX
52
1 KG BIO-BOX
REUSABLE AND
AVAILIBLE FOR
ANYONE
53
Guangdong Xiangxian
Middle School
54
1 KG BIO-BOX
Guangya
Middle School
55
1 KG BIO-BOX
A Survey
After 1 KG BIO-BOX
DID YOU
HAVE FUN?
DID YOU GET
TO KNOW
SYNTHETIC
BIOLOGY?
ARE YOU
INTERESTED IN
FURTHER
STUDY OF
IGEM?
1 2 3
56
90.6%
YES
83.7%
YES
70.3%
YES!!
1 KG BIO-BOX
57
1 KG BIO-BOX
In China
In America
In the world
SPONSORS
THE AFFILIATED
HIGH SCHOOL OF
SOUTH CHINA
NORMAL
GUANGZHOU
XIANGXIAN
HIGH SCHOOL
SCHOOL OF
LIFE SCIENCE
SUN YAT-SEN
UNIVERSITY
STATE KEY
LABORATORY
OF
BIOCONTROL
(SUN YAT-SEN
UNIVERSITY)
SCHOOL OF
INFORMATION
TECHNOLOGY
AND
COMPUTER
SCIENCE
58
SPONSORS
GUANGDONG
EXPERIMENTAL
MIDDLE
SCHOOL
GUANGZHOU
NO.6 ,MIDDLE
SCHOOL
GUANGDONG
GUANGYA
MIDDLE
SCHOOL
ZHIXIN
HIGH SCHOOL
GUANGZHOU
NO.3 HIGH
SCHOOL
59
THANKS FOR LISTENNING!
60
Q & A

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FINAL 泡泡堂

Editor's Notes

  1. 这个勾颜色恶心了点
  2. 这里讲我们学到什么,我们找到了很多与大学学习的机会,而且学习到了很多的实验技巧。不过我们也想到了许多我们在实验中遇到的问题…
  3. 也很突兀,试着和过渡结合,毕竟这里听不出过渡(
  4. 也很突兀,试着和过渡结合,毕竟这里听不出过渡(
  5. Reusable Innovative 是否建立起我们与公众之间的交流 学到了什么
  6. 1. it is pretty obvious that the concept of the bio brick circuit is a hard part in biology lessons. The undergraduate or high students have difficulties in comprehending the abstract concepts.
  7. 1. We handed out questionnaires to 923 students,who have been taught concepts of synthetic biology in nineteen middle schools in china. And we have found that, 497 of them, about 53.8% didn't really get the idea of what is bio-bricks and how they works.
  8. 1. So in order to solve these difficulties, we made an innovative and tangible teaching kit with bio-brick models called the 1 kg bio-box.
  9. 1. We used the idea of lego and electric circuit when making the bio-brick model. Think about it, you can actually imagine bio-bricks as lego like building blocks that are connected to each other to approach different functions like elements in an electric circuit . * so what we have done is we made bio-bricks into actual touchable models similar to lego, and innovatively combined the ABSTRACT bio brick circuit with electric circuit that high school students are really familiar with.
  10. 1. So here is how the game goes. Suppose I am a kid from grade 10 that attended the one kilo bio-box synthetic biology game.The game is set in the background that a polluted river needs us to reconstruct a plasmid in a e.coli and create a testing kit to find out the cause of the pollution. So the game's final mission is to find out the correct order of the bio-bricks and put it into the ecoli model. But what is bio-bricks and what is the correct order?
  11. 1. To answer these questions, we went over some missions provided in the box and got synthetic biology clues for the final mission. By analyzing the clues and working with the biobrick models in the final mission, i have totally got the idea of what is biobricks and how it works.
  12. 1. So now i will give you guys a live demo of our box. In the final mission, you have to put the bio-bricks models into correct order according to the clues, like this, and once you did that, the proteins here on the e.coli board will light up. (change the order.) and if the order is incorrect, like if i swap the terminator and promoter, the lights won't go up.
  13. 1. As you can see, this box allows teenagers to actually get their hands onto the bio-bricks and physically experience the idea of how the bio bricks connect each other in specific sequence and how they function.
  14. 1. So now let's take a look at the programs we provide after the game. the teenagers scan the QR code printed on the ecoli board model and enter our WEiGEM2.0 official account, there are online courses and articles for further knowledge of synthetic biology and also guidance to IGEM.
  15. 1. Like this one asked how does the ecoli approach different functions, so we added three sets of biobricks for the coding area. When you put different biobricks into the plasmid, different color lights will light up representing different functions.
  16. Moreover, there are questionnaires where users interacted with our team and give us feedbacks..according to these feedbacks, we have constantly improved our project. Here are some feed backs we have got.
  17. 1. and this one informed that the clues in the box is actually a little bit to easy for her, so we made different versions of the 1 kg bio-box for different age groups,--kids, junior, senior,and undergraduates..
  18. 1. This summer, we found Aiju, a social enterprise, we cooperated with them and with the help of Aiju, the influence range of our box widened
  19. to 556 schools,
  20. to 55,600 students.
  21. 1. That means, 10% of the Chinese high schools and its student can get to know synthetic biology and everyone of them will have the chance to become one of us here, isn't it incredible?
  22. 1. So you may ask How does our box spread? Well, our box is reusable and available for any one,any school, for other teams, for engager or for educators. All you have to do is apply on our official account or through aiju and bring the box back in classroom.! What's more, our box can be used as many times as you want, that means, the influence of one particular box can significantly keep building up in the whole school.
  23. Lately, we have been trying out our box in schools in china. Here are some picture taken from the games.
  24. 这里我尽快拿到照片,最好框一框,不然色调冲了很难看
  25. 1. We did a survey after each of the game, we asked 216 students three question,* first, did you have fun? 90.6%(196) said yes.* Second, did you get the idea of synthetic biology? 83.7%(181) said yes. * And the most exciting thing was when we asked them, are you willing to learn more about synthetic biology? 70.3%(152) said yes.
  26. 1. So today we are presenting you the 1 kg bio-box, the tangible teaching tool that lets students feel synthetic biology with their hands. We hope that one day, this great teaching tool can brighten every bio lecture in china,and hopefully in america, and in the world.