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The document discusses joint replacement surgery, focusing on which joints are most commonly replaced and when a patient should consider having the surgery. It notes that hip and knee replacements are most common, performed on over 100,000 people annually in the UK. It then explores the views and behaviors of various parties involved in the joint replacement process, including patients, general practitioners, and orthopedic surgeons. Based on research involving patients, it concludes that pain and disability level should be the main criteria for considering surgery, rather than a doctor's focus on age, weight or x-ray findings alone. It recommends developing local appropriateness criteria involving patients, doctors and other staff to help make decisions more consistent and fair.
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La empresa se dedica a la comercialización de tara en polvo a industrias. Depende de proveedores locales en Huánuco para pulverizar la tara. Usa un bróker en Italia para distribuir el producto a empresas industriales en ese país, aprovechando la relación familiar con el bróker. Busca fidelizar clientes a través de comunicación directa y saludos en fechas especiales para generar confianza. Su fuente principal de ingresos es la venta de tara en polvo a brókeres para su distribución.
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Genetic, epigenetic, and computational screening approaches were used to identify 43 genes located in the 6q12-27 region for characterization of methylation status in lung cancer. Twelve genes showed methylation in lung cancer cell lines, with five genes (TCF21, SYNE1, AKAP12, IL20RA, and ACAT2) exhibiting the highest prevalence of methylation. These five genes showed similar methylation patterns in lung adenocarcinoma tumors regardless of smoking status, but their methylation was not associated with patient survival.
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This document describes four new species of Clavicornaltica, a genus of tiny flea beetles. Two new species, C. dali and C. longsheng, are described from China, while C. tamdao and C. vietnamensis are described from Vietnam. Descriptions of the wing and metathorax of Clavicornaltica are also provided for the first time. A key is presented to differentiate the four new species. Male genitalia are illustrated for one known species.
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