According to the presentation, there are several things to consider when making an effective PowerPoint. These include avoiding only black and white slides as they are simple, using pictures related to the topic, and ensuring the text is at least 24pt or 36pt for headings. It is also important to remember keyboard shortcuts like B or W to move between slides, Ctrl P to change to a pen to annotate, Ctrl H to hide the pointer, and commands to move between specific slides.