Dojo is an open source JavaScript framework for building interactive web applications. It includes utilities for DOM manipulation, Ajax requests, events, animation and more. Dojo has adopted the AMD (Asynchronous Module Definition) standard, allowing code to be organized into modular and reusable components. Popular Dojo components include Dijit for widgets and Dojox for extensions. Common tasks like DOM selection, event handling and Ajax calls can be simplified using Dojo utilities.