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This document summarizes a study on how mRNA abundance increases in brown adipose tissue (BAT) during hibernation arousal cycles in ground squirrels. The study found that:
1. Transcript abundance of BAT activity genes increases during torpor, but steady state levels decrease.
2. This is because most transcripts are degraded during torpor, while select transcripts containing long poly(A) tails are stabilized.
3. Polyadenylation confers stability to these transcripts, allowing abundance to increase through preservation rather than new transcription during arousal from torpor.
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This document summarizes a study on how mRNA abundance increases in brown adipose tissue (BAT) during hibernation arousal cycles in ground squirrels. The study found that:
1. Transcript abundance of BAT activity genes increases during torpor, but steady state levels decrease.
2. This is because most transcripts are degraded during torpor, while select transcripts containing long poly(A) tails are stabilized.
3. Polyadenylation confers stability to these transcripts, allowing abundance to increase through preservation rather than new transcription during arousal from torpor.
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The document discusses drawing with shapes and values. It begins by defining key vocabulary terms like line, shape, value, and form. It then shows a progression from simple lines to combining lines to create shapes, and adding value to create the illusion of three dimensions. Later steps involve identifying values in a photograph by creating a value scale, then drawing objects without using lines by relying only on shapes and implied values/shading. The document emphasizes techniques like drawing without lines, shading without smudging, and "drawing backwards" on black paper with white charcoal. It appears to be teaching materials outlining lessons and exercises for students to practice observational drawing using shape and implied value/shading rather than lines.
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O documento discute o desenvolvimento de sistemas utilizando a Linguagem de Modelagem Unificada (UML). Apresenta as fases do desenvolvimento de um sistema em UML, incluindo análise de requisitos, análise, design, programação e testes. Também descreve os principais diagramas e elementos da UML como classes, objetos, relacionamentos e diagramas de casos de uso, classes, sequência e atividade.
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