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HYPOTHESES
REFERENCES
RESULTS & CONCLUSIONSBACKGROUND
THE RELATIONSHIP BETWEEN HANDEDNESS AND
ACTIVATION IN THE VISUAL CORTEX OF THE BRAIN
SEHGAL, N., VINCI-BOOHER, S., & JAMES, K.H.
DEPARTMENT OF PSYCHOLOGICAL AND BRAIN SCIENCES, INDIANA UNIVERSITY BLOOMINGTON
COGNITION AND ACTION NEUROIMAGING LABORATORY
ANALYSIS
3) Performed Pearson correlations between EHS and
all 4 ROIs & all 4 ROIs with each other
STUDY DESIGN4
Subject AB Subject DS Subject LS
Collapsed across letter conditions and
shape conditions (letter vs. shape)
Functional magnetic resonance
imaging (fMRI) conditions Standardized data (raw and demeaned)
Sample size: n=10
Average age: 56.2
months
St. dev: 3.54 months
1) Analyzed subject characteristics
2) Extracted ROI time course data anatomically located on each
individual
1) LAFG and LPFG are highly correlated with each other
RAFG and RPFG are highly correlated with each other
2) LAFG/LPFG correlated with RAFG/RPFG in raw
correlations
LAFG/LPFG anti-correlated with RAFG/RPFG in
demeaned correlations
1) EHS is more positively correlated with LAFG/LPFG
EHS is more negatively correlated with RAFG/RPFG
1) LAFG has the highest positive correlation with EHS
2) Correlations with EHS were stronger for letters than
shapes in general
• Motor: Right-handers showed increased activation in left
motor areas after handwriting experience; left-handers
showed increased activation in right-hemisphere
homologue1.
• Visual: Right-handers show increased activation from the
left fusiform gyrus after handwriting experience2.
• Asymmetrical weight of right and left hemispheres is
possibly related to handedness3.
LAFG
Left Anterior
Fusiform Gyrus
LPFG
Left Posterior
Fusiform Gyrus
Sensorimotor
Training
Visual Training
RAFG
Right Anterior
Fusiform Gyrus
RPFG
Right Posterior
Fusiform Gyrus
1) Handedness scores will show stronger correlations
with activity in all 4 perceptual areas (LAFG, LPFG,
RAFG, RPFG) for letters than shapes.
1) It is also expected that the Edinburgh Handedness
Scores (EHS) will be positively correlated with the
LAFG/LPFG and negatively correlated with the
RAFG/RPFG.
1Longcamp, M., Zerbato-Poudou, M. T., & Velay, J. L. (2005). The influence of writing practice on
letter recognition in preschool children: A comparison between handwriting and typing. Acta
psychologica, 119(1), 67-79.
2James, K. H. (2010). Sensori‐motor experience leads to changes in visual processing in the
developing brain. Developmental science, 13(2), 279-288.
3Behrmann, M., Plaut, D.C. (2013). Distributed circuits, not circumscribed centers, mediate visual
recognition. Trends in Cognitive Sciences, 1-10.
4James, K. H., & Engelhardt, L. (2012). The effects of handwriting experience on functional brain
development in pre-literate children. Trends in Neuroscience and Education, 1(1), 32-42.
Indicates a role for neural efficiency as a developmental
mechanism and displays the importance of action in the
development of perception.

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Cewit poster

  • 1. HYPOTHESES REFERENCES RESULTS & CONCLUSIONSBACKGROUND THE RELATIONSHIP BETWEEN HANDEDNESS AND ACTIVATION IN THE VISUAL CORTEX OF THE BRAIN SEHGAL, N., VINCI-BOOHER, S., & JAMES, K.H. DEPARTMENT OF PSYCHOLOGICAL AND BRAIN SCIENCES, INDIANA UNIVERSITY BLOOMINGTON COGNITION AND ACTION NEUROIMAGING LABORATORY ANALYSIS 3) Performed Pearson correlations between EHS and all 4 ROIs & all 4 ROIs with each other STUDY DESIGN4 Subject AB Subject DS Subject LS Collapsed across letter conditions and shape conditions (letter vs. shape) Functional magnetic resonance imaging (fMRI) conditions Standardized data (raw and demeaned) Sample size: n=10 Average age: 56.2 months St. dev: 3.54 months 1) Analyzed subject characteristics 2) Extracted ROI time course data anatomically located on each individual 1) LAFG and LPFG are highly correlated with each other RAFG and RPFG are highly correlated with each other 2) LAFG/LPFG correlated with RAFG/RPFG in raw correlations LAFG/LPFG anti-correlated with RAFG/RPFG in demeaned correlations 1) EHS is more positively correlated with LAFG/LPFG EHS is more negatively correlated with RAFG/RPFG 1) LAFG has the highest positive correlation with EHS 2) Correlations with EHS were stronger for letters than shapes in general • Motor: Right-handers showed increased activation in left motor areas after handwriting experience; left-handers showed increased activation in right-hemisphere homologue1. • Visual: Right-handers show increased activation from the left fusiform gyrus after handwriting experience2. • Asymmetrical weight of right and left hemispheres is possibly related to handedness3. LAFG Left Anterior Fusiform Gyrus LPFG Left Posterior Fusiform Gyrus Sensorimotor Training Visual Training RAFG Right Anterior Fusiform Gyrus RPFG Right Posterior Fusiform Gyrus 1) Handedness scores will show stronger correlations with activity in all 4 perceptual areas (LAFG, LPFG, RAFG, RPFG) for letters than shapes. 1) It is also expected that the Edinburgh Handedness Scores (EHS) will be positively correlated with the LAFG/LPFG and negatively correlated with the RAFG/RPFG. 1Longcamp, M., Zerbato-Poudou, M. T., & Velay, J. L. (2005). The influence of writing practice on letter recognition in preschool children: A comparison between handwriting and typing. Acta psychologica, 119(1), 67-79. 2James, K. H. (2010). Sensori‐motor experience leads to changes in visual processing in the developing brain. Developmental science, 13(2), 279-288. 3Behrmann, M., Plaut, D.C. (2013). Distributed circuits, not circumscribed centers, mediate visual recognition. Trends in Cognitive Sciences, 1-10. 4James, K. H., & Engelhardt, L. (2012). The effects of handwriting experience on functional brain development in pre-literate children. Trends in Neuroscience and Education, 1(1), 32-42. Indicates a role for neural efficiency as a developmental mechanism and displays the importance of action in the development of perception.