2. BRAIN TUMOR
Brain tumors are expanding lesions within the skull
20% of childhood malignant tumors are brain tumors
Benign tumors may be life threating if it is located in
the vital areas of the brain
4. CLASSIFICATION
(i)Infratentorial tumors –tumors occurs in the area of the
brain below tentorium cerebelli involving cerebellum or
brainstem
(ii) Supratentorial tumors - tumors occurs in the area of
the brain above tentorium cerebelli
5. CLASSIFICATION
(I) Infratentorial tumors
a) Medulloblastoma
b) Cerebellar Astrocytoma
c) Glioma
d) Ependymoma of the fourth ventricle
(II)Supratentorial tumors
a) Craniopharyngioma
b) Hypothalamic glioma
c) Glioma of optic nerve
d) Primitive neuroectodermal tumor/cerebral neuroblastoma
6. PATHOPHYSIOLOGY
Due to etiology
Space occupying lesion
Tumor cell proliferation, enlarging tumor
Cerebral edema Compress brain tissue
Increased ICP Altered blood flow
Herniation of brain Ischemia Necrosis
Neurological deficits
Signs and symptoms depend on the location of the tumor
7. INFRATENTORIAL TUMORS
Medulloblastoma:
These are midline cerebrallar tumors and occurs in
infancy
Fast growing and malignant
Craniospinal spread along with neuraxis is common and
death occurs early.
8. CONT….
Medulloblastoma:…….
Clinical features
• Truncal ataxia
• Early pappiledema
• Unsteadiness in sitting position
Tendency to walk with a broad base gait
hydrocephalus
Management
Radiation
Chemotherapy
VP shunt
9. CEREBRAL TUMORS…..
Cerebellar Astrocytoma
Common in the cerebellar hemisphere
Clinical feature
Ataxia and incordination are common on the side of lesion
Nystagmus
Areflexia and hypotonia
Head is tilted to the side of the lesion –to relieve the increased
ICP
Management
Chemotherapy
Radiation –brachytherapy
Surgical excision
10. CONT..
BRAIN STEM GLIOMA
• Worst prognosis
• Most child die within 18months
Clinical features
• Gait disturbance
• Headache, nausea, vomiting
• Cranial nerve defecits-diplopia,facial asymmetry
• Papilledema
• Hydrocephalus
• Failure to thrive
12. CONT…
Ependymoma of the fourth ventricle:
Occurs in first decade of life
Flow of CSF is obstructed leads to increased
intracranial pressure
Signs of increased ICP
Management
Surgical excision is rarely possible
Chemotherapy and radiation therapy
VP shunt
13. SUPRATENTORIAL TUMORS
Craniopharyngioma:
It is congenital and arises from squamous epithelial cells of the
embryonic rathke pouch
Clinical features:
• Growth failure
• Bitemporal hemianopsia
• Asymmetric or unilateral visual field defects
• Signs of increased ICP
• Endocrine abnormalities – DI,delayed puberty
Management
• Chemotherapy, Radiation therapy
• Surgical excision is rarely possible
14. SUPRATENTORIAL TUMORS….
Hypothalamic glioma
Clinical features
Failure to thrive
Loss of subcutaneous fat
Sleep disturbance
Respiratory disturbance
Older children may have precocious puberty
MANAGEMENT
Radiation therapy
Chemotherapy
Surgical excision(based on size and metastasis)
15. SUPRATENTORIAL TUMORS….
Glioma of optic nerve
Clinical features
Visual disturbances
Squint
Proptosis
Exophthalmos
Optic atrophy
MANAGEMENT
Chemotherapy and radiation therapy
Surgical excision is possible if the tumor is limited to
one side
16. CONT
Primitive neuroectodermal tumor/cerebral
neuroblastoma
malignant tumor arise from primitive nerve cells
Clinical features
• Headache,seizures,loss of co-ordination
• Vertigo,diplopia,problems with walking and balance
• Weight loss
• Behavioral changes
MANAGEMENT
• Radiation, chemotherapy
• surgery
18. NURSING MANAGEMENT
PRE-OPERATIVE
Monitor vital signs
Perform neurological assessment
Measure head circumference
Monitor symptoms of Cushing triad
Document child’s gait ,behavior, changes in posture etc
Administer pre-operative medications
19. CONT….
POST OPERATIVE
• Vital signs monitoring every 15 to 30mts until the child
is stable
• Hyperthermia may occurs due to surgical intervention in
the hypothalamus/brainstem
• Provide a cooling blanket(if needed) for the child and
monitor body temperature carefully because of risk for
hypothermia.
20. CONT….
Perform neurological assessment including pupillary
reaction,LOC,reflexes.
Monitor surgical dressing for evidence of drainage if it
is present apply sterile dry gauze.
Monitor and record the amount of drainage(drain placed
in the operative site)
Positioning
• Correct positioning after surgery is critical to prevent
pressure against operative site, ICP and aspiration
21. CONT….
Positioning…………
If a large tumor is removed the child is not placed on the
operative side because the brain may suddenly shift to
that cavity leads to damages to blood vessels, linings
and the brain itself
Infratentorial procedure:
• Positioned on either side with the bed flat
• Keep the child NPO for 24 hrs if the gag and
swallowing reflex are depressed or the child is comatose
22. CONT….
Positioning…………
Supratentorial procedure:
• head of bed is elevated 20 to 30 degrees with the child
either side or on the back
• Cranial neuropathy is less likely occurs so clear fluids
can be given soon after the child is alert, sometimes
within 24hrs.
23. CONT….
Provide extra pillows for comfort
Maintain hydration by IV fluid until oral fluids are well
tolerated
Implement interventions for reducing headache
Clam and quite environment
Restrict visitors
Prevent sudden occurrence of jarring movements
Administer analgesics – acetaminophen, codeine
Cold application