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Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering. This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
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Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Call for Papers - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
CALL FOR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
SUBMIT YOUR ARTICLES - Bioscience & Engineering: An International Journal (BI...
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
SUBMIT YOUR ARTICLES - Bioscience & Engineering: An International Journal (BI...
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal calling for papers on topics related to bioscience, bioengineering, and their applications. The journal aims to bring together researchers working in various fields including agricultural technology, biochemistry, biotechnology, environmental engineering, genetics, marine science, microbiology, and pharmaceutical technology. Authors are invited to submit original, unpublished papers through the journal's online submission system or via email by January 15, 2022 for review and potential publication.
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Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Call for Papers - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
CALL FOR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
SUBMIT YOUR ARTICLES - Bioscience & Engineering: An International Journal (BI...
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
SUBMIT YOUR ARTICLES - Bioscience & Engineering: An International Journal (BI...
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal calling for papers on topics related to bioscience, bioengineering, and their applications. The journal aims to bring together researchers working in various fields including agricultural technology, biochemistry, biotechnology, environmental engineering, genetics, marine science, microbiology, and pharmaceutical technology. Authors are invited to submit original, unpublished papers through the journal's online submission system or via email by January 15, 2022 for review and potential publication.
CALL FOR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
CALL FOR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal calling for papers on topics related to bioscience, bioengineering, and their applications. The journal aims to bring together researchers working in fields like agricultural technology, biochemistry, biotechnology, environmental engineering, genetics, marine science, microbiology, and pharmaceutical technology. Authors are invited to submit original, unpublished papers through the journal's online submission system or via email by March 19, 2022 for potential publication and notification by April 18, 2022.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
SUBMIT YOUR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
PAPER SUBMISSION START NOW - Bioscience & Engineering: An International Journ...
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
CALL FOR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
Call for Research Articles - 10th International Conference on Bioinformatics ...
10th International Conference on Bioinformatics & Biosciences (BIOS 2024) is a forum for presenting new advances and research results in the field of biology to increase the understanding of all biological process. The aim of this conference is to publish all the latest and outstanding research articles in all areas of bioinformatics and Biometrics. Researchers and scientists from the fields of biology, computer science, mathematics, statistics, and physics are invited to share their developments and new techniques in the fields of Biometrics and Bioinformatics. .
DE NOVO TRANSCRIPTOME ASSEMBLY OF SOLID SEQUENCING DATA IN CUCUMIS MELO
As sequencing technologies progress, focus shifts towards solving bioinformatic challenges, of which
sequence read assembly is the first task. In the present study, we have carried out a comparison of two
assemblers (SeqMan and CLC) for transcriptome assembly, using a new dataset from Cucumis melo.
Between two assemblers SeqMan generated an excess of small, redundant contigs where as CLC generated
the least redundant assembly. Since different assemblers use different algorithms to build contigs, we
followed the merging of assemblies by CAP3 and found that the merged assembly is better than individual
assemblies and more consistent in the number and size of contigs. Combining the assemblies from different
programs gave a more credible final product, and therefore this approach is recommended for quantitative
output
Cloning and Extracellular Expression of Recombinant Tissue Plasminogen Activa...
Tissue plasminogen activator (tPA) has noteworthy application in treatment of acute myocardial
infarctions. This study focuses on expression of rt-PA using microbial systems in order to reduce cost
without compromising on quality as an alternative to commercial (rt-PA)produced by using mammalian
host systems. In the present study, Pichia pastoris X-33strain was used as a host with pICZαA expression
vector to obtain extracellular expression of full length tPA gene. Specific primers were designed in such a
way to get native tPA protein sequence in subsequent purification steps. Further, construct pICZαA-tPA
was developed and electroporated into host to achieve stablert-PA gene by achieving genome integration.
The transformants were screened for phenotypic characters.Mut+
phenotypic colony named Pichia tPA-3
showed expression of rt-PA at 66 kDa on SDS PAGE. Size Exclusion Chromatography (SEC) was
performed, resulting in product peak at same RT as reference standard. (alteplase).Cloning and expression
of rt-PA was successfully achieved in microbial system. Further process optimization at larger scales will
surely provide cost effective alternative to mammalian system forrt-PA production.
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
This study is part of a goal to investigate chemical composition, antibacterial, antifungal and antioxidant
activities of the flower buds extracts from the Algerian Polulus nigra L., which were collected from Djarifet
- mansourah at Tlemcen city in the West Northern of Algeria.
In organic extracts, tanins, flavonoïds, coumarins, alkaloids and terpenoïds were the principals secondary
metabolites identified from the flower buds of black poplar. Antibacterial and antifungal activities of
extracts were tested using agar-well diffusion method and micro-well determination of MIC assay against
eleven bacteria and two Candida species. It was found that extracts of black poplar buds exhibit
antibacterial and anticandidal activities with agar disk diffusion (7 to 43mm) and MIC methods (MIC=
90.33 µg/ml against several strains of bacteria and MIC=45.16 µg/ml against Candida albicans). The
antioxidant effect of hydroalcoholic extract was evaluated using DPPH and FRAP assays. It was showed
good and similar activity than ascorbic acid and BHA by DPPH method: IC50= 220µg/mL for
hydroethanol extract.
10th International Conference on Bioinformatics & Biosciences (BIOS 2024)
10th International Conference on Bioinformatics & Biosciences (BIOS 2024) is a forum for presenting new advances and research results in the field of biology to increase the understanding of all biological process. The aim of this conference is to publish all the latest and outstanding research articles in all areas of bioinformatics and Biometrics. Researchers and scientists from the fields of biology, computer science, mathematics, statistics, and physics are invited to share their developments and new techniques in the fields of Biometrics and Bioinformatics. .
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
The objective of this research was to design a 2.4 GHz class AB Power Amplifier (PA), with 0.18um
Semiconductor Manufacturing International Corporation (SMIC) CMOS technology by using Cadence
software, for health care applications. The ultimate goal for such application is to minimize the trade-offs
between performance and cost, and between performance and low power consumption design. This paper
introduces the design of a 2.4GHz class AB power amplifier which consists of two stage amplifiers. This
power amplifier can transmit 10dBm output power to a 50Ω load. The power added efficiency is 7.5% at
1dB compression point and the power gain is 10dB, the total power consumption is 0.135W. The
performance of the power amplifier meets the specification requirements of the desired.
Phonocardiogram Based Diagnosis Using Machine Learning : Parametric Estimatio...
The heart sound signal, Phonocardiogram (PCG) is difficult to interpret even for experienced
cardiologists. Interpretation are very subjective depending on the hearing ability of the physician. mHealth
has been the adopted approach towards quick diagnosis using mobile devices. However, it has been
challenging due to the required high quality of data, high computation load, and high-power consumption.
The aim of this paper is to diagnose the heart condition based on Phonocardiogram analysis using
Machine Learning techniques assuming limited processing power to be encapsulated later in a mobile
device. The cardiovascular system is modelled in a transfer function to provide PCG signal recording as it
would be recorded at the wrist. The signal is, then, decomposed using filter bank and the analysed using
discriminant function. The results showed that PCG with a 19 dB Signal-to-Noise-Ratio can lead to 97.33%
successful diagnosis.
NANO BIONIC SWIMMING ROBOTICS ANDAPPLICATIONS IN ENVIRONMENTALENGINEERING
As microscopic swimmers survive in nature, they have evolved unique structures and swimmingpatterns under the water, which has special advantages. The movement of bacteria at lowReynolds number (Re) environment has aroused extensive research interest. The two typical
swimming methods of bacteria are introduced in this paper. Based on this, we are inspired to design the bionic robot on a micro-scale, which is an artificial
structure that imitates the external shape, movement principle and behavior mode of organisms innature. Compared with traditional robots, nano bionic robots are easier to miniaturize[1]. Theyalso have higher maneuverability so that they can move continuously and flexibly. We expect tosimulate its motion at low Reynolds number (Re) fluids and explore complex future applicationsin dif erent fields
Consistent Relationship of Both Watercontent and Activity With Maize Seed Qua...
Seed quality can be explained using a range of indices that are acceptable within the standards set by the
International Seed Testing Association. There is a need to improve existing models to explain the wellknown variations in seed quality within and between crop species. The objective of this study was to
determine the consistency of using grain water occurrence to explain seed quality in terms of viability and
vigour in maize (Zea mays L.). Four sites were used over two seasons to grow three cultivars in order to
monitor changes in water content, water activity, dry mass and total starch observed in different cob
sections (tip, medium and bottom) at 30, 60 and 90 days after pollination. Seed quality was determined
based on the germination and vigour of physiologically mature kernels. It is concluded that grains that
seed quality is linked to the water activity and position on the cob.
Next Generation Sequencing in Detecting Oral Cancer Due to Tobacco Consumption
DNA sequence DNA Sequencing is the first step in establishing phylogenetic trees, protein structure
prediction, diagnosis of cancer, discovery of drugs and hence its importance cannot be underestimated.
DNA sequencing finds its use in the diagnosis of oral squamous cell carcinoma (OSCC). Oral Cancer is
the most common occurring malignancies in the world, especially in India where the prevalence for
smoking, Areca nut chewing coupled with a lifestyle that encourages these two activities as fashion are left
many people diagnosed with OSCC. Patients with this OSCC are more likely unaware of its side effects
and over time might suffer from facial deformity. The importance to understanding the symptoms,
prevention and treatment of oral cancer is very much essential today. In this paper, we looked at over 2000
odd papers published and look at the correlation between the next Generation DNA sequencing algorithms
(NGS) play an important role in diagnosis of OSCC. This is a further study on some of the papers which
have highlighted NGS role in OSCC Diagnosis. We did like to see a comprehensive review on the papers
published so far. In the discussion, we will see frequently mutated genes in the OSCC, recent discoveries
and OSCC treatment based on the findings.
Role of Computational Biology in Oral Science
DNA sequence Cigarette Smoking, Betel leaf chewing, and alcohol consumption are major cause of oral
cancer in Asia. The difficulty in quitting, coupled with patients’ economic conditions affects the inability to
get diagnosed early, driving death rate higher. There has been major advancement in molecular sciences,
computational biology, and other fields today, but we are not still able to pinpoint the causes of oral
cancer, also known as Squamous Cell Carcinoma (OSCC). Early detection leads to better survival rate,
therefore, education on yearly check-ups plays a vital role. Computational analysis at the genomic (DNA
sequence) can help patients with targeted cellular treatment and hopefully a cure. In this paper, we would
look at computation tools used in detecting OSCC and various analysis. Analysis includes detecting
abnormality in the cell and other molecular reactions which later morph into a cancerous cell. Later, we
investigate all computational tools or techniques from local and global sequence alignment, protein
structure, gene, functional structure analysis which help medical staff detect cancer, which in turn can help
with oral cancer treatment, prognosis and hopefully a cure.
NEXT GENERATION SEQUENCING IN DETECTING ORAL CANCER DUE TO TOBACCO CONSUMPTION
DNA sequence DNA Sequencing is the first step in establishing phylogenetic trees, protein structure
prediction, diagnosis of cancer, discovery of drugs and hence its importance cannot be underestimated.
DNA sequencing finds its use in the diagnosis of oral squamous cell carcinoma (OSCC). Oral Cancer is
the most common occurring malignancies in the world, especially in India where the prevalence for
smoking, Areca nut chewing coupled with a lifestyle that encourages these two activities as fashion are left
many people diagnosed with OSCC. Patients with this OSCC are more likely unaware of its side effects
and over time might suffer from facial deformity. The importance to understanding the symptoms,
prevention and treatment of oral cancer is very much essential today. In this paper, we looked at over 2000
odd papers published and look at the correlation between the next Generation DNA sequencing algorithms
(NGS) play an important role in diagnosis of OSCC. This is a further study on some of the papers which
have highlighted NGS role in OSCC Diagnosis. We did like to see a comprehensive review on the papers
published so far. In the discussion, we will see frequently mutated genes in the OSCC, recent discoveries
and OSCC treatment based on the findings.
ROLE OF COMPUTATIONAL BIOLOGY IN ORAL SCIENCE
DNA sequence Cigarette Smoking, Betel leaf chewing, and alcohol consumption are major cause of oral
cancer in Asia. The difficulty in quitting, coupled with patients’ economic conditions affects the inability to
get diagnosed early, driving death rate higher. There has been major advancement in molecular sciences,
computational biology, and other fields today, but we are not still able to pinpoint the causes of oral
cancer, also known as Squamous Cell Carcinoma (OSCC). Early detection leads to better survival rate,
therefore, education on yearly check-ups plays a vital role. Computational analysis at the genomic (DNA
sequence) can help patients with targeted cellular treatment and hopefully a cure. In this paper, we would
look at computation tools used in detecting OSCC and various analysis. Analysis includes detecting
abnormality in the cell and other molecular reactions which later morph into a cancerous cell. Later, we
investigate all computational tools or techniques from local and global sequence alignment, protein
structure, gene, functional structure analysis which help medical staff detect cancer, which in turn can help
with oral cancer treatment, prognosis and hopefully a cure.
Statistical Based Media Optimization and Production of Clavulanic Acid By Sol...
Statistics based optimization, Plackett–Burman design (PBD) and response surface methodology
(RSM) were employed to screen and optimize the media components for the production of
clavulanic acid from Streptomyces clavuligerus MTCC 1142, using solid state fermentation. jackfruit
seed powder was used as both the solid support and carbon source for the growth of Streptomyces
clavuligerus MTCC 1142. Based on the positive influence of the Pareto chart obtained from PBD on
clavulanic acid production, five media components – yeast extract, beef extract, sucrose, malt extract
and ferric chloride were screened. Central composite design (CCD) was employed using these five
media components- yeast extract 2.5%, beef extract 0.5%, sucrose 2.5%, malt extract 0.25% and ferric
chloride nutritional factors at three levels, for further optimization, and the second order polynomial
equation was derived, based on the experimental data. Response surface methodology showed that
the concentrations of yeast extract 2.5%, beef extract 0.5%, sucrose 2.5%, malt extract 0.25% and ferric
chloride 2.5% were the optimal levels for maximal clavulanic acid production (19.37 mg /gds) which
were validated through experiments.
A New Low-Complexity Algorithm for the Pulse Transit Time Evaluation
The pulse transit time (PTT) is a physiological parameter commonly derived from Electrocardiogram
(ECG) and Photoplethysmogram (PPG) signal. It is defined as the time taken for the arterial pulse to
travel from the heart to a peripheral site, and can be used as a direct indicator of Cardiovascular Diseases
(CVD). In this study, we propose a new low-complexity algorithm for the (PTT) estimation. The (PTT) is
calculated as the interval between the peak of the ECG R-wave and a time point on the PPG. We
considered a dataset of 37 subjects containing a simultaneous recording of the (ECG) and the (PPG). The
computation of the (PTT) consists of detecting the peak and foot points of a (PPG) and the R peak of the
(ECG) signal. Our algorithm is improved by a temporal analysis by windowing. The results obtained are
promising. The average sensitivity (SEN) and accuracy (ACC) obtained are respectively (97.5%, and
96.82%) for the detection of R peaks and (97.77%, and 97.64%) for the detection of PPG peaks. The
sensitivity (SEN) and accuracy (ACC) of the foot (PPG) detection were 98.33% and 94.14%.
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Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to)
SUBMIT YOUR PAPERS - Bioscience & Engineering: An International Journal (BIOEJ)
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PAPER SUBMISSION START NOW - Bioscience & Engineering: An International Journ...
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Call for Research Articles - 10th International Conference on Bioinformatics ...
10th International Conference on Bioinformatics & Biosciences (BIOS 2024) is a forum for presenting new advances and research results in the field of biology to increase the understanding of all biological process. The aim of this conference is to publish all the latest and outstanding research articles in all areas of bioinformatics and Biometrics. Researchers and scientists from the fields of biology, computer science, mathematics, statistics, and physics are invited to share their developments and new techniques in the fields of Biometrics and Bioinformatics. .
DE NOVO TRANSCRIPTOME ASSEMBLY OF SOLID SEQUENCING DATA IN CUCUMIS MELO
As sequencing technologies progress, focus shifts towards solving bioinformatic challenges, of which
sequence read assembly is the first task. In the present study, we have carried out a comparison of two
assemblers (SeqMan and CLC) for transcriptome assembly, using a new dataset from Cucumis melo.
Between two assemblers SeqMan generated an excess of small, redundant contigs where as CLC generated
the least redundant assembly. Since different assemblers use different algorithms to build contigs, we
followed the merging of assemblies by CAP3 and found that the merged assembly is better than individual
assemblies and more consistent in the number and size of contigs. Combining the assemblies from different
programs gave a more credible final product, and therefore this approach is recommended for quantitative
output
Cloning and Extracellular Expression of Recombinant Tissue Plasminogen Activa...
Tissue plasminogen activator (tPA) has noteworthy application in treatment of acute myocardial
infarctions. This study focuses on expression of rt-PA using microbial systems in order to reduce cost
without compromising on quality as an alternative to commercial (rt-PA)produced by using mammalian
host systems. In the present study, Pichia pastoris X-33strain was used as a host with pICZαA expression
vector to obtain extracellular expression of full length tPA gene. Specific primers were designed in such a
way to get native tPA protein sequence in subsequent purification steps. Further, construct pICZαA-tPA
was developed and electroporated into host to achieve stablert-PA gene by achieving genome integration.
The transformants were screened for phenotypic characters.Mut+
phenotypic colony named Pichia tPA-3
showed expression of rt-PA at 66 kDa on SDS PAGE. Size Exclusion Chromatography (SEC) was
performed, resulting in product peak at same RT as reference standard. (alteplase).Cloning and expression
of rt-PA was successfully achieved in microbial system. Further process optimization at larger scales will
surely provide cost effective alternative to mammalian system forrt-PA production.
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
This study is part of a goal to investigate chemical composition, antibacterial, antifungal and antioxidant
activities of the flower buds extracts from the Algerian Polulus nigra L., which were collected from Djarifet
- mansourah at Tlemcen city in the West Northern of Algeria.
In organic extracts, tanins, flavonoïds, coumarins, alkaloids and terpenoïds were the principals secondary
metabolites identified from the flower buds of black poplar. Antibacterial and antifungal activities of
extracts were tested using agar-well diffusion method and micro-well determination of MIC assay against
eleven bacteria and two Candida species. It was found that extracts of black poplar buds exhibit
antibacterial and anticandidal activities with agar disk diffusion (7 to 43mm) and MIC methods (MIC=
90.33 µg/ml against several strains of bacteria and MIC=45.16 µg/ml against Candida albicans). The
antioxidant effect of hydroalcoholic extract was evaluated using DPPH and FRAP assays. It was showed
good and similar activity than ascorbic acid and BHA by DPPH method: IC50= 220µg/mL for
hydroethanol extract.
10th International Conference on Bioinformatics & Biosciences (BIOS 2024)
10th International Conference on Bioinformatics & Biosciences (BIOS 2024) is a forum for presenting new advances and research results in the field of biology to increase the understanding of all biological process. The aim of this conference is to publish all the latest and outstanding research articles in all areas of bioinformatics and Biometrics. Researchers and scientists from the fields of biology, computer science, mathematics, statistics, and physics are invited to share their developments and new techniques in the fields of Biometrics and Bioinformatics. .
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
The objective of this research was to design a 2.4 GHz class AB Power Amplifier (PA), with 0.18um
Semiconductor Manufacturing International Corporation (SMIC) CMOS technology by using Cadence
software, for health care applications. The ultimate goal for such application is to minimize the trade-offs
between performance and cost, and between performance and low power consumption design. This paper
introduces the design of a 2.4GHz class AB power amplifier which consists of two stage amplifiers. This
power amplifier can transmit 10dBm output power to a 50Ω load. The power added efficiency is 7.5% at
1dB compression point and the power gain is 10dB, the total power consumption is 0.135W. The
performance of the power amplifier meets the specification requirements of the desired.
Phonocardiogram Based Diagnosis Using Machine Learning : Parametric Estimatio...
The heart sound signal, Phonocardiogram (PCG) is difficult to interpret even for experienced
cardiologists. Interpretation are very subjective depending on the hearing ability of the physician. mHealth
has been the adopted approach towards quick diagnosis using mobile devices. However, it has been
challenging due to the required high quality of data, high computation load, and high-power consumption.
The aim of this paper is to diagnose the heart condition based on Phonocardiogram analysis using
Machine Learning techniques assuming limited processing power to be encapsulated later in a mobile
device. The cardiovascular system is modelled in a transfer function to provide PCG signal recording as it
would be recorded at the wrist. The signal is, then, decomposed using filter bank and the analysed using
discriminant function. The results showed that PCG with a 19 dB Signal-to-Noise-Ratio can lead to 97.33%
successful diagnosis.
NANO BIONIC SWIMMING ROBOTICS ANDAPPLICATIONS IN ENVIRONMENTALENGINEERING
As microscopic swimmers survive in nature, they have evolved unique structures and swimmingpatterns under the water, which has special advantages. The movement of bacteria at lowReynolds number (Re) environment has aroused extensive research interest. The two typical
swimming methods of bacteria are introduced in this paper. Based on this, we are inspired to design the bionic robot on a micro-scale, which is an artificial
structure that imitates the external shape, movement principle and behavior mode of organisms innature. Compared with traditional robots, nano bionic robots are easier to miniaturize[1]. Theyalso have higher maneuverability so that they can move continuously and flexibly. We expect tosimulate its motion at low Reynolds number (Re) fluids and explore complex future applicationsin dif erent fields
Consistent Relationship of Both Watercontent and Activity With Maize Seed Qua...
Seed quality can be explained using a range of indices that are acceptable within the standards set by the
International Seed Testing Association. There is a need to improve existing models to explain the wellknown variations in seed quality within and between crop species. The objective of this study was to
determine the consistency of using grain water occurrence to explain seed quality in terms of viability and
vigour in maize (Zea mays L.). Four sites were used over two seasons to grow three cultivars in order to
monitor changes in water content, water activity, dry mass and total starch observed in different cob
sections (tip, medium and bottom) at 30, 60 and 90 days after pollination. Seed quality was determined
based on the germination and vigour of physiologically mature kernels. It is concluded that grains that
seed quality is linked to the water activity and position on the cob.
Next Generation Sequencing in Detecting Oral Cancer Due to Tobacco Consumption
DNA sequence DNA Sequencing is the first step in establishing phylogenetic trees, protein structure
prediction, diagnosis of cancer, discovery of drugs and hence its importance cannot be underestimated.
DNA sequencing finds its use in the diagnosis of oral squamous cell carcinoma (OSCC). Oral Cancer is
the most common occurring malignancies in the world, especially in India where the prevalence for
smoking, Areca nut chewing coupled with a lifestyle that encourages these two activities as fashion are left
many people diagnosed with OSCC. Patients with this OSCC are more likely unaware of its side effects
and over time might suffer from facial deformity. The importance to understanding the symptoms,
prevention and treatment of oral cancer is very much essential today. In this paper, we looked at over 2000
odd papers published and look at the correlation between the next Generation DNA sequencing algorithms
(NGS) play an important role in diagnosis of OSCC. This is a further study on some of the papers which
have highlighted NGS role in OSCC Diagnosis. We did like to see a comprehensive review on the papers
published so far. In the discussion, we will see frequently mutated genes in the OSCC, recent discoveries
and OSCC treatment based on the findings.
Role of Computational Biology in Oral Science
DNA sequence Cigarette Smoking, Betel leaf chewing, and alcohol consumption are major cause of oral
cancer in Asia. The difficulty in quitting, coupled with patients’ economic conditions affects the inability to
get diagnosed early, driving death rate higher. There has been major advancement in molecular sciences,
computational biology, and other fields today, but we are not still able to pinpoint the causes of oral
cancer, also known as Squamous Cell Carcinoma (OSCC). Early detection leads to better survival rate,
therefore, education on yearly check-ups plays a vital role. Computational analysis at the genomic (DNA
sequence) can help patients with targeted cellular treatment and hopefully a cure. In this paper, we would
look at computation tools used in detecting OSCC and various analysis. Analysis includes detecting
abnormality in the cell and other molecular reactions which later morph into a cancerous cell. Later, we
investigate all computational tools or techniques from local and global sequence alignment, protein
structure, gene, functional structure analysis which help medical staff detect cancer, which in turn can help
with oral cancer treatment, prognosis and hopefully a cure.
NEXT GENERATION SEQUENCING IN DETECTING ORAL CANCER DUE TO TOBACCO CONSUMPTION
DNA sequence DNA Sequencing is the first step in establishing phylogenetic trees, protein structure
prediction, diagnosis of cancer, discovery of drugs and hence its importance cannot be underestimated.
DNA sequencing finds its use in the diagnosis of oral squamous cell carcinoma (OSCC). Oral Cancer is
the most common occurring malignancies in the world, especially in India where the prevalence for
smoking, Areca nut chewing coupled with a lifestyle that encourages these two activities as fashion are left
many people diagnosed with OSCC. Patients with this OSCC are more likely unaware of its side effects
and over time might suffer from facial deformity. The importance to understanding the symptoms,
prevention and treatment of oral cancer is very much essential today. In this paper, we looked at over 2000
odd papers published and look at the correlation between the next Generation DNA sequencing algorithms
(NGS) play an important role in diagnosis of OSCC. This is a further study on some of the papers which
have highlighted NGS role in OSCC Diagnosis. We did like to see a comprehensive review on the papers
published so far. In the discussion, we will see frequently mutated genes in the OSCC, recent discoveries
and OSCC treatment based on the findings.
ROLE OF COMPUTATIONAL BIOLOGY IN ORAL SCIENCE
DNA sequence Cigarette Smoking, Betel leaf chewing, and alcohol consumption are major cause of oral
cancer in Asia. The difficulty in quitting, coupled with patients’ economic conditions affects the inability to
get diagnosed early, driving death rate higher. There has been major advancement in molecular sciences,
computational biology, and other fields today, but we are not still able to pinpoint the causes of oral
cancer, also known as Squamous Cell Carcinoma (OSCC). Early detection leads to better survival rate,
therefore, education on yearly check-ups plays a vital role. Computational analysis at the genomic (DNA
sequence) can help patients with targeted cellular treatment and hopefully a cure. In this paper, we would
look at computation tools used in detecting OSCC and various analysis. Analysis includes detecting
abnormality in the cell and other molecular reactions which later morph into a cancerous cell. Later, we
investigate all computational tools or techniques from local and global sequence alignment, protein
structure, gene, functional structure analysis which help medical staff detect cancer, which in turn can help
with oral cancer treatment, prognosis and hopefully a cure.
Statistical Based Media Optimization and Production of Clavulanic Acid By Sol...
Statistics based optimization, Plackett–Burman design (PBD) and response surface methodology
(RSM) were employed to screen and optimize the media components for the production of
clavulanic acid from Streptomyces clavuligerus MTCC 1142, using solid state fermentation. jackfruit
seed powder was used as both the solid support and carbon source for the growth of Streptomyces
clavuligerus MTCC 1142. Based on the positive influence of the Pareto chart obtained from PBD on
clavulanic acid production, five media components – yeast extract, beef extract, sucrose, malt extract
and ferric chloride were screened. Central composite design (CCD) was employed using these five
media components- yeast extract 2.5%, beef extract 0.5%, sucrose 2.5%, malt extract 0.25% and ferric
chloride nutritional factors at three levels, for further optimization, and the second order polynomial
equation was derived, based on the experimental data. Response surface methodology showed that
the concentrations of yeast extract 2.5%, beef extract 0.5%, sucrose 2.5%, malt extract 0.25% and ferric
chloride 2.5% were the optimal levels for maximal clavulanic acid production (19.37 mg /gds) which
were validated through experiments.
A New Low-Complexity Algorithm for the Pulse Transit Time Evaluation
The pulse transit time (PTT) is a physiological parameter commonly derived from Electrocardiogram
(ECG) and Photoplethysmogram (PPG) signal. It is defined as the time taken for the arterial pulse to
travel from the heart to a peripheral site, and can be used as a direct indicator of Cardiovascular Diseases
(CVD). In this study, we propose a new low-complexity algorithm for the (PTT) estimation. The (PTT) is
calculated as the interval between the peak of the ECG R-wave and a time point on the PPG. We
considered a dataset of 37 subjects containing a simultaneous recording of the (ECG) and the (PPG). The
computation of the (PTT) consists of detecting the peak and foot points of a (PPG) and the R peak of the
(ECG) signal. Our algorithm is improved by a temporal analysis by windowing. The results obtained are
promising. The average sensitivity (SEN) and accuracy (ACC) obtained are respectively (97.5%, and
96.82%) for the detection of R peaks and (97.77%, and 97.64%) for the detection of PPG peaks. The
sensitivity (SEN) and accuracy (ACC) of the foot (PPG) detection were 98.33% and 94.14%.
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
This study is part of a goal to investigate chemical composition, antibacterial, antifungal and antioxidant
activities of the flower buds extracts from the Algerian Polulus nigra L., which were collected from Djarifet
- mansourah at Tlemcen city in the West Northern of Algeria.
In organic extracts, tanins, flavonoïds, coumarins, alkaloids and terpenoïds were the principals secondary
metabolites identified from the flower buds of black poplar. Antibacterial and antifungal activities of
extracts were tested using agar-well diffusion method and micro-well determination of MIC assay against
eleven bacteria and two Candida species. It was found that extracts of black poplar buds exhibit
antibacterial and anticandidal activities with agar disk diffusion (7 to 43mm) and MIC methods (MIC=
90.33 µg/ml against several strains of bacteria and MIC=45.16 µg/ml against Candida albicans). The
antioxidant effect of hydroalcoholic extract was evaluated using DPPH and FRAP assays. It was showed
good and similar activity than ascorbic acid and BHA by DPPH method: IC50= 220µg/mL for
hydroethanol extract.
NEW SEQUENCE ALIGNMENT ALGORITHM USING AI RULES AND DYNAMIC SEEDS
DNA sequence alignment is important today as it is usually the first step in finding gene mutation,
evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one
recent example. There are many sequencing algorithms developed over the past decades but the sequence
alignment using expert systems is quite new. To find DNA sequence alignment, dynamic programming was
used initially. Later faster algorithms used small DNA sequence length of fixed size to find regions of
similarity, and then build the final alignment using these regions. Such systems were not sensitive but were
fast. To improve the sensitivity, we propose a new algorithm which is based on finding maximal matches
between two sequences, find seeds between them, employ rules to find more seeds of varying length, and
then employ a new stitching algorithm, and weighted seeds to solve the problem.
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
The objective of this research was to design a 2.4 GHz class AB Power Amplifier (PA), with 0.18um
Semiconductor Manufacturing International Corporation (SMIC) CMOS technology by using Cadence
software, for health care applications. The ultimate goal for such application is to minimize the trade-offs
between performance and cost, and between performance and low power consumption design. This paper
introduces the design of a 2.4GHz class AB power amplifier which consists of two stage amplifiers. This
power amplifier can transmit 10dBm output power to a 50Ω load. The power added efficiency is 7.5% at
1dB compression point and the power gain is 10dB, the total power consumption is 0.135W. The
performance of the power amplifier meets the specification requirements of the desired.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering.
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal addressing impacts and challenges of bioscience, bioengineering, and applications. It invites researchers and practitioners to submit papers on topics including agriculture, biochemistry, biotechnology, environmental engineering, genetics, microbiology, and more. Authors should submit papers through the online submission system or via email by September 10, 2023 for notification by October 3, 2023 and final manuscript due by October 10, 2023.
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Call for Research Articles - 10th International Conference on Bioinformatics ...
Call for Research Articles - 10th International Conference on Bioinformatics ...
DE NOVO TRANSCRIPTOME ASSEMBLY OF SOLID SEQUENCING DATA IN CUCUMIS MELO
DE NOVO TRANSCRIPTOME ASSEMBLY OF SOLID SEQUENCING DATA IN CUCUMIS MELO
Cloning and Extracellular Expression of Recombinant Tissue Plasminogen Activa...
Cloning and Extracellular Expression of Recombinant Tissue Plasminogen Activa...
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
10th International Conference on Bioinformatics & Biosciences (BIOS 2024)
10th International Conference on Bioinformatics & Biosciences (BIOS 2024)
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
Phonocardiogram Based Diagnosis Using Machine Learning : Parametric Estimatio...
Phonocardiogram Based Diagnosis Using Machine Learning : Parametric Estimatio...
NANO BIONIC SWIMMING ROBOTICS ANDAPPLICATIONS IN ENVIRONMENTALENGINEERING
NANO BIONIC SWIMMING ROBOTICS ANDAPPLICATIONS IN ENVIRONMENTALENGINEERING
Consistent Relationship of Both Watercontent and Activity With Maize Seed Qua...
Consistent Relationship of Both Watercontent and Activity With Maize Seed Qua...
Next Generation Sequencing in Detecting Oral Cancer Due to Tobacco Consumption
Next Generation Sequencing in Detecting Oral Cancer Due to Tobacco Consumption
NEXT GENERATION SEQUENCING IN DETECTING ORAL CANCER DUE TO TOBACCO CONSUMPTION
NEXT GENERATION SEQUENCING IN DETECTING ORAL CANCER DUE TO TOBACCO CONSUMPTION
Statistical Based Media Optimization and Production of Clavulanic Acid By Sol...
Statistical Based Media Optimization and Production of Clavulanic Acid By Sol...
A New Low-Complexity Algorithm for the Pulse Transit Time Evaluation
A New Low-Complexity Algorithm for the Pulse Transit Time Evaluation
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ALGERIAN POPULUS NIGRA L. BUDS EX...
NEW SEQUENCE ALIGNMENT ALGORITHM USING AI RULES AND DYNAMIC SEEDS
NEW SEQUENCE ALIGNMENT ALGORITHM USING AI RULES AND DYNAMIC SEEDS
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
LOW POWER CLASS AB SI POWER AMPLIFIER FOR WIRELESS MEDICAL SENSOR NETWORK
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ)
Bioscience & Engineering: An International Journal (BIOEJ)
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Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
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www.agostodourado.com
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Bioscience & Engineering: An International Journal (BIOEJ)
- 1. Bioscience & Engineering: An International Journal (BIOEJ) ISSN : 2349 - 848X https://airccse.com/bioej/index.html Call for papers Bioscience & Engineering: An International Journal (BIOEJ) is a peer-reviewed, open access journal that addresses the impacts and challenges of Bioscience, Bioengineering and Applications. The journal documents practical and theoretical results which make a fundamental contribution for the development of Bioscience & Engineering. This journal aims to bring together researchers and practitioners in all Bioscience & Engineering aspects, including (but not limited to) Topics of Interest Agriculture and food Agricultural Technology Anatomy and morphology Behavioral Sciences Biochemical Engineering Biochemistry Bio-fermentation Technology Bioinformatics Biomedicine Bioscience Engineering Biotechnology Entomology Environmental Engineering Environmental Technology Food Science & Technology Forestry Genetics Geomicrobiology Health Informatics Immunotechnology Marine Science and Technology Microbiology Molecular Biology of Plants Pharmaceutical Technology Zoo physiology
- 2. Paper Submission Authors are invited to submit papers for this journal through Submission system or E-mail: bioej@airccse.com. Submissions must be original and should not have been published previously or be under consideration for publication while being evaluated for this Journal. Important Dates Submission Deadline : June 10,2023 Notification : July 10, 2023 Final Manuscript Due : July 17, 2023 Publication Date: Determined by the Editor-in-Chief Contact Us: Here's where you can reach us : bioej@airccse.com or bioejsecratry@yahoo.com SUBMISSION URL : https://airccse.com/submission/home.html Other Related Journal International Journal of Biomedical Engineering and Science (IJBES) https://airccse.com/bioej/index.html Agricultural Science: An International journal (AGRIJ) https://airccse.com/agrij/index.html