This document discusses beta blockers and diuretics used in the treatment of hypertension. It describes the mechanisms and sites of action of various beta blockers including selective beta-1 blockers like atenolol and metoprolol, non-selective blockers like propranolol, and alpha-beta blockers like labetalol. It also discusses the pharmacokinetics and uses of specific beta blockers. The document then discusses thiazide and loop diuretics, their mechanisms of action in inhibiting sodium transport in the kidney, and their toxicities which can include hypokalemia, hyperglycemia, and hypomagnesemia.