The Fundación General CSIC, established in 2008, focuses on fostering public-private partnerships for scientific research to address societal challenges and promote sustainable development. The foundation aims to stimulate innovative research in strategic areas, including biomedicine and aging, while encouraging collaboration among various stakeholders in Spain and beyond. Funding and support are provided for high-impact research projects through an application process involving external evaluations.

1. Fundación General CSIC
José Luis de Miguel
Deputy Director
Fundación
General CSIC
Fundación
General CSIC

2. What we are
Private foundation created in 2008
on the initiative of the Spanish
National Research Council (CSIC)
Fundación
General CSIC
Fundación General CSIC

3. Honorary President
D. Federico Mayor Zaragoza
President
D. Emilio Lora-Tamayo D’Ocón
(CSIC President)
Who we are
Fundación
General CSIC
Fundación General CSIC

4. We want the main actors in economic and social
development to be committed to the challenges
facing humanity, the goals of society, our common
causes, and the needs of future generations, as part
of the social responsibility of the business world
and an opportunity to build a future for their
own expansion
What we do
... we look for and promote public-private
partnerships for scientific research ...
Fundación
General CSIC
Fundación General CSIC

5. How we do it Raising awareness
among the private
Identifying areas of
research suitable
Taking direct action
to promote public
sector to public for public-private
research
research partnership
Fundación
General CSIC
Fundación General CSIC

6. The tree of science is not a species that grows in
isolation, separate from the world and its surrounding
environment; it is rooted in society and needs to be
nurtured by it. However, it repays this care and effort
in the form of human welfare and progress
Sponsorship
(non profit)
How we
finance it Other
Fundación
General CSIC
Research
Industry
(for profit)
Fundación
General CSIC
Fundación General CSIC

7. we are here ...
Where we are
Príncipe de Vergara 9 - 2º Dcha.
Madrid 28001
www.fgcsic.es
Fundación
... but we act in Spain ...
General CSIC
and also in other countries
Fundación General CSIC

8. Research Biomedicine,
and new threatened species ageing, disability and illness prosthetics,
alternatives physical
for the substitutes,
new materials,
protection and
dependence,
conservation isolation,
of threatened economic
species impact, etc.
In what
Energy, water, High-risk
migrations, innovative
climate change, projects
cultural in under-
fusion, town explored
and country fields.
planning, Generators of
sustainability, paradigms
agriculture,
biodiversity, etc.
human ecology and
Frontiers
development
Fundación
General CSIC
Fundación General CSIC

9. f
Funding
r&d
Research
With what
r
Relationship
a
Analysis
i
Information
Fundación
General CSIC
Fundación General CSIC

10. r&d Research
Ambitious research
projects, involving Public
research groups SME entities
from different CSIC
ns
institutions and
tio
da
subject areas, and
un
Project
financial agents,
fo
public and private, investors
with economic hospitals
interests in the
networking
results of research industry
universities
Through its project networking initiative, the FGCSIC
Fundación
aims to harmonise the interests of businesses, investment
General CSIC groups, or individuals, with the social, economic and
technological challenges that require research, while
bearing in mind the interests of the private sponsors
Fundación General CSIC

11. Fundación General CSIC
Calls for proposals open to all public R&D institutions, to fund
high-impact
What innovative
trans-disciplinary
research projects on topics defined in the Foundation’s
strategic lines
Provide for dissemination and outreach activities
Promote the transfer of results to industry
Fundación
General CSIC
Duration: 3 years.
Fundación General CSIC

12. Fundación General CSIC
Foster innovative research in areas of
interest to the Foundation
Why By stimulating new areas of research, new
approaches and paradigms, ...
Becoming a nucleating center for the
interests of the stakeholders in the Spanish
R&D & Industry System
With the aim of facilitating the opening of new
lines of public-private funding of research
Fundación
General CSIC
Fundación General CSIC

13. Fundación General CSIC
Characteristics of the call - Application
Two phases:
How -- Expressions of interest: succinct emphasis
on the idea
-- Final draft: projects fully developed and
documented
Characteristics of the call - Evaluation
-- Commission of external experts
(International)
Fundación
General CSIC
Fundación General CSIC

14. ce Proyectos Cero 1.1 M€
So far 2010
r o Threatened species 5 Projects
2011
ce Proyectos Cero 1.1 M€
r o Ageing 5 Projects
Fundación
General CSIC
Fundación General CSIC

15. 2010
ce Proyectos Cero 1.1 M€
r o Threatened species 5 Projects
Unveiling the Iberian lynx genome Do all endangered species hold the same Disease mitigation in declining amphibians
value? Origin and conservation of living fos- populations
sils of flowering plants endemic to Spain
José Antonio Godoy Pablo Vargas Jaime Bosch.
Estación Biológica de Doñana - CSIC Real Jardín Botánico - CSIC Museo Nacional de Ciencias Naturales - CSIC
• Centro de Investigaciones Biológicas - CSIC • Universidad de Valencia • Imperial College London (United Kingdom)
• Centro Nacional de Genotipado • Institute of Zoology (United Kingdom)
• Centre de Regulació Genòmica
STEPPE-AHEAD: Steppe-land birds, agri- Action plan for viability proposals of the en-
culture practices and economic viability: dangered limpet, Patella ferruginea
towards the conservation of threatened spe-
cies in humanised landscapes
Lluís Brotons Annie Machordom
Centre Tecnològic Forestal de Catalunya Museo Nacional de Ciencias Naturales - CSIC
• Universitat de Lleida • institut de Recerca i Tecnología Agroàlimentaries
• Universitat Autónoma de Barcelona
• Instituto de Investigación en Recursos Cinegéticos
- CSIC
Fundación
General CSIC
Fundación General CSIC

16. We live longer
Life expectancy at birth
100
Women
Average
90 Men
80
70
60
Spain
50
1950-55 1980-85 2010-15 2040-45 2070-75 2100-05
Period (years)
Fundación
General CSIC
Fundación General CSIC

17. Human populations have aged.
Especially those in more developed countries ... and the trend is to a greater aging of the population
1950 2010 2050
Men Women Men Women
Men Women 105 105
105
100 100 100
90 90 90
80 80 80
70 70 70
60 60 60
Años
Años
Años
50 50 50
40 40 40
30 30 30
20 20 20
10 10 10
0 0 0
5 0 5 5 0 5 5 0 5
% of total % of total
% of total
Fundación
General CSIC
Spain
Fundación General CSIC

18. The aging of the population poses:
• New social, technological, economic and health challenges
• New needs, new markets
Live longer but, above all, live better
Any solution to the unknown future can only come from research ...
...a long distance race, without shortcuts
Fundación
General CSIC
Fundación General CSIC

19. Ageing is one of FGCSIC’s strategic lines ageing, disability and illness
Biomedicine,
prosthetics,
physical
substitutes,
new materials,
dependence,
threatened species isolation,
Research economic
and new impact, etc.
alternatives
for the
protection and
conservation
of threatened
species
Energy, water, High-risk
migrations, innovative
climate change, projects
cultural in under-
fusion, town explored
and country fields.
planning, Generators of
sustainability, paradigms
agriculture, human ecology and
Frontiers
development
biodiversity, etc.
Fundación
General CSIC
Fundación General CSIC

20. Fundación General CSIC
How (a story)
Other than researching in the field of
Health and Life Sciences, what are
researchers doing to address Ageing as a
societal challenge?
Fundación
General CSIC
Fundación General CSIC

21. Fundación General CSIC
5.000
a
Ageing total
4.000
Analysis
Biomedicine
3.000
2.000 Fundamental
Biology
Neuroscience
1.000 and Behaviour
Technology watch and
competitive intelligence 0
1995 1997 1999 2001 2003 2005 2007 2009
Fundación
General CSIC Spanish scientific publications on Ageing
Fundación General CSIC

22. Fundación General CSIC
5.000 250
Ageing total
Biology
4.000
Biomedicine
3.000 200 Social Science
Fundamental
2.000
Biology Law
Neuroscience Nutrition
1.000 and Behaviour 150
Robotics and Computer
0
1995 1997 1999 2001 2003 2005 2007 2009 Chemistry
100
Engineering
50
0
1995 1997 1999 2001 2003 2005 2007 2009
Fundación
General CSIC Spanish scientific publications on Ageing: Emerging Areas
Fundación General CSIC

23. 2011
ce Proyectos Cero
r o Ageing
Thematic areas
Psycho-social research
-- Social impact of ageing
-- Impact of ageing
-- Healthy ageing
Technology research
-- Telemedicine
-- Intelligent and advanced prosthetics
-- New biocompatible materials
-- Home automation and robotics for ageing
Fundación
General CSIC -- CTs against ageing
-- Social networks and ageing
Fundación
General CSIC
Allocation of 1.1 M€ for research projects
Fundación General CSIC

24. 2011
ce Proyectos Cero
r o Ageing
Characteristics of the Call
• Open to all public R&D institutions
• At least one of the groups taking part in the project must belong to the CSIC
• Allocation: 1,1 M€
• Duration: up to 3 years
• Proposals in two phases:
Expressions of interest: 15 january / 28 february 2011
Final Draft: 15 april / 31 may 2011
• External scientific evaluation (International), with the collaboration of the National
Agency for Assessment and Planning (ANEP)
Fundación
General CSIC
Fundación General CSIC

25. 2011
ce Proyectos Cero
r o Ageing
Proposals submitted
Technological
Full Drafts 9
Full Drafts 6
Psycho-social
Expressions Expressions
of Interest 25 of Interest 22
Fundación
General CSIC
Fundación General CSIC

26. 2011
ce Proyectos Cero
r o Ageing
Funded projects
Worthplay. Human-computer games for positive ageing • Universidad Pompeu Fabra
Josep Blat. U. Pompeu Fabra • Inst. Investigación de Inteligencia Artificial (CSIC)
• Univ. Dundee (Escocia)
The objective of this project is to investigate the design, development and evaluation of an online game
prototype for the elderly, quality games that really contribute to active aging and to improve their physi-
cal and psychosocial wellbeing.
Josep Blat
Biomaterials for modulation of inflammation that causes Age Related • Inst. Cerámica y Vidrio (CSIC)
Macular Degeneration (BIOAMD) • Inst. Nacional de Engenharia Biomédica
Eva Chinarro. Instituto de Cerámica y Vidrio (CSIC) (Portugal)
The ultimate objective of this project is to develop a novel class of hybrid biomaterials with integrated
bioactivity to counteract some of the processes which contribute to systemic and tissue ageing of the
eye. This biomaterial will be capable of modulating the extra cellular and connective tissue environment
Eva Chinarro in the eye to prevent and control the inflammatory events that occurs during the progression of AMD.
Brain Computer Interface (BCI) for cognitive training and domotic as- • Universidad de Valladolid
sistance against the effects of ageing • Centro de Automática y Robótica (CSIC-UPM)
Roberto Hornero. U. Valladolid • Centro de Referencia Estatal de Discapacidad y
Dependencia
The project proposes the use of BCI systems that translate user intentions into control commands,
as cognitive training tool that helps to prevent the effects of aging and also allows for the control of
electronic and home-automation devices at home
Fundación
General CSIC Roberto Hornero
Fundación General CSIC

27. 2011
ce Proyectos Cero
r o Ageing
Funded projects
Pensions and Education: Combined Effects on inter and intragenera- • Universidad de Barcelona
tional redistribution • Inst. Bienes y Políticas Públicas (CSIC)
• Univ. Autónoma de Barcelona
Concepció Patxot. U. Barcelona.
This project addresses, from a multidisciplinary perspective, the analysis of the effects on inter and
intra-generational distribution of income, that produce the educational system and the pension system
Josep Blat in a context of demographic aging.
Concepció Patxot
Active aging, citizenship and participation: assessing the aspirations, • Universidad Autónoma de Barcelona
needs and strategies related to autonomy and empowerment of old • Inst. Estudios Sociales Avanzados (CSIC)
and new generations of elderly people in Spain • Inst. Economía, Geografía y Demografía (CSIC)
Joan Subirats. U. Autónoma de Barcelona
• Fundació Institut Català de l’Envelliment
The project aims at establishing proposals to strengthen the participation of the elderly in the process • Univ. Girona
of developing and implementing public policies to promote active aging. All this from recognizing the
Joan Subirats heterogeneity and diversity of this group, from the incorporation of significant practices in this regard • Fundació Doctor Robert
and from the use of information and communication technologies.
Fundación
General CSIC
Fundación General CSIC

28. Fundación
General CSIC
Fundación General CSIC

29. FGCSIC Report on R&D on aging
• Situation of an aging population in Spain
• Scientific and technological production on aging
• More prolific knowledge areas
• Emergent knowledge areas
• Spanish R&D performing organizations with research lines of
potential interest to aging
Fundación
General CSIC
Fundación General CSIC

30. a
Analysis
33.700
Searching for Ageing
Defining search
documents in
terms
databases
1.983
Subset of
Extracting e-mail
documents
addresses of
fgcsic
related to the 49.358
authors
topic analyzed
Energy in the Automotive
indusry
Surveys Personalizing
email with the
recipient’s
name and the
Filling the survey
on the specific
web-site
3.884
documents found 937
Surveys sent
Analysis of
responses Surveys received
Completed surveys
Fundación
General CSIC
Fundación General CSIC

31. FGCSIC scientific prospective survey on aging
Distribution
number of
questionnaires
500+
500-200
200-100
100-50
50-20
20-10
<10
Fundación
General CSIC
Fundación General CSIC

32. FGCSIC scientific prospective survey on aging
Future trends
Grupo Temática sube baja Total Tendencia
Regeneracion 23 1 24
Soluciones Células troncales 15 3 18
Tratamientos farmacológicos 5 12 17
Investigación Bases moleculares, celulares y evolutivas 14 8 22
Básica Genética del envejecimiento 9 5 14
Cuidado de mayores 32 12 44
Cuidados
Alimentación 12 5 17
Prevención Varias 12 9 21
Deterioro cognitivo 24 6 30
Cardiovascular 16 6 22
Problemas
Enfermedades relacionadas con la edad 13 8 21
asociados con el
Alzheimer 11 8 19
envejecimiento
Neurodegeneración 13 3 16
Cancer 9 4 13
Modelo social 20 7 27
Social
Trabajo 6 7 13
Interfaz cerebro-ordenador 19 0 19
Telemedicina 18 0 18
Tecnologías de la información y las comunicaciones 12 3 15
Tecnológicos Prótesis 10 3 13
Domótica 12 1 13
Robotica 12 0 12
Urbanismo 12 1 13
Fundación Vivir más Aumento de la esperanza de vida 17 33 50
General CSIC
Vivir mejor Retraso del envejecimiento 23 3 26
Fundación General CSIC

33. Protagonismo y participación activa de las
personas mayores en nuestra sociedad.
Área de Acción Social. Obra Social la Caixa.
La historia del Programa de Personas Mayores de la Obra Social
«la Caixa» se inicia en los años setenta, cuando se ponen en
marcha los primeros centros de personas mayores. Hoy este
programa es una de las líneas de actuación estratégicas de la
institución.
«Desde la Obra Social “la Caixa”
propiciamos la interacción de los
mayores con la ciudadanía a todos los
Fundación
General CSIC niveles»
Jaume Lanaspa. Director Ejecutivo de la Obra
Social «la Caixa» y Director General de Fundación
«la Caixa»
Fundación General CSIC

34. FGCSIC has produced a proposal to the private sector based on
projects with high scientific research content
A proposal based on transformative research fits better non
for profit organizations, which believe in the power of scientific
research as a means to transform society in the long run
It may also be appealing to large corporations who are willing to
diversify their R&D portfolio with “high risk/high reward” projects
Fundación
General CSIC
Fundación General CSIC

35. Provide some conditions for encouraging transformative
research
-- In the features of the call (multidisciplinary, oriented towards
solving societal challenges)
-- Thru the peer-review process
-- Easy to manage extra money: providing the flexibility and
discretionary time
-- Accompanying the researchers
Fundación
General CSIC
Fundación General CSIC

36. Fundación
General CSIC
Tha n k you!
We want the main actors in economic and social development to be
committed to the challenges facing humanity, the goals of society, our
common causes, and the needs of future generations, as part of the
social responsibility of the business world and an opportunity to build
a future for their own expansion