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ANTI-AMEBIC DRUGS
DR.FOUZIA
ANTI-AMEBIC DRUGS
1-Metronidazole
2-Tinidazole
3-Iodoquinol
4-Diloxanide Furoate
5-Paromomycin sulfate
6-Emetine and dihydro-emetine
METRONIDAZOLE
It is drug of choice for amebiasis.
It kills trophozoites but not cysts
Mechanism of action:
It is reduced in protozoa and bacteria and reactive reduction products are
responsible for antiprotozoal and antibacterial activity.
Clinical uses:
Amebiasis
Giardiasis
Trichomoniasis
METRONIDAZOLE
Adverse effect:
1-Nausea
2-Headache
3-Dry mouth
4-Metallic taste in mouth
5-Vomiting
6-Diarrhea
7-Insomnia
8-Weakness
9-Paresthesia, encephalopathy, neurotpenia
10-Dizziness
11-Dysuria

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