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Anesthesia for ophthalmic surgery
and complication
Prepared by:- Gammachis Akuma (Anesthetist)
February, 2023
2/20/2023 1
Outline
• Specific ophthalmic conditions and procedures
• Effects of commonly used anesthetic agents and
techniques on the eyes
• Preoperative assessment of ophthalmic patients
• Anesthesia for elective vs emergency (traumatic)
ophthalmic surgery
• General anesthesia
• Sedation techniques/MAC
• Regional anesthesia (preparation of LA, blocks,
infiltration, topical and complication)
2/20/2023 2
Objective
• At the end of this lesson participants will be
able:-
– To identify effect of anesthetic agent on IOP
– To describe systemic effect of commonly used
ophthalmic drugs
– To perform regional block for ophthalmic surgery
– To identify indications for providing regional
anesthesia for patients undergoing eye surgery.
– To describe complications that may result from
regional anesthesia for eye blocks.
2/20/2023 3
SPECIFIC OPHTHALMIC CONDITIONS
AND PROCEDURES
2/20/2023 4
2/20/2023 5
1. Cataract extraction
• Cataracts are opacities of the crystalline lens of
the eye.
• Cataract surgery incurs little risk since physiologic
stress is minimal and no blood loss or fluid shifts
occur
• No benefits derive from routine testing before
cataract surgery
2/20/2023 6
Cataract cont…
• Etiology may be varied
– Hereditary cataracts.
– Syndromes may be associated with cataracts.
– Metabolic causes
– Blunt or penetrating trauma
– Inflammation
– Tumors, such as retinoblastoma.
– Intrauterine infection
– Radiation for leukemia might cause cataracts.
– Chronic steroid use
2/20/2023 7
Cataract cont..
• Treatment involves surgical implantation of an
intraocular lens, which may need to be done
very early
• The procedure takes about 30 - 60 minutes,
but complications can be more frequent in
children,
• depending on the density of the cataract, the patient’s
cooperation, and the skill and experience of surgeons.
2/20/2023 8
2. Vitreoretinal surgery
• Vitreoretinal surgery is performed for the repair
of a detached retina
– related to a defect in the retina, or secondary to an
underlying illness.
• Vitrectomy refers to surgical extraction of the
contents of the vitreous chamber and
replacement with a physiologic solution
2/20/2023 9
• The surgeon may also place an intraocular bubble of
either sulphur hexafluoride or perfluropropane to
tamponade the detached surfaces together
– Avoid nitrous oxide if an intraocular gas bubble is used.
– Avoid nitrous oxide in patients who have had an
intraocular bubble placed for several weeks after the
procedure.
– clear instructions in this regard for future anaesthetics.
2/20/2023 10
3. Enucleation and evisceration
• Enucleation is the removal of the whole eye.
– surgical treatment of a retinoblastoma, significant eye
trauma or for cosmetic reasons where an eye is blind.
• It involves the dissection of EOM of the globe.
• similar risk here for the oculocardiac reflex,
although less risk of PONV?.
• Evisceration involves the removal of the contents
of the globe, but retention of the sclera?*
2/20/2023 11
4. Glaucoma
• The causes of glaucoma are varied.
– Primary Congenital glaucoma is caused by a failure
of the development of the trabecular network
– Secondary Glaucoma is usually caused by a
blockage of existing drainage channels
• Treatment may be medical or surgical.
– Medical treatment consists of drugs used to
reduce IOP such as acetazolamide 15 – 30
mg/kg/day which suppresses aqueous production
2/20/2023 12
• After EUA and measurement of IOP, surgical
treatments may vary.
– Trabeculectomy, Iridectomy, Goniotomy and tube
shunt procedures.
• It takes approximately 30 to 60 minutes to
perform a glaucoma procedure.
2/20/2023 13
5. Strabismus surgery
• It is ocular misalignment or deviation of one eye
relative to the visual axis of the other.
• Most strabismus is caused by refractive errors or
muscle imbalance, rare causes include
retinoblastoma or other serious ocular defects and
neurologic disease.
• The surgical correction of strabismus is a
repositioning of the EOMs.
– To strengthen a muscle, a resection is performed and To
weaken a muscle, a recession is performed.
2/20/2023 14
• In severe cases, a resection may be performed
on one muscle and a recession on the
opposing muscle.
• Because visual maturation occurs by age 5
years, strabismus correction usually is
attempted early in childhood.
• It takes 15 to 30 minutes to repair one muscle
• Strabismus repair causes the highest incidence
of oculocardiac reflex?
2/20/2023 15
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Atropine
• Used to produce mydriasis and cyclopiegia.
• The 1% solution contains 0.2 to 0.5 mg of
atropine per drop.
• Systemic reactions, include tachycardia,
flushing, thirst, dry skin, and agitation.
• Atropine is contraindicated in closed-angle
glaucoma?.
2/20/2023 16
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Scopolamine
• One drop of the 0.5% solution has 0.2 mg of
scopolamine.
• CNS excitement can be treated with
physostigmine 0.015 mg/kg IV, repeated one or
two times in a 15- minute period.
• It is contraindicated in closed-angle glaucoma.
2/20/2023 17
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Phenylephrine
• Phenylephrine is used to produce capillary decongestion
and pupillary dilatation.
• Applied to the cornea, it can cause palpitations,
nervousness, tachycardia, headache, nausea and
vomiting, severe hypertension?, reflex bradycardia, and
subarachnoid hemorrhage.
• Solutions of 2.5%, 5%, and 10% (6.25 mg phenylephrine
per drop) are available.
2/20/2023 18
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Epinephrine
• Topical 2% epinephrine will decrease aqueoua secretion,
improve outflow, and lower IOP in open-angle
glaucoma.
• Side-effects include hypertension, palpitations, fainting,
pallor, and tachycardia.
• The effects last about 15 minutes.
• One drop of 2% solution contains 0.5 to 1 mg of
epinephrine.
2/20/2023 19
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Timolol Maleate
• is a beta-blocker used in the treatment of
chronic glaucoma.
• Side- effects include light-headedness, fatigue,
disorientation, depressed CNS function, and
exacerbation of asthma/ bronchospasm,
• increased SVR?, bradycardia, decreased FEV,
and potentiation of systemic beta-blockers can
occur.
2/20/2023 20
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Acetylcholine
• Acetylcholine can be injected intraoperatively
into the anterior chamber to produce miosis.
Side-effects are due to its parasympathetic
action they include hypotension, bradycardia,
and bronchospasm.
2/20/2023 21
SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS
Echothiophate Iodide
• A cholinesterase inhibitor, used as a miotic
agent.
• prolong the effect of both succinyicholine and
ester-type local anesthetics?.
• Levels of pseudocholinesterase decrease by
80% after 2 weeks on the drug.
• Succinyicholine and ester-type local
anesthetics should be avoided.
2/20/2023 22
Acetazolamide
• Causes carbonic anhydrase inhibition and interferes
with the formation of aqueous humor and lowers IOP.
• Metabolic acidosis, dehydration, electrolyte,
abnormalities long term therapy may result in
dyspepsia, allergies.
Mannitol
• Catheterizing
• increase in circulating blood volume w/c can cause
CHF /poor ventricular function/, pulmonary edema,
hypo/hypertension, myocardiac ischemia, renal failure
2/20/2023 23
•
2/20/2023 24
Effects of commonly used anesthetic
agents and techniques on the eyes/IOP
Why we concerned more on IOP?
• It interfere with choroidal and retinal blood
supply & corneal metabolism, potentially causing
– retinal ischemia and corneal opacification.
– choroidal hemorrhage, intraocular bleeding, and
expulsion of intraocular contents.
• Largely dec., increase the risk of retinal
detachment, vitreous hemorrhage, and corneal
edema.
2/20/2023 25
Effect of cardiac and respiratory variables on
IOP
2/20/2023 26
Any anaesthetic event that alters these
parameters can affect intraocular pressure
• laryngoscopy
• Intubation
• Coughing/straining/vomiting 30-40mmHg
• airway obstruction
– Hypoxia /Hypercapnia
• Trendelenburg position
• Face mask ventilation
– Normal blink increase the IOP
– Force full squeeze can increase more
• Drugs
2/20/2023 27
Intravenous Anesthetics
IVA drugs decrease intraocular pressure
Exception is ketamine, which usually raises ABP
and does not relax EOM.
 Current study shows no significant increase in IOP at
usual dose rather, it may cause nystagmus and
blepharospasm which limit its use in eye surgery
Narcotic has little effect
• Atropine usual dose don’t cause a significant
increase in IOP even with open angle glaucoma?
2/20/2023 28
Inhaled anesthetics
• IAA dec. IOP in proportion the depth anaesthesia.
30% -40%
• This decrease has multiple causes:
– drop in blood pressure reduces choroidal volume
– relaxation of the EOM lowers wall tension
– pupillary constriction facilitates aqueous outflow
Nitrous oxide? Should not be used
for patients who had an intravitreal injection of sulfur
hexafluoride (SF6) within the last 30 days or
octafluoropropane (C3F8) within the last 90 days?
2/20/2023 29
Muscle relaxants
• Sux increases IOP by 5-10 mm Hg?
– principally through prolonged contracture of the
EOM (Choroidal vascular dilation, relaxation of orbital
smooth muscles)?
• NDMR minimal effect IOP.
• NDMR has 2 effect:-
– direct effect lower IOP by relaxing Extraocular
muscles;
– indirectly paralysis of respiratory muscle causes
alveolar hypoventilation which increase IOP.
2/20/2023 30
2/20/2023 31
Strategies to prevent increases in IOP
• Avoid direct pressure on the globe
– Patch eye with fox shield
– no retro bulbar or peribular injection
• Avoid increase in CVP
– Prevent coughing and straining during induction and
intubation, extubation
– Avoid head down/Position head up tilt 15 -20%
• Adequate premedication- avoided heavy sedation with?
– IV lidocaine or esmolol to obtund sympathetic reflex
• Avoid pharmacological agent that increase IOP
– Sux/Ketamine?
2/20/2023 32
Preoperative Evaluation
• Establishment of rapport and communication among
the anesthetist, the surgeon, and the patient
• Explanation of potential complications, balanced with
information concerning probability or frequency of
permanent adverse sequelae
• Such an approach also fulfills the medicolegal
responsibilities of the physician to obtain informed
consent.
• Instructions regarding fasting
2/20/2023 33
History
• Thorough Hx and PE are the foundation of safe
patient care
• A complete list of medications
– Anesthetist should be aware of potential systemic effects
of chronically administered eye drops or oral medications
• History of any allergies to medicines, foods, or tape
should be documented
• Previous Hx hospitalization and surgical procedures
and history of adverse reactions to anesthesia is
mandatory
2/20/2023 34
• The Patients might be very young or very old and have
comorbidity
• Infants often present with apnea of prematurity,
bronchopulmonary dysplasia, and PDA or congenital
• Elderly adults are likely to present with CAD, valvular
heart disease, HTN?, cerebrovascular disease, COPD,
diabetes, dementia, Parkinson's disease, renal disease,
arthritis, osteoporosis, or cancer
2/20/2023 35
• Patient factors that could influence anesthetic
management includes dementia, deafness,
language barrior, restlessness leg syndrome,
OSA, tremors, dizziness, and claustrophobia
• particular attention should be paid to
positioning issues such as severe scoliosis or
orthopnea
• check for signs of major cardiac or pulmonary
decompensation
2/20/2023 36
PULMONARY CONSIDERATIONS
• Standard airway assessment is always performed
• Preoperative risk reduction strategies include
cessation smoking, treatment of airflow obstruction
with bronchodilators or steroids, and administration
of antibiotics for respiratory infections.
• Patients should be assessed for sleep apnea
Intravenous sedation is often contraindicate in these
patients.
2/20/2023 37
• Severe hyperglycemia and hypoglycemia
should be avoided, FBS should be checked
preoperatively.
• The potential for autonomic neuropathy
needs to be considered, especially when
elevating the patient from the supine position.
2/20/2023 38
ANTICOAGULANTS
• Many elderly patients are on antiplatelet or
anticoagulant therapy because of CAD or
vascular disease
• Are at higher risk for perioperative hemorrhagic
events, including retrobulbar hemorrhage,
circumorbital hematoma, intravitreous bleeding,
and hyphema.
• The dilemma whether to continue or suspend
antithrombotic therapy prior to surgery?.
2/20/2023 39
• Perioperative management, risks of thrombotic
vs hemorrhagic complications.
• The risk of peirop hemorrhagic complication
depend on:
– The degree of anticoagulation.
– The hemorrhagic potential of the surgical procedure
serious hemorrhagic complication as in orbital and
oculoplastic surgery; of intermediate probability in
vitreoretinal, glaucoma, and corneal transplant
surgery; and least likely in cataract surgery
2/20/2023 40
• Another area of potential concern CAD patients
with drug-eluting stents
• Delaying elective surgery for at least 4 to 6 weeks
after placement of a bare metal stent and for 6-
12 months after drug-eluting stent placement
• Regional anesthesia for eye surgery also presents
another bleeding risk.
• Traditionally, some physicians held that patients
taking antithrombotic medications should not
receive a regional eye block owing to increased
2/20/2023 41
Preoperative testing
• Depending on the medical history and physical
status of the patient, as well as the nature of the
surgical procedure
• routine laboratory tests and ECG have not been
demonstrated to improve outcome
– New chest pain, decreased exercise tolerance,
palpitations, near-syncope, fatigue, or dyspnea, or
irregular pulse on examination.
2/20/2023 42
• Serum electrolytes:- History of severe vomiting or
diarrhea, poor oral intake, changes in diuretic
management, or arrhythmia.
• Urea nitrogen:- Signs or symptoms of renal
problem.
• Serum glucose:- Polydipsia, polyuria, or weight loss.
• Hematocrit/hemoglobin:- Hx of bleeding, poor oral
intake, fatigue, decreased exercise tolerance, or
tachycardia.
2/20/2023 43
Anesthesia for elective eye surgery
• Most elective eye surgery is performed with a
topical or regional anesthetic technique,
combined with monitored anesthesia care (MAC).
– Nature and duration of procedure
– Coagulation status
– Patient’s choice
– Ability to communicate and cooperate
– All of these factors must be considered when
selecting premedication
2/20/2023 44
Requirements for Ophthalmic Surgery
 Akinesia
 Profound analgesia
 Minimal bleeding
 Prevent/manage of oculo-cardiac reflex
 Control of IOP
 Awareness of drug interactions
 Emergence without coughing, straining or vomiting
2/20/2023 45
GENERAL ANESTHESIA
PREMEDICATION
• Pediatric patients often have associated congenital
disorders.
• Adult patients are usually elderly (HTN, DM, CAD).
• Special precautions should be taken to avoid
coughing, bucking, and/or PONV, i.e. deep
anesthesia, complete paralysis, IV lidocaine
2/20/2023 46
GENERAL ANESTHESIA
INDUCTION
The choice of induction technique for eye surgery
usually depends more on
– the patient’s medical problems
– the patient’s eye disease
– the type of surgery contemplated.
• Propofol/thiopenton
• NDMR vs Suxamethonium
• Consider using a reinforced or preformed right-
angle endotracheal tube
2/20/2023 47
MONITORING & MAINTENANCE
• Maintenance with IAA or TIVA
• shared airway, making pulse oximetry mandatory for
all ophthalmologic procedures.
• End-tidal CO2
• Body TM for paediatrics
• Continuous monitoring for breathing-circuit
disconnections or unintentional extubation.
• increases the importance of ECG
• Risk of hypotensive intraop is high? volume
resuscitation + ephedrine should be anticipated
2/20/2023 48
GENERAL ANESTHESIA
EXTUBATION & EMERGENCE
• a smooth emergence from general anesthesia
• deep level of anesthesia
• intravenous lidocaine (1.5 mg/kg)
• extubate early to avoid coughing and bucking
on the ETT
• Anti emetic for PONV
• Analgesia
2/20/2023 49
Anesthesia for emergency eye surgery
• True emergencies such as ocular burns and central
retinal artery occlusion require immediate intervention
• Urgent situations include open globe injuries,
endophthalmitis, acute narrow-angle glaucoma, acute
retinal detachment, corneal foreign body, and lid
laceration.
• Semi urgent conditions include ocular tumors, blowout
fractures of the orbit, congenital cataract, and chronic
retinal detachment.
2/20/2023 50
PREOPERATIVE ASSESSMENT
• Anesthetic concerns
– The mechanism of eye trauma and possibility of
associated traumatic injuries (e.g, orbital or
maxillofacial trauma, skull fractures, subdural
hematoma, intracranial trauma, cervical spine
trauma),
– risk extrusion of ocular contents if IOP becomes
elevated, and
– risk of pulmonary aspiration if the stomach is full
2/20/2023 51
• Findings of the eye exam performed by the
ophthalmologist, including the size of any
ocular perforation.
• Larger defects have a greater chance of extrusion of
ocular contents
• Standard issues for a preanesthetic
consultation(PE evaluation of airway anatomy,
last oral intake of fluids and/or solids.
2/20/2023 52
CHOICE OF ANESTHETIC TECHNIQUE
• Anesthetic goals during emergent eye surgery are
to provide profound analgesia and to prevent
coughing, retching, vomiting, forceful blinking, or
crying
• GA is the most common anesthetic technique for
surgical procedures to treat eye trauma,
especially for open globe injuries.
• In pediatric patients, general anesthesia is almost
always preferred because crying and struggling
2/20/2023 53
2/20/2023 54
2/20/2023 55
Maintenance:-
• A deep plane of anesthesia is maintained during
ophthalmologic surgery so that movement and
coughing are prevented.
• A primary inhalation technique or TIVA
• It is important to prevent coughing, retching, and
vomiting during and after extubation
• Prophylactic antiemetic agents (eg, ondansetron 4
mg and dexamethasone 4 mg
• Administration of IV lidocaine 1 to 2 mg/kg before
extubation
2/20/2023 56
Specific considerations for intraocular surgery
• Position the head at the top edge of the table to
avoid surgical back and neck pain due to poor
posture
• Support the head on a comfortable headrest to
prevent head movement.
• Position the head above or at the level of the
heart
• Restrain arms to the patient's side with the draw
sheet or secure straps on the arm boards to
prevent sudden arm movement.
2/20/2023 57
What OCR?
• Caused by traction on the EOM,
– ocular manipulation
– manual pressure on the globe
– Pinching of conjunctiva
• OCR is seen during eye muscle surgery, detached
retina repair, enucleation and etc
• Manifested by bradycardia, ectopic, nodal rhythm,
AV block, cardiac arrest
• Risk factor pre op anxiety, squint surgery, acidosis,
hypoxia, hypercarbia, increased vagal owing to
age, light anesthesia
2/20/2023 58
2/20/2023 59
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2/20/2023 61
2/20/2023 62
2/20/2023 63
Regional Anesthesia for Ophthalmic
Surgery
• Options for local anesthesia for eye surgery
include:-
 Topical application of local anesthetic
 Placement of a retrobulbar, peribulbar
Sub-Tenon (episcleral) block
• Each of these techniques is commonly combined
with intravenous sedation.
2/20/2023 64
• Local anesthesia is preferred to general anesthesia for
eye surgery.
• Because local anesthesia involves less physiological
trespass.
• Less likely to be associated with postoperative nausea
and vomiting.
• The patient can return to ambulation faster.
• Most patients meet recovery discharge criteria at the
end of surgery.
•
2/20/2023 65
• Eye block procedures have potential complications and
may not provide adequate ophthalmic akinesia or analgesia.
• The appropriate equipment and qualified personnel
required to treat the complications of local anesthesia.
• And induce general anesthesia must be readily available.
2/20/2023 66
FACIAL NERVE BLOCKS
• A facial nerve block is performed when complete
akinesia of the eyelids is desired.
• Three methods for the eyelid block are as follows:
1. Modified van Lint block:
• The needle is placed 1cm lateral to the orbital rim,
• And 2 to 4mL of anesthetic is injected deep on the
periosteum just lateral to the superolateral and
inferolateral orbital rim.
• The disadvantages of this block include discomfort,
proximity to the eye, and common postoperative
ecchymoses.
2/20/2023 67
2. O’Brien block:
• The mandibular condyle is palpated inferior to the
posterior zygomatic process and anterior to the tragus of
the ear as the patient opens and closes the jaw.
• The needle is inserted perpendicular to the skin
approximately 1cm to the periosteum.
• As the needle is withdrawn, 3mL of anesthetic is injected
2/20/2023 68
3. Nadbath-Rehman block:
• A 12-mm, 25-gauge needle is inserted perpendicular to
the skin between the mastoid process and the posterior
border of the mandible.
• The needle is advanced its full length, and after careful
aspiration, 3 mL of anesthetic is injected as the needle is
withdrawn.
• This blocks the entire trunk of the facial nerve.
2/20/2023 69
• The patient should be told to expect a lower facial droop for
several hours postoperatively.
• The major disadvantage to this block is the proximity of the
injection to important structures, such as the carotid artery
and the glossopharyngeal nerve.
• This block is not recommended because it has been
associated with vocal cord paralysis, laryngospasm,
dysphagia, and respiratory distress.
2/20/2023 70
RETROBULBAR BLOCKADE
• Local anesthetic is injected behind the eye into the
cone formed by the extraocular muscles.
• A facial nerve block is utilized to prevent blinking.
• A blunt-tipped 25-gauge needle penetrates the lower
lid at the junction of the middle and lateral one-third
of the orbit.
• Awake patients are instructed to stare supranasally as
the needle is advanced toward the apex of the muscle
cone.
2/20/2023 71
• Commonly, patients undergoing such eye blocks will
receive a brief period of deep sedation or general
anesthesia during the block.
• After aspiration of the syringe to preclude intravascular
injection.
• Then 2 to 5 mL of local anesthetic is injected, and the
needle is removed.
• Lidocaine 2% or bupivacaine (or ropivacaine) 0.75%
are common.
2/20/2023 72
• The addition of epinephrine may reduce bleeding and prolong the
anesthesia.
• A successful retrobulbar block is accompanied by anesthesia, akines
and abolishment of the oculocephalic reflex.
• Complications of retrobulbar injection of local anesthetics include
retrobulbar
hemorrhage
perforation of the globe
optic nerve injury
intravascular injection with resultant convulsions
 oculocardiac reflex
 trigeminal nerve block, respiratory arrest
rarely, acute neurogenic pulmonary edema.
2/20/2023 73
• Forceful injection of local anesthetic into the ophthalmic
artery causes retrograde flow toward the brain and may result
in an instantaneous seizure.
• The postretrobulbar block apnea syndrome is probably due to
injection of local anesthetic into the optic nerve sheath, with
spread into the cerebrospinal fluid.
• In this situation, the central nervous system is exposed to
high concentrations of local anesthetic.
• Leading to mental status changes that may include
unconsciousness.
2/20/2023 74
• Apnea occurs within 20 min and resolves within an hour.
• Treatment is supportive, with positive-pressure ventilation
to prevent hypoxia, bradycardia, and cardiac arrest.
• Adequacy of ventilation must be constantly monitored in
patients who have received retrobulbar anesthesia.
• The adjuvant hyaluronidase is frequently added to local
anesthetic solutions used in eye blocks.
• To enhance the spread and density of the block.
2/20/2023 75
• Patients may rarely experience an allergic reaction to
hyaluronidase.
• Retrobulbar hemorrhage, cellulitis, occult injury, and contact
allergy to topical eye drops must be ruled out in the
differential diagnosis.
• Retrobulbar injection is usually not performed in patients
with bleeding disorders or receiving anticoagulation therapy
2/20/2023 76
• Because of the risk of retrobulbar
hemorrhage, extreme myopia.
• Because the elongated globe increases the
risk of perforation, or an open eye injury.
• Because the pressure from injecting fluid
behind the eye may cause extrusion of
intraocular contents through the wound.
2/20/2023 77
PERIBULBAR BLOCKADE
• The needle does not penetrate the cone
formed by the extraocular muscles.
• Advantages of the peribulbar technique
include less risk of penetration of the
globe, optic nerve, and artery and less
pain on injection.
• Disadvantages include a slower onset and
an increased likelihood of ecchymosis.
2/20/2023 78
• Both techniques will have equal success at
producing akinesia of the eye.
• The peribulbar block is performed with the
patient supine and looking directly ahead.
• After topical anesthesia of the conjunctiva,
one or two transconjunctival injections are
administered.
2/20/2023 79
• As the eyelid is retracted, an inferotemporal
injection is given halfway between the lateral
canthus and the lateral limbus.
• The needle is advanced under the globe,
parallel to the orbital floor; when it passes
the equator of the eye, it is directed slightly
medial (20°) and cephalad (10°), and 5 mL
of local anesthetic is injected.
2/20/2023 80
• Anatomic landmarks for the introduction of a needle or catheter in
most frequently employed eye blocks: (1) medial canthus peribulbar
anesthesia, (2) lacrimal caruncle, (3) semilunaris fold of the
conjunctiva, (4) medial canthus episcleral anesthesia, and (5) inferior
and temporal peribulbar anesthesia.
2/20/2023 81
Sub-Tenon (Episcleral) Block
• Tenon’s fascia surrounds the globe and
extraocular muscles.
• Local anesthetic injected beneath it into the
episcleral space spreads circularly around the
sclera and to the extraocular muscle sheaths.
• A special blunt curved cannula is used for a sub-
Tenon block.
2/20/2023 82
• After topical anesthesia, the conjunctiva is lifted along with Tenon’s
fascia in the inferonasal quadrant with forceps.
• A small nick is then made with blunt-tipped scissors.
• Then slid underneath to create a path in Tenon’s fascia that follows
the contour of the globe and extends past the equator.
• While the eye is still fixed with forceps, the cannula is inserted,
and 3 to 4 mL of local anesthetic is injected.
2/20/2023 83
• Complications with sub-Tenon blocks are significantly less
than with retrobulbar and peribulbar techniques.
• Globe perforation, hemorrhage, cellulitis, permanent visual
loss, and local anesthetic spread into cerebrospinal fluid have
been reported.
2/20/2023 84
TOPICAL ANESTHESIA OF THE EYE
• Use simple topical local anesthetic techniques for anterior
chamber (eg, cataract) and glaucoma operations rather than
local anesthetic injections.
• A typical regimen for topical local anesthesia involves the
application of 0.5% proparacaine local anesthetic drops
• Repeated at 5-min intervals for five applications,
• Followed by the topical application of a local anesthetic gel
(lidocaine plus 2% methyl-cellulose) with a cotton swab to the
inferior and superior conjunctival sacs.
2/20/2023 85
• Ophthalmic 0.5% tetracaine may also be utilized.
• Topical anesthesia is not appropriate for posterior chamber
surgery eg, retinal detachment repair with a buckle.
• It works best for faster surgeons using a gentle surgical
technique that does not require akinesia of the eye.
2/20/2023 86
SEDATION TECHNIQUE/MAC
• Deep sedation is almost never used intraoperatively
because of the risks of apnea, aspiration, and unintentional
patient movement during surgery.
• Though sometimes used during placement of ophthalmic
nerve blocks.
• An intraoperative light sedation regimen that includes small
doses of midazolam, with or without fentanyl or sufentanil,
is recommended.
2/20/2023 87
• Doses vary considerably among patients but should be
administered in small increments.
• Patients may find the administration of eye blocks
frightening and uncomfortable.
• Many anesthesia providers will administer small,
incremental doses of propofol to produce a brief state of
unconsciousness during the regional block.
2/20/2023 88
• Some will substitute a bolus of opioid to produce a brief period of
intense analgesia during the eye block procedure.
• Remifentanil 0.1–0.5 mcg/kg or alfentanil 375–500 mcg.
• Administration of an antiemetic should be considered if an opioid
is used.
• Regardless of the anesthetic technique, American Society of
Anesthesiologists standards for basic monitoring must be
employed.
• And equipment and drugs necessary for airway management and
resuscitation must be immediately available.
2/20/2023 89
What Is MAC Anesthesia?
• MAC anesthesia — also called monitored anesthesia
care or MAC, is a type of anesthesia service during
which a patient is typically still aware, but very
relaxed.
• The amount of sedation provided during MAC is
determined by the anesthesia professional providing
the care.
2/20/2023 90
• A patient may be only lightly sedated, moderately
sedated, or deeply sedated to the point that they’re
completely unaware of the procedure.
• The patient may not even remember any events during
the procedure.
• The level of sedation administered depends on the
health of the patient and the type of surgical or
diagnostic procedure being done.
2/20/2023 91
• This type of anesthesia is typically used for outpatient
procedures where the patient will be going home once
the anesthesia wears off.
• Medications used during MAC include:
midazolam
fentanyl
propofol
2/20/2023 92
• Monitored anesthesia care is the first choice in 10 to 30% of all
surgical procedures.
• It’s typically used for quick surgical procedures.
• MAC is called monitored anesthesia care because a patient’s vitals are
constantly monitored to assess pain control and vital functions.
• Surgical procedures that use MAC include:
 endoscopy
 dental procedures
 bronchoscopy
 eye surgery
 otolaryngologic surgery
 cardiovascular surgery
 neurosurgery
 pain management procedures
2/20/2023 93
MAC anesthesia side effects
• Side effects for monitored anesthesia care are usually
minimum.
• There are cases where one can be allergic to anesthesia,
but the anesthesiologist will work to monitor your reaction
upon administration.
• Common side effects include:
drowsiness
nausea
vomiting
trouble waking from sedation
cardiorespiratory depression
2/20/2023 94
REFERENCES
 Miller’s Anesthesia 9th edition volume 2
 Morgan & Mikhail’s Clinical Anesthesiology 6th Edition
 Alvaro A Macias, M., et al. (Mar 23, 2021.). "Anesthesia
for emergency eye surgery." www.uptodate.com.
 WFSA. Anesthesia Tutorial of The Week 197 20th
September 2010. e-safe
 Jatin D. Mary C. Continuing Education in Anesthesia,
Critical Care & Pain | Volume 7 Number 5 2007. e-safe
 Paul Barash 8th edition
2/20/2023 95

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anesthesiaforophthalmicsurgeryandcomplication-230220112141-c30d0754.pdf

  • 1. Anesthesia for ophthalmic surgery and complication Prepared by:- Gammachis Akuma (Anesthetist) February, 2023 2/20/2023 1
  • 2. Outline • Specific ophthalmic conditions and procedures • Effects of commonly used anesthetic agents and techniques on the eyes • Preoperative assessment of ophthalmic patients • Anesthesia for elective vs emergency (traumatic) ophthalmic surgery • General anesthesia • Sedation techniques/MAC • Regional anesthesia (preparation of LA, blocks, infiltration, topical and complication) 2/20/2023 2
  • 3. Objective • At the end of this lesson participants will be able:- – To identify effect of anesthetic agent on IOP – To describe systemic effect of commonly used ophthalmic drugs – To perform regional block for ophthalmic surgery – To identify indications for providing regional anesthesia for patients undergoing eye surgery. – To describe complications that may result from regional anesthesia for eye blocks. 2/20/2023 3
  • 4. SPECIFIC OPHTHALMIC CONDITIONS AND PROCEDURES 2/20/2023 4
  • 6. 1. Cataract extraction • Cataracts are opacities of the crystalline lens of the eye. • Cataract surgery incurs little risk since physiologic stress is minimal and no blood loss or fluid shifts occur • No benefits derive from routine testing before cataract surgery 2/20/2023 6
  • 7. Cataract cont… • Etiology may be varied – Hereditary cataracts. – Syndromes may be associated with cataracts. – Metabolic causes – Blunt or penetrating trauma – Inflammation – Tumors, such as retinoblastoma. – Intrauterine infection – Radiation for leukemia might cause cataracts. – Chronic steroid use 2/20/2023 7
  • 8. Cataract cont.. • Treatment involves surgical implantation of an intraocular lens, which may need to be done very early • The procedure takes about 30 - 60 minutes, but complications can be more frequent in children, • depending on the density of the cataract, the patient’s cooperation, and the skill and experience of surgeons. 2/20/2023 8
  • 9. 2. Vitreoretinal surgery • Vitreoretinal surgery is performed for the repair of a detached retina – related to a defect in the retina, or secondary to an underlying illness. • Vitrectomy refers to surgical extraction of the contents of the vitreous chamber and replacement with a physiologic solution 2/20/2023 9
  • 10. • The surgeon may also place an intraocular bubble of either sulphur hexafluoride or perfluropropane to tamponade the detached surfaces together – Avoid nitrous oxide if an intraocular gas bubble is used. – Avoid nitrous oxide in patients who have had an intraocular bubble placed for several weeks after the procedure. – clear instructions in this regard for future anaesthetics. 2/20/2023 10
  • 11. 3. Enucleation and evisceration • Enucleation is the removal of the whole eye. – surgical treatment of a retinoblastoma, significant eye trauma or for cosmetic reasons where an eye is blind. • It involves the dissection of EOM of the globe. • similar risk here for the oculocardiac reflex, although less risk of PONV?. • Evisceration involves the removal of the contents of the globe, but retention of the sclera?* 2/20/2023 11
  • 12. 4. Glaucoma • The causes of glaucoma are varied. – Primary Congenital glaucoma is caused by a failure of the development of the trabecular network – Secondary Glaucoma is usually caused by a blockage of existing drainage channels • Treatment may be medical or surgical. – Medical treatment consists of drugs used to reduce IOP such as acetazolamide 15 – 30 mg/kg/day which suppresses aqueous production 2/20/2023 12
  • 13. • After EUA and measurement of IOP, surgical treatments may vary. – Trabeculectomy, Iridectomy, Goniotomy and tube shunt procedures. • It takes approximately 30 to 60 minutes to perform a glaucoma procedure. 2/20/2023 13
  • 14. 5. Strabismus surgery • It is ocular misalignment or deviation of one eye relative to the visual axis of the other. • Most strabismus is caused by refractive errors or muscle imbalance, rare causes include retinoblastoma or other serious ocular defects and neurologic disease. • The surgical correction of strabismus is a repositioning of the EOMs. – To strengthen a muscle, a resection is performed and To weaken a muscle, a recession is performed. 2/20/2023 14
  • 15. • In severe cases, a resection may be performed on one muscle and a recession on the opposing muscle. • Because visual maturation occurs by age 5 years, strabismus correction usually is attempted early in childhood. • It takes 15 to 30 minutes to repair one muscle • Strabismus repair causes the highest incidence of oculocardiac reflex? 2/20/2023 15
  • 16. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Atropine • Used to produce mydriasis and cyclopiegia. • The 1% solution contains 0.2 to 0.5 mg of atropine per drop. • Systemic reactions, include tachycardia, flushing, thirst, dry skin, and agitation. • Atropine is contraindicated in closed-angle glaucoma?. 2/20/2023 16
  • 17. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Scopolamine • One drop of the 0.5% solution has 0.2 mg of scopolamine. • CNS excitement can be treated with physostigmine 0.015 mg/kg IV, repeated one or two times in a 15- minute period. • It is contraindicated in closed-angle glaucoma. 2/20/2023 17
  • 18. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Phenylephrine • Phenylephrine is used to produce capillary decongestion and pupillary dilatation. • Applied to the cornea, it can cause palpitations, nervousness, tachycardia, headache, nausea and vomiting, severe hypertension?, reflex bradycardia, and subarachnoid hemorrhage. • Solutions of 2.5%, 5%, and 10% (6.25 mg phenylephrine per drop) are available. 2/20/2023 18
  • 19. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Epinephrine • Topical 2% epinephrine will decrease aqueoua secretion, improve outflow, and lower IOP in open-angle glaucoma. • Side-effects include hypertension, palpitations, fainting, pallor, and tachycardia. • The effects last about 15 minutes. • One drop of 2% solution contains 0.5 to 1 mg of epinephrine. 2/20/2023 19
  • 20. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Timolol Maleate • is a beta-blocker used in the treatment of chronic glaucoma. • Side- effects include light-headedness, fatigue, disorientation, depressed CNS function, and exacerbation of asthma/ bronchospasm, • increased SVR?, bradycardia, decreased FEV, and potentiation of systemic beta-blockers can occur. 2/20/2023 20
  • 21. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Acetylcholine • Acetylcholine can be injected intraoperatively into the anterior chamber to produce miosis. Side-effects are due to its parasympathetic action they include hypotension, bradycardia, and bronchospasm. 2/20/2023 21
  • 22. SYSTEMIC EFFECTS OF OPHTHALMIC DRUGS Echothiophate Iodide • A cholinesterase inhibitor, used as a miotic agent. • prolong the effect of both succinyicholine and ester-type local anesthetics?. • Levels of pseudocholinesterase decrease by 80% after 2 weeks on the drug. • Succinyicholine and ester-type local anesthetics should be avoided. 2/20/2023 22
  • 23. Acetazolamide • Causes carbonic anhydrase inhibition and interferes with the formation of aqueous humor and lowers IOP. • Metabolic acidosis, dehydration, electrolyte, abnormalities long term therapy may result in dyspepsia, allergies. Mannitol • Catheterizing • increase in circulating blood volume w/c can cause CHF /poor ventricular function/, pulmonary edema, hypo/hypertension, myocardiac ischemia, renal failure 2/20/2023 23
  • 25. Effects of commonly used anesthetic agents and techniques on the eyes/IOP Why we concerned more on IOP? • It interfere with choroidal and retinal blood supply & corneal metabolism, potentially causing – retinal ischemia and corneal opacification. – choroidal hemorrhage, intraocular bleeding, and expulsion of intraocular contents. • Largely dec., increase the risk of retinal detachment, vitreous hemorrhage, and corneal edema. 2/20/2023 25
  • 26. Effect of cardiac and respiratory variables on IOP 2/20/2023 26
  • 27. Any anaesthetic event that alters these parameters can affect intraocular pressure • laryngoscopy • Intubation • Coughing/straining/vomiting 30-40mmHg • airway obstruction – Hypoxia /Hypercapnia • Trendelenburg position • Face mask ventilation – Normal blink increase the IOP – Force full squeeze can increase more • Drugs 2/20/2023 27
  • 28. Intravenous Anesthetics IVA drugs decrease intraocular pressure Exception is ketamine, which usually raises ABP and does not relax EOM.  Current study shows no significant increase in IOP at usual dose rather, it may cause nystagmus and blepharospasm which limit its use in eye surgery Narcotic has little effect • Atropine usual dose don’t cause a significant increase in IOP even with open angle glaucoma? 2/20/2023 28
  • 29. Inhaled anesthetics • IAA dec. IOP in proportion the depth anaesthesia. 30% -40% • This decrease has multiple causes: – drop in blood pressure reduces choroidal volume – relaxation of the EOM lowers wall tension – pupillary constriction facilitates aqueous outflow Nitrous oxide? Should not be used for patients who had an intravitreal injection of sulfur hexafluoride (SF6) within the last 30 days or octafluoropropane (C3F8) within the last 90 days? 2/20/2023 29
  • 30. Muscle relaxants • Sux increases IOP by 5-10 mm Hg? – principally through prolonged contracture of the EOM (Choroidal vascular dilation, relaxation of orbital smooth muscles)? • NDMR minimal effect IOP. • NDMR has 2 effect:- – direct effect lower IOP by relaxing Extraocular muscles; – indirectly paralysis of respiratory muscle causes alveolar hypoventilation which increase IOP. 2/20/2023 30
  • 32. Strategies to prevent increases in IOP • Avoid direct pressure on the globe – Patch eye with fox shield – no retro bulbar or peribular injection • Avoid increase in CVP – Prevent coughing and straining during induction and intubation, extubation – Avoid head down/Position head up tilt 15 -20% • Adequate premedication- avoided heavy sedation with? – IV lidocaine or esmolol to obtund sympathetic reflex • Avoid pharmacological agent that increase IOP – Sux/Ketamine? 2/20/2023 32
  • 33. Preoperative Evaluation • Establishment of rapport and communication among the anesthetist, the surgeon, and the patient • Explanation of potential complications, balanced with information concerning probability or frequency of permanent adverse sequelae • Such an approach also fulfills the medicolegal responsibilities of the physician to obtain informed consent. • Instructions regarding fasting 2/20/2023 33
  • 34. History • Thorough Hx and PE are the foundation of safe patient care • A complete list of medications – Anesthetist should be aware of potential systemic effects of chronically administered eye drops or oral medications • History of any allergies to medicines, foods, or tape should be documented • Previous Hx hospitalization and surgical procedures and history of adverse reactions to anesthesia is mandatory 2/20/2023 34
  • 35. • The Patients might be very young or very old and have comorbidity • Infants often present with apnea of prematurity, bronchopulmonary dysplasia, and PDA or congenital • Elderly adults are likely to present with CAD, valvular heart disease, HTN?, cerebrovascular disease, COPD, diabetes, dementia, Parkinson's disease, renal disease, arthritis, osteoporosis, or cancer 2/20/2023 35
  • 36. • Patient factors that could influence anesthetic management includes dementia, deafness, language barrior, restlessness leg syndrome, OSA, tremors, dizziness, and claustrophobia • particular attention should be paid to positioning issues such as severe scoliosis or orthopnea • check for signs of major cardiac or pulmonary decompensation 2/20/2023 36
  • 37. PULMONARY CONSIDERATIONS • Standard airway assessment is always performed • Preoperative risk reduction strategies include cessation smoking, treatment of airflow obstruction with bronchodilators or steroids, and administration of antibiotics for respiratory infections. • Patients should be assessed for sleep apnea Intravenous sedation is often contraindicate in these patients. 2/20/2023 37
  • 38. • Severe hyperglycemia and hypoglycemia should be avoided, FBS should be checked preoperatively. • The potential for autonomic neuropathy needs to be considered, especially when elevating the patient from the supine position. 2/20/2023 38
  • 39. ANTICOAGULANTS • Many elderly patients are on antiplatelet or anticoagulant therapy because of CAD or vascular disease • Are at higher risk for perioperative hemorrhagic events, including retrobulbar hemorrhage, circumorbital hematoma, intravitreous bleeding, and hyphema. • The dilemma whether to continue or suspend antithrombotic therapy prior to surgery?. 2/20/2023 39
  • 40. • Perioperative management, risks of thrombotic vs hemorrhagic complications. • The risk of peirop hemorrhagic complication depend on: – The degree of anticoagulation. – The hemorrhagic potential of the surgical procedure serious hemorrhagic complication as in orbital and oculoplastic surgery; of intermediate probability in vitreoretinal, glaucoma, and corneal transplant surgery; and least likely in cataract surgery 2/20/2023 40
  • 41. • Another area of potential concern CAD patients with drug-eluting stents • Delaying elective surgery for at least 4 to 6 weeks after placement of a bare metal stent and for 6- 12 months after drug-eluting stent placement • Regional anesthesia for eye surgery also presents another bleeding risk. • Traditionally, some physicians held that patients taking antithrombotic medications should not receive a regional eye block owing to increased 2/20/2023 41
  • 42. Preoperative testing • Depending on the medical history and physical status of the patient, as well as the nature of the surgical procedure • routine laboratory tests and ECG have not been demonstrated to improve outcome – New chest pain, decreased exercise tolerance, palpitations, near-syncope, fatigue, or dyspnea, or irregular pulse on examination. 2/20/2023 42
  • 43. • Serum electrolytes:- History of severe vomiting or diarrhea, poor oral intake, changes in diuretic management, or arrhythmia. • Urea nitrogen:- Signs or symptoms of renal problem. • Serum glucose:- Polydipsia, polyuria, or weight loss. • Hematocrit/hemoglobin:- Hx of bleeding, poor oral intake, fatigue, decreased exercise tolerance, or tachycardia. 2/20/2023 43
  • 44. Anesthesia for elective eye surgery • Most elective eye surgery is performed with a topical or regional anesthetic technique, combined with monitored anesthesia care (MAC). – Nature and duration of procedure – Coagulation status – Patient’s choice – Ability to communicate and cooperate – All of these factors must be considered when selecting premedication 2/20/2023 44
  • 45. Requirements for Ophthalmic Surgery  Akinesia  Profound analgesia  Minimal bleeding  Prevent/manage of oculo-cardiac reflex  Control of IOP  Awareness of drug interactions  Emergence without coughing, straining or vomiting 2/20/2023 45
  • 46. GENERAL ANESTHESIA PREMEDICATION • Pediatric patients often have associated congenital disorders. • Adult patients are usually elderly (HTN, DM, CAD). • Special precautions should be taken to avoid coughing, bucking, and/or PONV, i.e. deep anesthesia, complete paralysis, IV lidocaine 2/20/2023 46
  • 47. GENERAL ANESTHESIA INDUCTION The choice of induction technique for eye surgery usually depends more on – the patient’s medical problems – the patient’s eye disease – the type of surgery contemplated. • Propofol/thiopenton • NDMR vs Suxamethonium • Consider using a reinforced or preformed right- angle endotracheal tube 2/20/2023 47
  • 48. MONITORING & MAINTENANCE • Maintenance with IAA or TIVA • shared airway, making pulse oximetry mandatory for all ophthalmologic procedures. • End-tidal CO2 • Body TM for paediatrics • Continuous monitoring for breathing-circuit disconnections or unintentional extubation. • increases the importance of ECG • Risk of hypotensive intraop is high? volume resuscitation + ephedrine should be anticipated 2/20/2023 48
  • 49. GENERAL ANESTHESIA EXTUBATION & EMERGENCE • a smooth emergence from general anesthesia • deep level of anesthesia • intravenous lidocaine (1.5 mg/kg) • extubate early to avoid coughing and bucking on the ETT • Anti emetic for PONV • Analgesia 2/20/2023 49
  • 50. Anesthesia for emergency eye surgery • True emergencies such as ocular burns and central retinal artery occlusion require immediate intervention • Urgent situations include open globe injuries, endophthalmitis, acute narrow-angle glaucoma, acute retinal detachment, corneal foreign body, and lid laceration. • Semi urgent conditions include ocular tumors, blowout fractures of the orbit, congenital cataract, and chronic retinal detachment. 2/20/2023 50
  • 51. PREOPERATIVE ASSESSMENT • Anesthetic concerns – The mechanism of eye trauma and possibility of associated traumatic injuries (e.g, orbital or maxillofacial trauma, skull fractures, subdural hematoma, intracranial trauma, cervical spine trauma), – risk extrusion of ocular contents if IOP becomes elevated, and – risk of pulmonary aspiration if the stomach is full 2/20/2023 51
  • 52. • Findings of the eye exam performed by the ophthalmologist, including the size of any ocular perforation. • Larger defects have a greater chance of extrusion of ocular contents • Standard issues for a preanesthetic consultation(PE evaluation of airway anatomy, last oral intake of fluids and/or solids. 2/20/2023 52
  • 53. CHOICE OF ANESTHETIC TECHNIQUE • Anesthetic goals during emergent eye surgery are to provide profound analgesia and to prevent coughing, retching, vomiting, forceful blinking, or crying • GA is the most common anesthetic technique for surgical procedures to treat eye trauma, especially for open globe injuries. • In pediatric patients, general anesthesia is almost always preferred because crying and struggling 2/20/2023 53
  • 56. Maintenance:- • A deep plane of anesthesia is maintained during ophthalmologic surgery so that movement and coughing are prevented. • A primary inhalation technique or TIVA • It is important to prevent coughing, retching, and vomiting during and after extubation • Prophylactic antiemetic agents (eg, ondansetron 4 mg and dexamethasone 4 mg • Administration of IV lidocaine 1 to 2 mg/kg before extubation 2/20/2023 56
  • 57. Specific considerations for intraocular surgery • Position the head at the top edge of the table to avoid surgical back and neck pain due to poor posture • Support the head on a comfortable headrest to prevent head movement. • Position the head above or at the level of the heart • Restrain arms to the patient's side with the draw sheet or secure straps on the arm boards to prevent sudden arm movement. 2/20/2023 57
  • 58. What OCR? • Caused by traction on the EOM, – ocular manipulation – manual pressure on the globe – Pinching of conjunctiva • OCR is seen during eye muscle surgery, detached retina repair, enucleation and etc • Manifested by bradycardia, ectopic, nodal rhythm, AV block, cardiac arrest • Risk factor pre op anxiety, squint surgery, acidosis, hypoxia, hypercarbia, increased vagal owing to age, light anesthesia 2/20/2023 58
  • 64. Regional Anesthesia for Ophthalmic Surgery • Options for local anesthesia for eye surgery include:-  Topical application of local anesthetic  Placement of a retrobulbar, peribulbar Sub-Tenon (episcleral) block • Each of these techniques is commonly combined with intravenous sedation. 2/20/2023 64
  • 65. • Local anesthesia is preferred to general anesthesia for eye surgery. • Because local anesthesia involves less physiological trespass. • Less likely to be associated with postoperative nausea and vomiting. • The patient can return to ambulation faster. • Most patients meet recovery discharge criteria at the end of surgery. • 2/20/2023 65
  • 66. • Eye block procedures have potential complications and may not provide adequate ophthalmic akinesia or analgesia. • The appropriate equipment and qualified personnel required to treat the complications of local anesthesia. • And induce general anesthesia must be readily available. 2/20/2023 66
  • 67. FACIAL NERVE BLOCKS • A facial nerve block is performed when complete akinesia of the eyelids is desired. • Three methods for the eyelid block are as follows: 1. Modified van Lint block: • The needle is placed 1cm lateral to the orbital rim, • And 2 to 4mL of anesthetic is injected deep on the periosteum just lateral to the superolateral and inferolateral orbital rim. • The disadvantages of this block include discomfort, proximity to the eye, and common postoperative ecchymoses. 2/20/2023 67
  • 68. 2. O’Brien block: • The mandibular condyle is palpated inferior to the posterior zygomatic process and anterior to the tragus of the ear as the patient opens and closes the jaw. • The needle is inserted perpendicular to the skin approximately 1cm to the periosteum. • As the needle is withdrawn, 3mL of anesthetic is injected 2/20/2023 68
  • 69. 3. Nadbath-Rehman block: • A 12-mm, 25-gauge needle is inserted perpendicular to the skin between the mastoid process and the posterior border of the mandible. • The needle is advanced its full length, and after careful aspiration, 3 mL of anesthetic is injected as the needle is withdrawn. • This blocks the entire trunk of the facial nerve. 2/20/2023 69
  • 70. • The patient should be told to expect a lower facial droop for several hours postoperatively. • The major disadvantage to this block is the proximity of the injection to important structures, such as the carotid artery and the glossopharyngeal nerve. • This block is not recommended because it has been associated with vocal cord paralysis, laryngospasm, dysphagia, and respiratory distress. 2/20/2023 70
  • 71. RETROBULBAR BLOCKADE • Local anesthetic is injected behind the eye into the cone formed by the extraocular muscles. • A facial nerve block is utilized to prevent blinking. • A blunt-tipped 25-gauge needle penetrates the lower lid at the junction of the middle and lateral one-third of the orbit. • Awake patients are instructed to stare supranasally as the needle is advanced toward the apex of the muscle cone. 2/20/2023 71
  • 72. • Commonly, patients undergoing such eye blocks will receive a brief period of deep sedation or general anesthesia during the block. • After aspiration of the syringe to preclude intravascular injection. • Then 2 to 5 mL of local anesthetic is injected, and the needle is removed. • Lidocaine 2% or bupivacaine (or ropivacaine) 0.75% are common. 2/20/2023 72
  • 73. • The addition of epinephrine may reduce bleeding and prolong the anesthesia. • A successful retrobulbar block is accompanied by anesthesia, akines and abolishment of the oculocephalic reflex. • Complications of retrobulbar injection of local anesthetics include retrobulbar hemorrhage perforation of the globe optic nerve injury intravascular injection with resultant convulsions  oculocardiac reflex  trigeminal nerve block, respiratory arrest rarely, acute neurogenic pulmonary edema. 2/20/2023 73
  • 74. • Forceful injection of local anesthetic into the ophthalmic artery causes retrograde flow toward the brain and may result in an instantaneous seizure. • The postretrobulbar block apnea syndrome is probably due to injection of local anesthetic into the optic nerve sheath, with spread into the cerebrospinal fluid. • In this situation, the central nervous system is exposed to high concentrations of local anesthetic. • Leading to mental status changes that may include unconsciousness. 2/20/2023 74
  • 75. • Apnea occurs within 20 min and resolves within an hour. • Treatment is supportive, with positive-pressure ventilation to prevent hypoxia, bradycardia, and cardiac arrest. • Adequacy of ventilation must be constantly monitored in patients who have received retrobulbar anesthesia. • The adjuvant hyaluronidase is frequently added to local anesthetic solutions used in eye blocks. • To enhance the spread and density of the block. 2/20/2023 75
  • 76. • Patients may rarely experience an allergic reaction to hyaluronidase. • Retrobulbar hemorrhage, cellulitis, occult injury, and contact allergy to topical eye drops must be ruled out in the differential diagnosis. • Retrobulbar injection is usually not performed in patients with bleeding disorders or receiving anticoagulation therapy 2/20/2023 76
  • 77. • Because of the risk of retrobulbar hemorrhage, extreme myopia. • Because the elongated globe increases the risk of perforation, or an open eye injury. • Because the pressure from injecting fluid behind the eye may cause extrusion of intraocular contents through the wound. 2/20/2023 77
  • 78. PERIBULBAR BLOCKADE • The needle does not penetrate the cone formed by the extraocular muscles. • Advantages of the peribulbar technique include less risk of penetration of the globe, optic nerve, and artery and less pain on injection. • Disadvantages include a slower onset and an increased likelihood of ecchymosis. 2/20/2023 78
  • 79. • Both techniques will have equal success at producing akinesia of the eye. • The peribulbar block is performed with the patient supine and looking directly ahead. • After topical anesthesia of the conjunctiva, one or two transconjunctival injections are administered. 2/20/2023 79
  • 80. • As the eyelid is retracted, an inferotemporal injection is given halfway between the lateral canthus and the lateral limbus. • The needle is advanced under the globe, parallel to the orbital floor; when it passes the equator of the eye, it is directed slightly medial (20°) and cephalad (10°), and 5 mL of local anesthetic is injected. 2/20/2023 80
  • 81. • Anatomic landmarks for the introduction of a needle or catheter in most frequently employed eye blocks: (1) medial canthus peribulbar anesthesia, (2) lacrimal caruncle, (3) semilunaris fold of the conjunctiva, (4) medial canthus episcleral anesthesia, and (5) inferior and temporal peribulbar anesthesia. 2/20/2023 81
  • 82. Sub-Tenon (Episcleral) Block • Tenon’s fascia surrounds the globe and extraocular muscles. • Local anesthetic injected beneath it into the episcleral space spreads circularly around the sclera and to the extraocular muscle sheaths. • A special blunt curved cannula is used for a sub- Tenon block. 2/20/2023 82
  • 83. • After topical anesthesia, the conjunctiva is lifted along with Tenon’s fascia in the inferonasal quadrant with forceps. • A small nick is then made with blunt-tipped scissors. • Then slid underneath to create a path in Tenon’s fascia that follows the contour of the globe and extends past the equator. • While the eye is still fixed with forceps, the cannula is inserted, and 3 to 4 mL of local anesthetic is injected. 2/20/2023 83
  • 84. • Complications with sub-Tenon blocks are significantly less than with retrobulbar and peribulbar techniques. • Globe perforation, hemorrhage, cellulitis, permanent visual loss, and local anesthetic spread into cerebrospinal fluid have been reported. 2/20/2023 84
  • 85. TOPICAL ANESTHESIA OF THE EYE • Use simple topical local anesthetic techniques for anterior chamber (eg, cataract) and glaucoma operations rather than local anesthetic injections. • A typical regimen for topical local anesthesia involves the application of 0.5% proparacaine local anesthetic drops • Repeated at 5-min intervals for five applications, • Followed by the topical application of a local anesthetic gel (lidocaine plus 2% methyl-cellulose) with a cotton swab to the inferior and superior conjunctival sacs. 2/20/2023 85
  • 86. • Ophthalmic 0.5% tetracaine may also be utilized. • Topical anesthesia is not appropriate for posterior chamber surgery eg, retinal detachment repair with a buckle. • It works best for faster surgeons using a gentle surgical technique that does not require akinesia of the eye. 2/20/2023 86
  • 87. SEDATION TECHNIQUE/MAC • Deep sedation is almost never used intraoperatively because of the risks of apnea, aspiration, and unintentional patient movement during surgery. • Though sometimes used during placement of ophthalmic nerve blocks. • An intraoperative light sedation regimen that includes small doses of midazolam, with or without fentanyl or sufentanil, is recommended. 2/20/2023 87
  • 88. • Doses vary considerably among patients but should be administered in small increments. • Patients may find the administration of eye blocks frightening and uncomfortable. • Many anesthesia providers will administer small, incremental doses of propofol to produce a brief state of unconsciousness during the regional block. 2/20/2023 88
  • 89. • Some will substitute a bolus of opioid to produce a brief period of intense analgesia during the eye block procedure. • Remifentanil 0.1–0.5 mcg/kg or alfentanil 375–500 mcg. • Administration of an antiemetic should be considered if an opioid is used. • Regardless of the anesthetic technique, American Society of Anesthesiologists standards for basic monitoring must be employed. • And equipment and drugs necessary for airway management and resuscitation must be immediately available. 2/20/2023 89
  • 90. What Is MAC Anesthesia? • MAC anesthesia — also called monitored anesthesia care or MAC, is a type of anesthesia service during which a patient is typically still aware, but very relaxed. • The amount of sedation provided during MAC is determined by the anesthesia professional providing the care. 2/20/2023 90
  • 91. • A patient may be only lightly sedated, moderately sedated, or deeply sedated to the point that they’re completely unaware of the procedure. • The patient may not even remember any events during the procedure. • The level of sedation administered depends on the health of the patient and the type of surgical or diagnostic procedure being done. 2/20/2023 91
  • 92. • This type of anesthesia is typically used for outpatient procedures where the patient will be going home once the anesthesia wears off. • Medications used during MAC include: midazolam fentanyl propofol 2/20/2023 92
  • 93. • Monitored anesthesia care is the first choice in 10 to 30% of all surgical procedures. • It’s typically used for quick surgical procedures. • MAC is called monitored anesthesia care because a patient’s vitals are constantly monitored to assess pain control and vital functions. • Surgical procedures that use MAC include:  endoscopy  dental procedures  bronchoscopy  eye surgery  otolaryngologic surgery  cardiovascular surgery  neurosurgery  pain management procedures 2/20/2023 93
  • 94. MAC anesthesia side effects • Side effects for monitored anesthesia care are usually minimum. • There are cases where one can be allergic to anesthesia, but the anesthesiologist will work to monitor your reaction upon administration. • Common side effects include: drowsiness nausea vomiting trouble waking from sedation cardiorespiratory depression 2/20/2023 94
  • 95. REFERENCES  Miller’s Anesthesia 9th edition volume 2  Morgan & Mikhail’s Clinical Anesthesiology 6th Edition  Alvaro A Macias, M., et al. (Mar 23, 2021.). "Anesthesia for emergency eye surgery." www.uptodate.com.  WFSA. Anesthesia Tutorial of The Week 197 20th September 2010. e-safe  Jatin D. Mary C. Continuing Education in Anesthesia, Critical Care & Pain | Volume 7 Number 5 2007. e-safe  Paul Barash 8th edition 2/20/2023 95