1. Mistaken Identity
Many have mistakenly brought
their loved ones to get
exorcised believing that the
sudden erratic and sometimes
violent behavior was due to
demonic possession
3. History Behind the Disease
Autoimmune encephalitis hasn’t always been recognized for what it is, but now it’s becoming better
understood as a cause of cognitive degeneration and psychological disarray. Half the cases
have gone undetected, even though it is well understood as a distinct entity.
This is because detection of the disease can be through symptoms that are related to many, much
more prevalent illnesses. Though treatment can be effective, it is a ticking time bomb for
treatment of the wrong diagnosis, potentially triggering escalation of symptoms.
4. Symptoms and Diagnosis
Detection of antibodies in deep grey matter neurons such as the N-methyl-D-asparate (NMDA) receptors or voltage-
gated potassium channels (VGKC) has been observed.
These auto-antibodies (NMDA,VGKC) can be found through serum lab tests, and magnetic resonance imaging can
show inflammation, and spinal tap can reveal auto-antibodies and other biomarkers in the cerebrospinal fluid that
point to autoimmune encephalitis.
5. The Terror-toma “Teratoma”
An undeveloped Oocyte that grows out of stem cells
and hormones
Afflicts 50% of Women with NMDA-type encephalitis
6.
7. Treatment and Prognoses
Immunomodulating therapies like intravenous
immunoglobulin (IVIG), glucocorticosteroids, plasma
exchange and drugs like cyclophosphamide, rituximab,
mycophenolate mofetil, azathioprine, in combination or
individually, have all produced good results and are
readily available.
Current research in Anti-NMDA encephalitis reveals that
25% of patients suffer from severe deficits or death.
There is a 12% relapse risk in 2 years. Early treatment is
one of the most important predictors of a good
outcome.
8. Resources and Support
Autoimmune Encephalitis Alliance- www.aealliance.org
AE Clinicians Network: http://wp.me/p41oPS-lu
The Encephalitis Society- www.encephalitis.info
Books: Brain on Fire: My Month of Madness Susannah
Cahalan
http://www.ctvnews.ca/parents-warn-of-mystery-illness-
misdiagnosed-in-kids-1.701777
