Anger is a normal human emotion, but hostility and aggression are inappropriate expressions of anger. Hostility is expressed through verbal abuse, lack of cooperation, violating rules, or threatening behavior. Aggression can stem from neurobiological or psychosocial factors like low serotonin, damage to the limbic system, or a failure to develop impulse control. Common nursing diagnoses related to hostility and aggression include risk for other-directed violence and ineffective coping. Nurses intervene early in the cycle of aggression through managing the environment, deescalating aggressive behavior, using restraints or seclusion if needed for safety, and helping the client recover and process what happened after a crisis.