FNAC involves aspirating cells using fine needles from lesions to determine if they are benign or malignant. It requires clinical skills like anatomy knowledge and physical exam proficiency. Cytology examines cell patterns in smears while histology looks at tissue. Pathologists are best for conducting FNAC as they examine patients and interpret results. Nurses play an important role by educating patients, obtaining consent, monitoring patients during the procedure, and ensuring follow-up care. FNAC is fast, accurate, and low-risk, frequently providing a diagnosis to guide treatment.