The document summarizes the science goals and capabilities of the James Webb Space Telescope (JWST). It discusses how JWST will study the first stars and galaxies, characterize exoplanets, and investigate topics like dark energy. Key areas of research include observing the early universe to map the first luminous sources and determine reionization; detecting the first supernovae; studying star and planet formation; measuring dark energy through observations of distant supernovae; and directly imaging exoplanets and analyzing their atmospheres. The document outlines the telescope's role in addressing major questions across astronomy and its potential for transformative discoveries.