15. • Mom with no
prenatal care
delivers
undiagnosed
twins at EGA
34 weeks
16.
17.
18.
19. Diagnosis to confirm iud
history &examination
-Absence of fetal movements
-Retrogression of the positive breast changes.
- Gradual retrogression of the height of the uterus
- Uterine tone is diminished
- Fetal movement are not felt during palpation.
- Fetal heart sound are not audible
20. Diagnosis (contd…)
-Straight- X-ray abdomen
- Spalding sign: it usually appears 7 days after
I.U.F.D.
- Hyperflexion of the spine
- Crowding of the ribs shadow
- (Robert’s sign) Appearance of gas shadow in great
vessels : 12 hours
22. Evaluation of iufd to detect the cause
• I-Maternal medical conditions
• VTE/ PE
• DM
• HPT
• Thrombophilia
• SLE
• Autoimmune disease
• Severe Anemia
• Epilepsy
• Heart disease
II-Past OB Hx
•Gestational HTN with adverse sequele
•Placental abruption
•IUFD
•Recurrent abortions
•Baby with congenital anomaly / hereditary
condition
•IUGR
23. Current Pregnancy Hx
• Maternal age
• Gestational age at fetal death
• HPT
• DM/ Gestational D
• Smoking , alcohol, or drug abuse
• Abdominal trauma
• Choliestasis
• Placental abruption
• PROM or prelabour ROM
32. 3. INVESTIGATIONS
• Maternal investigations:
• CBC
• Blood Group & antibody screen
• HB A1 C
• Kleihauer Baket test
• Serological screening for Rubella CMV,
Toxoplasmosis, Syphilis, Herpes & Parvovirus
• Karyotyping of both parents
• Hb electrophoresis'
• Antiplatelet antibodies
• Thrombophilia screening (ant thrombin iii, Protein C &
S deficiency , factor IV leiden,Factor II mutation, lupus
anticoagulant, anticardolipin antibodies)
• DIC
33. cont
• Fetal investigations
• Fetal autopsy
• Karyotype
• (specimen taken from cord blood, intracardiac
blood, body fluids, skin, spleen,
Placental wedge, or amniotic Fluid)
• Fetography
• Radiography
34. cont
• Placental investigations
• Chorionicity of placenta in twins
• Cord thrombosis or knots
• Infarcts, thrombosis, abruption,
• Vascular malformations
• Signs of infection
• Bacterial culture for E coli,
• Listeria, group B strept.
36. Management
• Explain the problem to the woman and her family.
Discuss with them the options of expectant or active
management.
• If expectant management is planned:
• Await spontaneous onset of labour during the next four
weeks
• Reassure the woman that in 90% of cases the fetus is
spontaneously expelled during the waiting period with no
complicatons.
• If platelets are decreasing, four weeks have passed
without spontaneous labour, fibrinogen levels are low or
the woman request it,consider active management
(induction of labour)
37. Management (contd…)
If induction of labour is planned, assess the
cervix
• If the cervix is favourable (soft, thin, partly
dilated) labour using oxytocin.
• If the cervix is unfavourable(firm, thick,
closed) ripen the cervix.
Note: Do not rupture the membranes.
• If spontaneous labor does not occur within four weeks,
platelets are decreasing and the cervix is unfavourable,
ripen the cervix.
38. Complications
1. Psychological upset
2. Infection: Once the membranes rupture, infection,
especially by gas forming organism like CI. Welchi.
3. Blood coagulation disorders
4. During labour : Uterine inertia and PPH
39. Prevention of IUFD:
• Regular antenatal care
• To screen out the at-risk patients to
monitor carefully for the assessment of
fetal well being and to terminate the
pregnancy at the earliest evidences of fetal
compromise.
40. Morbid pathology of IUFD
• A dead fetus undergoes an aseptic destructive process
called maceration. The epiderm is the first structure to
undergo the process, whereby blistering and peeling off
of the skin occur. It appears between 12-24 hours after
death. The foetus becomes swollen and looks dusky
red. Gradually aseptic autolysis of the ligamentous
structure and liquefaction of the brain matter and other
viscera take place.
