Alice in Wonderland Syndrome, also referred to as Todd's Syndrome, is a neurological disorder that primarily affects children but can also occur in adults. It often presents itself as a distorted perception of objects or body parts. Individuals with AIWS may experience episodes where they perceive objects or their own body as either smaller or larger than they actually are. This perplexing perceptual alteration can be accompanied by a sense of disorientation.

1. Alice in Wonderland
Syndrome
BY SHAHRZAD ESMAEILI :1802103

3. Welcome to the Alice in Wonderland Syndrome ! In this
document, we'll explore the curious phenomenon that
affects perception, named after the famous Lewis Carroll's
story. Let's dive into the captivating world of Alice in
Wonderland and how it relates to a fascinating medical
condition.

5. Alice in Wonderland Cartoon:
The Alice in Wonderland cartoon, produced by Walt Disney
Productions in 1951, brought to life the imaginative tale of a
young girl named Alice. The story revolves around her
whimsical adventures through the nonsensical Wonderland.
This captivating cartoon showcases eccentric characters,
enchanting landscapes, and the fantastical atmosphere that
has made it a timeless classic.

6. Meet the memorable characters: this Alice in wonderland cartoon
introduces us to a variety of unforgettable characters that alice
encounters during her journey. From the white rabbit, the mad hatter,
the queen of hearts, to the Cheshire cat, each one contributes to the
unique charm of the story. Their peculiarities and unpredictable
behavior add to the sense of wonderment throughout the tale.

7. Alice in Wonderland Syndrome:
Now, let's delve into the intriguing link between the cartoon and
a peculiar medical condition known as Alice in Wonderland
Syndrome (AIWS). AIWS is a rare perceptual disorder that affects
individuals’ visual perception and sometimes the sense of time,
space, hearing, and touch. Let's explore the characteristics and
manifestations of this enigmatic condition.

9. What is Alice in Wonderland Syndrome?
Alice in Wonderland Syndrome, also referred to as Todd's Syndrome, is a neurological
disorder that primarily affects children but can also occur in adults. It often presents itself as
a distorted perception of objects or body parts. Individuals with AIWS may experience
episodes where they perceive objects or their own body as either smaller or larger than they
actually are. This perplexing perceptual alteration can be accompanied by a sense of
disorientation.

11. What are the Signs and Symptoms of Alice in
Wonderland Syndrome?
 The signs and symptoms may include:
• Visual distortions - such as seeing objects smaller or larger than normal,
and perceiving objects as being closer or farther from each other
• Unable to differentiate between colors
• Visual hallucinations
• Sensing straight lines and edges as wavy
• Unable to judge time
 Associated signs and symptoms of the underlying condition/disorder may
also be observed.

12. Nevertheless, in many individuals, the condition is
self-limiting and normal visual (sensory) perception
is restored within a short period of time

14. How is Alice in Wonderland Syndrome
Diagnosed?
Alice in Wonderland Syndrome is diagnosed through physical exams and
medical history evaluations (including seeking information about any trauma,
use of medications, or other conditions)
 Neurological, motor skills, and cognitive assessment may be undertaken
 Electroencephalogram (EEG); it is not considered to be a useful diagnostic
tool for AIWS
 Imaging studies including CT and MRI scans of the head and neck region
may be undertaken based on the healthcare provider’s evaluation, in order
to rule out other conditions

16. How can Alice in Wonderland Syndrome be Prevented?
 Presently, it may not be possible to prevent Alice in Wonderland
Syndrome. However, the following factors may help lower one’s risk for
acquiring the same:
• Undertaking early diagnosis and adequate treatment of any brain disorder,
including migraine headaches, brain tumors, and infections
• Avoiding the use of recreational drugs
• Wearing helmets and safety gear while participating in sports or while
driving to prevent head injury

17. References :
1. Todd J (1955) The syndrome of Alice in Wonderland. Can Med Assoc J 73(9):
701-704. 2. Bittmann S, Luchter E, Weissenstein A, Villalon G, Alieva EM (2020)
Micropsia in a 5 Years Old Son and Concomitant Telopsia of the Mother in
Teenager Age Supposing a Genetic Origin in Alice in Wonderland Syndrome.
Nov Res Sci 5(3). 3. Bittmann S, Luchter E, Weissenstein A, Bittmann L,
Moschüring-Alieva E, et al. (2020) Alice in Wonderland Syndrome: an update
of present data with a special view to body position, Traumatic and Genetic
Aspects. Journal of Regenerative Biology and Medicine 3(1): 1-5. 4.
Weissenstein A, Luchter E, Bittmann MA (2014) Alice in Wonderland
syndrome: A rare neurological manifestation with microscopy in a 6-year-old
child. J Pediatr Neurosci 9(3): 303-304. 5. Matsudaira T, Terada K, Takahashi Y
(2020) Alice in wonderland syndrome in an elderly patient with focal onset
epilepsy. J Clin Neurosci 76: 243-245.
6. Lanska DJ, Lanska JR (2018) The Alice-in-Wonderland Syndrome. Front
Neurol Neurosci 42: 142-150.