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Human Genetic Variation
1. • 2007
• Mario R. Capecchi, Martin J.
Evans and Oliver Smithies was rewarded
The Nobel Prize in Physiology or Medicine
• They discovered specific gene modification
using mice’s embryonic stem cells.
• With this discovery, it is possible to create
any DNA modifications
• This helps scientist to originate the role of
each individual gene
Mario R. Capecchi, Martin J. Evans and Oliver Smithies (from left to right)