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Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 67-year-old Male
 Patient admitted through Emergency Room via ambulance
from home
 After medical work-up patient was admitted to Medical-
Surgical unit
 Length of stay: 10/14/2015 -10/17/2015
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Advanced Alcoholic Cirrhosis
• Currently on the liver transplantation lists
 Type 2 Diabetes Mellitus
• Insulin required
 Chronic Kidney Disease
• Probable Stage III
 History of esophageal varices
• Banding Procedure
 History of Iron Deficient Anemia
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Mental Altered Status and Lethargy
 Pale Completions
 Significant Ascites
 Noted Lower Extremities Edema
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Afebrile, none of the following symptoms:
Shows no signs of chills, nausea, vomiting, diarrhea, rectal
bleeding, melena or hematoemesis
 No Respiratory discomfort
• No SOB, pleurisy, cough, wheezing
 No known Cardiac involvement
• No chest pain, irregular palpitation, dizziness, syncopal
episodes
 No headache, blurred vision, double vision, sore
throat, or tinnitus
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Significant ascites
 Noted chronic lower extremity edema
 Oxygen saturation with in normal limits on room air
 Mucous membranes appears somewhat dry
 No evidence of scleral icterus involvement
 Does not smoke
 Continuation abstinence from alcohol since 2003
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Pre-Analytical Work-up
 Patient Verification Process
 Blood culture
• Microbiology-yellow top
 Sodium citrate tubes
• Coagulation assay-blue top- PT PTT/INR
 Heparin tubes-
• Chemistry analysis -SST- Light green/Red top
(clot activator) -BMP, CMP, Lactic acid, CTNI,
Ammonia)
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 K3EDTA Tube
• Hematology and Blood Bank-confirmation-
lavender top
 K2 EDTA Tube
• Blood Bank -ABORH, T & S, major crossmatch units
requested- pink top
 Sodium oxalate/fluoride Tube
• Respiratory department-lactic acid on ice-gray top-
no tourniquet used
 Specimen Transportation to Laboratory
• Proper Inversion Performed
• Ammonia and lactic acid on ice
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 ↑ Monocytes-
• Severe Alcohol Cirrhosis
 ↓ WBC’s, RBC’s,
HGB, HCT, MCV,
MCH, and Platelets
 Indicative of
Microcytic,
hypochromic
Anemia
 Pancytopenia
• ↓in WBC’s, RBC’s,
Platelets in
peripheral blood
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 ↑Glucose
• Type 2 Diabetes Mellitus
 ↑Bun
• Severe renal impairment
 ↑Creatinine
• Impaired renal function
 ↓ Sodium
 ↓ Calcium
• Metabolic & electrolyte imbalance
 ↓ Total Protein
 ↓ Albumin
• Acute, Severe,
Chronic Liver &
Kidney disease
 ↓ Magnesium
• hypomagnesemia
 ↑ Lactic Acid
• Liver and Kidney Damage
 ↑ Ammonia-
• Advance Liver Disease and
Renal failure
 ↓ Ferritin
• Iron deficiency Anemia
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
ABO/RH Type A pos
Antibody Screen Positive
Antibody Panel Identification Anti-E, Panagglutinin, Warm autoantibody, Muliple Antibody, Postive autoantibody
Antigen E Type Negative
AHG/Direct Combs Testing IgG Positive
Elution Panel Studies (done by ARC) Panaggltuinin, Warm autoantibody
ABORH TYPE AND ANTIBODY PANEL RESULTS
TESTS RESULTS
Cross-Matched Packed RBC's Cell Transfusion Record
Date and Time 10/14/2015 10/14/2015 10/16/2015
Tranfusion Reaction
Started 1330 Started 1810 Started 1215 None
Stopped 1625 Stopped 2100 Stopped 1458 None
Amount Given 350 mL 350 mL 350 mL
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Cross-Matched Packed RBC's Cell Transfusion Record
Date and Time 10/14/2015 10/14/2015 10/16/2015
Tranfusion
Reaction
Started
18102110 Started 1330
Started
1215 None
Stopped 21100 Stopped 1625
Stopped
1458 None
Amount Given 350 mL 350 mL 350 mL
 Typed and Major Crossmatch Compatible
• 4 units of A Negative and 2 units of A positive Anti-E
Negative, Antigen E Negative
 3 Units Transfused
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 ↑Prothrombin Time
• Chronic Liver Cirrhosis/Severe
hepatocellular disease
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 ↑ Hyaline cast
 Granular casts
• Urinary stasis
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 GI Track/ Esophageal variceal suspected
 Blood Culture
• No growth after 48 hours
 Peritoneal Fluid
• No Growth after 72 hours
OCCULT BLOOD STOOL TEST
TEST 10/14/2015 Performed in ER by Physician 10/14/2015 @ 2326
Negative POSITIVE
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
IV Solutions and Drugs
 Dextrose 50%
-Fluid and nutrient replenish
 Naloxone HCL
-Opioid antagonist
 Ondansetron (zofran)
-Anti-nausea
 Rocephin
-Antibiotic
Insulin
 Glucagon (IM)
 Insulin Lispro
 Insulin Detemir (IM)
Oral Vitamins
 Folic acid
 Magoxide (magnesium oxide)
 Vitamin B-1
Sublinqual
 Nitroglycerin Sublingua
-Nitrates
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Hepatic Encephalopathy
• Advance Liver Cirrhosis
 Prerenal etiology
• Chronic Diuretic Use
 Acute Kidney Injury
• Sudden decrease kidney function within a few
hours
 Pancytopenia
• Aplastic anemia
 GI Track Bleed
• Underlying Varices bleeding
 Hypomagnesemia
• ↓Magnesium
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
 Very good, 80% to 90% survival rate IF liver
transplantation occurs
 Very poor, death will be imminent if liver
transplantation does not occur
 Possible kidney dialysis and/or eventually a
kidney transplant
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Blaney, K., & Howard, P. (2013). Basic & Applied Concepts of Blood Banking and
Transfusion Practices (3rd ed.). St. Louis, Missouri: Elsevier Mosby.
Blood Bank Guy.(1998-2015).Panagglutinin. Retrieved December 2, 2015, from
http://www.bbguy.org/education/glossary/index.aspx?alphabet=p&id=190
Betty, C. (2012). Normochromic Anemia: Biochemical, Membrane, and
Miscellaneous Red Blood Cell Disorders. In Hematology in Practice (2nd ed.,
pp. 98-109). Philadelphia, Pa 19103: F.A Davis Company.
Drugs.Com.(2000-2015). Dextrose 50 % Injection. Retrieved December 2, 2015,
from http://www.drugs.com/pro/dextrose-50-injection.html
Drugs.Com. (2000-2015). Glucagon. Retrieved December 2, 2015, from
http://www.drugs.com/mtm/glucagon.html
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Drugs.Com. (2000-2015). Insulin-determir. Retrieved December 2, 2015, from
http://www.drugs.com/mtm/insulin-detemir.html
Drugs.Com. (2000-2015). Insulin-lispro. Retrieved December 2, 2015 from
http://www.drugs.com/mtm/insulin-lispro.html
Drugs.Com. (2000-2015).Magnesium oxide. Retrieved December 2, 2015 from
http://www.drugs.com/search.php?searchterm=magnesium+oxide&a=1
Drugs.Com.(2000-2015). Naloxone HCL. Retrieved December 2, 2015, from
http://www.drugs.com/mtm/naloxone.html
Drugs.Com. (2000-2015). Nitroglycerin Sublingual. Retrieved December 2, 2015,
from http://www.drugs.com/mtm/nitroglycerin.html
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
Drugs. Com. (2000-2015). Ondansetron . Retrieved December 2,
2015, from http://www.drugs.com/.ondansetron.html
Drugs. Com. (2000-2015).Rocephin. Retrieved December 2, 2015,
from http://www.drugs.com/rocephin.htm
Drugs. Com.(2000-2015). Vitamin B-1. Retrieved December 2,
2015, from http;//www.drugs.com/mtm/vitamin_B-1.html
LabCE.(2015).Granular Casts. Retrieved December 2, 2015, from
https://www.labce.com/spg30119_granular_casts.aspx
McCall, R., & Tanhersley, C. (2012). Phlebotomy Essentials (5th ed.).
Baltimore, MD: Lippincott Williams & Wilkins, A Wolters
Kluwer business
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
McClain, C. (2002). Monocyte activation in alcoholic liver disease.
Retrieved December 3, 2015, from
http://www.alcoholjournal.org/article/S0741-8329 (02)00212-
4/abstract
Medline Plus (n.d). Magnesium Oxide. Retrieved December 2,
2015, from
https://www.nlm.nih.gov/medlineplus/druginfo/meds/a6010
74.html
National Kidney Foundation.(2015). ACUTE KIDNEY INJURY (AKI).
Retrieved December 3, 2015, from
https://www.kidney.org/atoz/content/AcuteKidneyInjury
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern
Maryland
Renee Backen
MLT-2015
Date: December 3, 2015
Professor Tiffany Gill
College of Southern Maryland
NIH U.S National Library of Medicine. (2015). Hepatic
encephalopathy. Retrieved December 3, 2015, from
https://www.nlm.nih.gov/medlineplus/ency/article/0003
02.htm
Strasinger, S., & Di Lorenzo, M. (2008). Urinalysis and Body
Fluids (5th ed.). Philadelphia, Pa 19103: F.A. Davis
Company.
Sunheimer, R., & Graves, L. (2011). Clinical
laboratory chemistry. Boston: Pearson.

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Mlt 2015 clinical case study updated

  • 1. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 2. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 3. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  67-year-old Male  Patient admitted through Emergency Room via ambulance from home  After medical work-up patient was admitted to Medical- Surgical unit  Length of stay: 10/14/2015 -10/17/2015
  • 4. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 5. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Advanced Alcoholic Cirrhosis • Currently on the liver transplantation lists  Type 2 Diabetes Mellitus • Insulin required  Chronic Kidney Disease • Probable Stage III  History of esophageal varices • Banding Procedure  History of Iron Deficient Anemia
  • 6. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 7. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Mental Altered Status and Lethargy  Pale Completions  Significant Ascites  Noted Lower Extremities Edema
  • 8. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Afebrile, none of the following symptoms: Shows no signs of chills, nausea, vomiting, diarrhea, rectal bleeding, melena or hematoemesis  No Respiratory discomfort • No SOB, pleurisy, cough, wheezing  No known Cardiac involvement • No chest pain, irregular palpitation, dizziness, syncopal episodes  No headache, blurred vision, double vision, sore throat, or tinnitus
  • 9. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Significant ascites  Noted chronic lower extremity edema  Oxygen saturation with in normal limits on room air  Mucous membranes appears somewhat dry  No evidence of scleral icterus involvement  Does not smoke  Continuation abstinence from alcohol since 2003
  • 10. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 11. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Pre-Analytical Work-up  Patient Verification Process  Blood culture • Microbiology-yellow top  Sodium citrate tubes • Coagulation assay-blue top- PT PTT/INR  Heparin tubes- • Chemistry analysis -SST- Light green/Red top (clot activator) -BMP, CMP, Lactic acid, CTNI, Ammonia)
  • 12. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  K3EDTA Tube • Hematology and Blood Bank-confirmation- lavender top  K2 EDTA Tube • Blood Bank -ABORH, T & S, major crossmatch units requested- pink top  Sodium oxalate/fluoride Tube • Respiratory department-lactic acid on ice-gray top- no tourniquet used  Specimen Transportation to Laboratory • Proper Inversion Performed • Ammonia and lactic acid on ice
  • 13. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 14. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 15. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 16. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  ↑ Monocytes- • Severe Alcohol Cirrhosis  ↓ WBC’s, RBC’s, HGB, HCT, MCV, MCH, and Platelets  Indicative of Microcytic, hypochromic Anemia  Pancytopenia • ↓in WBC’s, RBC’s, Platelets in peripheral blood
  • 17. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 18. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 19. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 20. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  ↑Glucose • Type 2 Diabetes Mellitus  ↑Bun • Severe renal impairment  ↑Creatinine • Impaired renal function  ↓ Sodium  ↓ Calcium • Metabolic & electrolyte imbalance  ↓ Total Protein  ↓ Albumin • Acute, Severe, Chronic Liver & Kidney disease  ↓ Magnesium • hypomagnesemia  ↑ Lactic Acid • Liver and Kidney Damage  ↑ Ammonia- • Advance Liver Disease and Renal failure  ↓ Ferritin • Iron deficiency Anemia
  • 21. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 22. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland ABO/RH Type A pos Antibody Screen Positive Antibody Panel Identification Anti-E, Panagglutinin, Warm autoantibody, Muliple Antibody, Postive autoantibody Antigen E Type Negative AHG/Direct Combs Testing IgG Positive Elution Panel Studies (done by ARC) Panaggltuinin, Warm autoantibody ABORH TYPE AND ANTIBODY PANEL RESULTS TESTS RESULTS Cross-Matched Packed RBC's Cell Transfusion Record Date and Time 10/14/2015 10/14/2015 10/16/2015 Tranfusion Reaction Started 1330 Started 1810 Started 1215 None Stopped 1625 Stopped 2100 Stopped 1458 None Amount Given 350 mL 350 mL 350 mL
  • 23. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Cross-Matched Packed RBC's Cell Transfusion Record Date and Time 10/14/2015 10/14/2015 10/16/2015 Tranfusion Reaction Started 18102110 Started 1330 Started 1215 None Stopped 21100 Stopped 1625 Stopped 1458 None Amount Given 350 mL 350 mL 350 mL  Typed and Major Crossmatch Compatible • 4 units of A Negative and 2 units of A positive Anti-E Negative, Antigen E Negative  3 Units Transfused
  • 24. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 25. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  ↑Prothrombin Time • Chronic Liver Cirrhosis/Severe hepatocellular disease
  • 26. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 27. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 28. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  ↑ Hyaline cast  Granular casts • Urinary stasis
  • 29. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 30. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  GI Track/ Esophageal variceal suspected  Blood Culture • No growth after 48 hours  Peritoneal Fluid • No Growth after 72 hours OCCULT BLOOD STOOL TEST TEST 10/14/2015 Performed in ER by Physician 10/14/2015 @ 2326 Negative POSITIVE
  • 31. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 32. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland IV Solutions and Drugs  Dextrose 50% -Fluid and nutrient replenish  Naloxone HCL -Opioid antagonist  Ondansetron (zofran) -Anti-nausea  Rocephin -Antibiotic Insulin  Glucagon (IM)  Insulin Lispro  Insulin Detemir (IM) Oral Vitamins  Folic acid  Magoxide (magnesium oxide)  Vitamin B-1 Sublinqual  Nitroglycerin Sublingua -Nitrates
  • 33. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 34. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Hepatic Encephalopathy • Advance Liver Cirrhosis  Prerenal etiology • Chronic Diuretic Use  Acute Kidney Injury • Sudden decrease kidney function within a few hours  Pancytopenia • Aplastic anemia  GI Track Bleed • Underlying Varices bleeding  Hypomagnesemia • ↓Magnesium
  • 35. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 36. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland  Very good, 80% to 90% survival rate IF liver transplantation occurs  Very poor, death will be imminent if liver transplantation does not occur  Possible kidney dialysis and/or eventually a kidney transplant
  • 37. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland
  • 38. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Blaney, K., & Howard, P. (2013). Basic & Applied Concepts of Blood Banking and Transfusion Practices (3rd ed.). St. Louis, Missouri: Elsevier Mosby. Blood Bank Guy.(1998-2015).Panagglutinin. Retrieved December 2, 2015, from http://www.bbguy.org/education/glossary/index.aspx?alphabet=p&id=190 Betty, C. (2012). Normochromic Anemia: Biochemical, Membrane, and Miscellaneous Red Blood Cell Disorders. In Hematology in Practice (2nd ed., pp. 98-109). Philadelphia, Pa 19103: F.A Davis Company. Drugs.Com.(2000-2015). Dextrose 50 % Injection. Retrieved December 2, 2015, from http://www.drugs.com/pro/dextrose-50-injection.html Drugs.Com. (2000-2015). Glucagon. Retrieved December 2, 2015, from http://www.drugs.com/mtm/glucagon.html
  • 39. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Drugs.Com. (2000-2015). Insulin-determir. Retrieved December 2, 2015, from http://www.drugs.com/mtm/insulin-detemir.html Drugs.Com. (2000-2015). Insulin-lispro. Retrieved December 2, 2015 from http://www.drugs.com/mtm/insulin-lispro.html Drugs.Com. (2000-2015).Magnesium oxide. Retrieved December 2, 2015 from http://www.drugs.com/search.php?searchterm=magnesium+oxide&a=1 Drugs.Com.(2000-2015). Naloxone HCL. Retrieved December 2, 2015, from http://www.drugs.com/mtm/naloxone.html Drugs.Com. (2000-2015). Nitroglycerin Sublingual. Retrieved December 2, 2015, from http://www.drugs.com/mtm/nitroglycerin.html
  • 40. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Drugs. Com. (2000-2015). Ondansetron . Retrieved December 2, 2015, from http://www.drugs.com/.ondansetron.html Drugs. Com. (2000-2015).Rocephin. Retrieved December 2, 2015, from http://www.drugs.com/rocephin.htm Drugs. Com.(2000-2015). Vitamin B-1. Retrieved December 2, 2015, from http;//www.drugs.com/mtm/vitamin_B-1.html LabCE.(2015).Granular Casts. Retrieved December 2, 2015, from https://www.labce.com/spg30119_granular_casts.aspx McCall, R., & Tanhersley, C. (2012). Phlebotomy Essentials (5th ed.). Baltimore, MD: Lippincott Williams & Wilkins, A Wolters Kluwer business
  • 41. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland McClain, C. (2002). Monocyte activation in alcoholic liver disease. Retrieved December 3, 2015, from http://www.alcoholjournal.org/article/S0741-8329 (02)00212- 4/abstract Medline Plus (n.d). Magnesium Oxide. Retrieved December 2, 2015, from https://www.nlm.nih.gov/medlineplus/druginfo/meds/a6010 74.html National Kidney Foundation.(2015). ACUTE KIDNEY INJURY (AKI). Retrieved December 3, 2015, from https://www.kidney.org/atoz/content/AcuteKidneyInjury
  • 42. Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland Renee Backen MLT-2015 Date: December 3, 2015 Professor Tiffany Gill College of Southern Maryland NIH U.S National Library of Medicine. (2015). Hepatic encephalopathy. Retrieved December 3, 2015, from https://www.nlm.nih.gov/medlineplus/ency/article/0003 02.htm Strasinger, S., & Di Lorenzo, M. (2008). Urinalysis and Body Fluids (5th ed.). Philadelphia, Pa 19103: F.A. Davis Company. Sunheimer, R., & Graves, L. (2011). Clinical laboratory chemistry. Boston: Pearson.

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  11. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html McCall, R., & Tanhersley, C. (2012). Phlebotomy Essentials (5th ed.). Baltimore, MD: Lippincott Williams & Wilkins, A Wolters Kluwer business.
  12. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html McCall, R., & Tanhersley, C. (2012). Phlebotomy Essentials (5th ed.). Baltimore, MD: Lippincott Williams & Wilkins, A Wolters Kluwer business.
  13. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  14. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  15. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  16. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html McClain, C. (2002). Monocyte activation in alcoholic liver disease. Retrieved December 3, 2015, from http://www.alcoholjournal.org/article/S0741-8329 (02)00212-4/abstract graphic image taken from Carson-DeWitt, Rosalyn.(2006). Pernicious Anemia. Gale Encyclopedia of Medicine, 3rd ed.. 2006. Retrieved December 3, 2015 from Encyclopedia.com: http://www.encyclopedia.com/doc/1G2-3451601237.html
  17. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  18. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  19. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  20. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html Sunheimer, R., & Graves, L. (2011). Clinical laboratory chemistry. Boston: Pearson.
  21. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  22. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  23. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  24. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  25. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  26. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  27. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  28. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html Bottom graphic image take from LabCE.(2015).Granular Casts. Retrieved December 2, 2015, from https://www.labce.com/spg30119_granular_casts.aspx http://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html Strasinger, S., & Di Lorenzo, M. (2008). Urinalysis and Body Fluids (5th ed.). Philadelphia, Pa 19103: F.A. Davis Company. LabCE.(2015).Granular Casts. Retrieved December 2, 2015, from https://www.labce.com/spg30119_granular_casts.aspx (graphic image)
  29. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  30. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  31. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  32. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html Drugs.Com.(2000-2015). Dextrose 50 % Injection. Retrieved December 2, 2015, from http://www.drugs.com/pro/dextrose-50-injection.html Drugs.Com. (2000-2015). Glucagon. Retrieved December 2, 2015, from http://www.drugs.com/mtm/glucagon.html Drugs.Com. (2000-2015). Insulin-determir. Retrieved December 2, 2015, from http://www.drugs.com/mtm/insulin-detemir.html Drugs.Com. (2000-2015). Insulin-lispro. Retrieved December 2, 2015 from http://www.drugs.com/mtm/insulin-lispro.html Drugs.Com. (2000-2015).Magnesium oxide. Retrieved December 2, 2015 from http://www.drugs.com/search.php?searchterm=magnesium+oxide&a=1 Drugs.Com.(2000-2015). Naloxone HCL. Retrieved December 2, 2015, from http://www.drugs.com/mtm/naloxone.html Drugs.Com. (2000-2015). Nitroglycerin Sublingual. Retrieved December 2, 2015, from http://www.drugs.com/mtm/nitroglycerin.html Drugs.Com. (2000-2015). Ondansetron . Retrieved December 2, 2015, from http://www.drugs.com/.ondansetron.html Drugs.Com. (2000-2015).Rocephin. Retrieved December 2, 2015, from http://www.drugs.com/rocephin.htm Drugs.Com.(2000-2015). Vitamin B-1. Retrieved December 2, 2015, from http;//www.drugs.com/mtm/vitamin_B-1.html
  33. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  34. NIH U.S National Library of Medicine. (2015). Hepatic encephalopathy. Retrieved December 3, 2015, from https://www.nlm.nih.gov/medlineplus/ency/article/000302.htm National Kidney Foundation.(2015). ACUTE KIDNEY INJURY (AKI). Retrieved December 3, 2015, from https://www.kidney.org/atoz/content/AcuteKidneyInjury Ciesla, B. (2012). Hematology in practice (2nd ed). Philadelphia, Pa.: F.A. Davis Company. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
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  36. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  37. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  38. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
  39. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html Bottom graphic image take from LabCE.(2015).Granular Casts. Retrieved December 2, 2015, from https://www.labce.com/spg30119_granular_casts.aspx http://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html Strasinger, S., & Di Lorenzo, M. (2008). Urinalysis and Body Fluids (5th ed.). Philadelphia, Pa 19103: F.A. Davis Company.
  40. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html
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  42. Graphic image on top Download Power Point. (n.d.). Best Test Tube PowerPoint. the template. Retrieved December 3, 15, 2015, from Templateshttp://www.downloadpowerpointtemplates.com/Medical/Blue-test-tube-Medical-Powerpoint--the-Templates.html