Vip Call Girls Anna Salai Chennai 👉 8250192130 ❣️💯 Top Class Girls Available
Q7 JONES CRITERIA SLIDESHARE PPT.pdf
1. 2015 Jones criteria for Diagnosis of Rheumatic fever
Presenter
Dr Praveen Gupta
Moderator
DR Santhosh satheesh
Department of cardiology
JIPMER
Pondicherry
India
13.02.2018
1
3. Diagnosis of rheumatic fever
Development of the first clinical criteria for the diagnosis of ARF
known as the ‘Jones Criteria’
Allowed RF to be diagnosed uniformly in multicenter studies of RF
3
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
4. Jones criteria for the diagnosis of rheumatic fever
Two major, or one major and two minor manifestations evidence of rheumatic activity
Previous history of definite RF or RHD was considered a major criterion, diagnosis of a
recurrence of RF did not require strict application of these guidelines, and minor
manifestations were considered sufficient for the diagnosis.
Preceding streptococcal infection has been emphasized for diagnosis of RF
Insidious and chronic carditis, chorea, were exempted to demonstrate streptococcal etiology
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
4
5. Revising the standard
Decline in ARF in the USA motivated four revisions to Dr Jones’ criteria
High specificity at the cost of lowered sensitivity
Changes were appropriate for high-income, Low-prevalence countries,
1992 revision of the Jones criteria lacked sufficient sensitivity in high prevalence regions
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
5
6. Jones criteria for the diagnosis of rheumatic fever
Australia and New Zealand , publish ARF diagnostic guidelines, diverged from Jones criteria
WHO released its own version
Other countries followed suit, and the Jones criteria risked becoming a relic of history
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
6
7. 7
World Health Organization. Rheumatic Fever and Rheumatic Heart Disease: Report of a WHO Expert Consultation,
Geneva, 29 October-1 November, 2001. World Health Organization; 2004 Feb 4.
8. 8
World Health Organization. Rheumatic Fever and Rheumatic Heart Disease: Report of a WHO Expert Consultation,
Geneva, 29 October-1 November, 2001. World Health Organization; 2004 Feb 4.
9. 2015 Jones criteria
In 2012, AHA took on another revision
Include prominent authors working in high prevalence regions
Guidelines, in 2015, acknowledge the importance of including pretest probability in
weighing sensitivity versus specificity, and
Separate guidelines for low-risk and moderate-to high- risk populations
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
9
10. 2015 Jones criteria
This revision also embraces echocardiography, recommending its use in all
populations, when available, for the diagnosis of rheumatic carditis
2015 revision will ensure the Jones criteria are re-established as the international
gold standard for ARF diagnosis
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
10
11. 2015 JONES CRITERIA
AHA criteria categories manifestations of ARF into major and minor criteria
First episode of ARF is diagnosed when there is recent streptococcal infection in
addition to either two major or one major and two minor criteria
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
11
12. Three main changes in Jones diagnostic criteria
Risk stratification
Echocardiographic detection of subclinical carditis
Joint manifestations
12
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
13. Separation into low-risk and moderate/high-risk populations
The burden of ARF is distributed unequally around the globe
High-income countries have seen a near eradication of disease
Low-income/low-resource countries, or poorer populations within wealthy
countries, have seen very little change in ARF incidence
Common in endemic regions to see hyperendemic disease patterns
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
13
14. Separation into low-risk and moderate/high-risk populations
Data from high-prevalence settings such as Australia that the Clinical
manifestations of ARF, in particular joint presentations and peak fever, may be
substantially less dramatic, and thus less clinically obvious, compared with those
seen in low-risk settings.
Australian guidelines were the first to consider high-risk and low-risk populations
separately, emphasising high sensitivity among those at greatest risk and high
specificity for those at lower risk.
The 2015 Jones criteria revision has embraced this risk-stratified approach.
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
14
15. Separation into low-risk and moderate/high-risk populations
The 2015 revision defines low risk (ARF incidence <2 per 100 000 school-aged
children per year or an all-age prevalence of RHD of ≤1 per 1000 population per
year),
Children not clearly from a low-risk ARF population should be considered at
moderate-to-high risk
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
15
16. Addition of subclinical carditis as a major manifestation
Clinical carditis been defined as an audible murmur consistent with AR/MR
In 2000, interest was growing in the importance of subclinical carditis, or clinically silent
valvular involvement only detectable through echocardiography, as an indicator of ARF
Substantial prevalence and significance of subclinical carditis among patients with ARF
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
16
17. Addition of subclinical carditis as a major manifestation
These findings led to the inclusion of echocardiography for the evaluation of patients with
suspected or confirmed ARF and the addition of subclinical carditis as a major manifestation
for all populations in the 2008 New Zealand guidelines and high-risk populations in the 2012
Australian guidelines.
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
17
18. Addition of subclinical carditis as a major manifestation
2015 Jones revision made similar recommendations: either clinical or subclinical carditis
qualifies as a major manifestation in low-risk and high-risk populations
The criteria recommend that, when possible, all patients with confirmed or suspected ARF
undergo echocardiography to evaluate for carditis, with those who are negative on first
evaluation undergoing repeated study to assess for evolving cardiac diseases
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
18
19. Addition of subclinical carditis as a major manifestation
Diagnosis of subclinical carditis is made based on specific recommendations for pathological
Mitral Regurgitation/ Aortic Regurgitation (MR/AR)
Normal echocardiogram can rule out a diagnosis of carditis made through clinical auscultation
(improving specificity)
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
19
20. Joint manifestations
As arthritis/arthralgia can be seen in a wide spectrum of diseases,
Inclusion of different forms of joint involvement in Jones criteria, subject of debate
Many patients self-medicate which effectively treat the arthritis/ arthralgia
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
20
21. Joint manifestations
Classic migratory polyarthritis is not the only form of joint involvement in ARF
In high-risk populations, it results in missed cases of ARF
In high-risk populations aseptic monoarthritis is an important manifestation of ARF
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
21
22. Joint manifestations
Monoarthritis in 16– 18% of children with ARF
27 out of 75 children with monoarthritis who would have met criteria for ARF had
monoarthritis been included as a major criterion
55% went on to develop either ARF or RHD
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
22
23. Joint manifestations
2015 Jones criteria revision includes polyarthritis, monoarthritis and polyarthralgia as major
criteria and monoarthralgia as a minor criterion in moderate-risk and high-risk populations.
No change has been made to the diagnosis of joint involvement in low-risk populations
Differential diagnoses for joint involvement have first been excluded
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
23
24. Minor criteria
To improve the sensitivity of ARF diagnosis in moderate to high-prevalence population
Fever cut-off was lowered to 38.0° C,
ESR >30 mm/h in moderate-risk to high-risk populations ( >60 mm/h in low-risk)
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
24
25. ARF recurrences
Patients with history of ARF at high risk for recurrences
2015 revision provide direct guidance, requiring that two major, one major and two minor, or
three minor criteria be met in a patient with a reliable past history of ARF/RHD and
documentation of a recent streptococcal infection
Excluding more likely diagnoses, when only minor manifestations are present
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
25
26. Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
26
27. Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11. 27
28. Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
28
29. Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
29
30. Potential impact on revised jones criteria 2015
2015 Jones criteria would translate into national governments raising the priority level of
ARF/RHD within their health agendas and establishing national programmes for ARF/ RHD
prevention.
Help answer , Where are all the children with ARF?
Single criteria, ensuring uniform system for diagnosis and data collection across research sites
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
30
31. Increased research potential
Will remain imperfect because diagnosis still relies on a clinical diagnostic algorithm.
Always be potential for imperfect specificity and overinclusive diagnoses, as well as
imperfect sensitivity and missed cases of ARF
Have the potential to increase case detection, with more internationally accepted guidelines
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
31
32. Take home message
2015 revision has re-established the Jones criteria for ARF diagnosis in all settings
The guidelines stay true to the approach of Dr Jones by
High specificity for ARF in low-risk populations
Sensitive guidelines for use in moderate/high-risk settings
Beaton A, Carapetis J. The 2015 revision of the Jones criteria for the diagnosis of acute rheumatic fever: implications
for practice in low-income and middle-income countries. Heart Asia. 2015 Jul 1;7(2):7-11.
32