2. Heart Failure – Global Burden
Ponikowski, P, et al. Heart Failure – preventing disease and death worldwide. 2014. Available at: http://www.escardio.org/communities/HFA/Documents/whfa-whitepaper.pdf , 2014.
North America
Canada 1.5%
USA 1.9%
Europe ~1.2%
France 2.2%
UK 1.3%
Asia
China 1.3%
Japan -1%
Malaysia 6.7%
Singapore 4.5%
Latin America
No population-based
estimates
Adapted from Ponikowski et al, 2014
*HF or swollen limbs
Africa
No population-
based estimates
Middle East
Oman 0.5%
Australasia
Australia* 1.3%
4. Heart Failure Prevalence - Expected to
Continue Increasing
1. Mozaffarian D, et al; Circulation 2015;131(4):e29-e322. 2. Global Burden of Disease Study 2013 Collaborators, Lancet. 2015 Nov 28;386(10009):2145-91
5. Mean Age of Patients: 53 Years
In-Hospital Mortality: 30.8%
Post Discharge Mortality (6 months): 26.3%
Heart Failure – A Bigger Challenge in India
Fortheuseonlyofhealthcare
practitioner,hospital,or
laboratory
Global
India
Mean Age of Patients: 73 Years
In-Hospital Mortality: 3.8%
Post Discharge Mortality (6 months): 8.6%
Patients With Heart Failure In India
• Affected at a Younger Age
• Have a Very High Mortality Both In-Hospital and also After Discharge
Seth S, et al. J Pract Cardiovasc Sci 2015;1:35-8.
6. Key Facts for Heart Failure - Summary
Fortheuseonlyofhealthcare
practitioner,hospital,or
laboratory
Chaturvedi V, et al. J Pract Cardiovasc Sci 2016;2:28-35.
7. Chronic HF - Associated with a Devastating
Burden
Despite the introduction of treatments,
the mortality rate for patients with chronic
HF is about 50% at 5 years post-diagnosis1–7
HRrEF: Heart failure with reduced ejection fraction; HFpEF: Heart failure with preserved ejection fraction; LVEF: left ventricular ejection fraction
1. Owan et al. N Engl J Med 2006;355:251–9; 2. Roger et al. JAMA 2004;292:344–50; 3. Levy et al. N Engl J Med 2002;347:1397–402; 4. McMurray et al. Eur Heart J 2012;33:1787–847; 5.
Yancy et al. Circulation 2013;128:e240–327; 6. Loehr et al. Am J Cardiol 2008;101:1016–22; 7. Askoxylakis et al. BMC Cancer 2010;10:105
Editor's Notes
HF is a major and growing public health problem. It is one of the most important causes of morbidity and mortality in the industrialized world, with lower survival rates than bowel, breast or prostate cancers. Heart failure is also the most common cause of hospitalization in patients aged 65 years and over.
It is estimated that 1–2% of people in developed countries suffer from heart failure. In Europe, there are 15 million adult patients with heart failure (which equates to around 2% of the population), and in the United States, there are 6.3 million patients living with this condition (again, this equates to around 2% of the population). In the United States this figure is expected to increase by 37% by 2030. The prevalence of heart failure is highest in patients aged over 65 years, and rises to 10–20% among people aged over 70 years