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Principles of Management of
Burns
By
Dr. Olofin K. E
Registrar Casualty Dept.
UATH
10/30/2023 1
Outline
ā€¢ Introduction/Definition
ā€¢ Epidemiology
ā€¢ Anatomy of the skin
ā€¢ Pathology/Pathophysiology of burns
ā€¢ Classification/wound estimation
ā€¢ Management
ā€¢ Complications
ā€¢ Prognosis
ā€¢ Prevention
ā€¢ Conclusion
ā€¢ References
10/30/2023 2
Introduction/Definition
Definition:
Injury to living tissue arising from exposure to heat, friction, electricity,
radiation, chemicals or cold
ā€¢ Non-fatal burn injuries are a leading cause of morbidity.
ā€¢ 2/3 of all burns happen at home
ā€¢ Burn injuries continue to be a major source of mortality and
morbidity in low- and middle-income countries of the world, of which
Nigeria is a part.
10/30/2023 3
Introduction
ā€¢ Flame is emerging as the predominant cause of burns, and burn
injury is occurring increasingly away from the domestic setting.
ā€¢ The severity of the injuries is also increasing.
ā€¢ Several challenges militate against optimal care for burn victims.
ā€¢ Burn injuries continue to contribute significantly to the burden of
disease in Nigeria.
ā€¢ Avoidable complications are common and mortality remains high.
10/30/2023 4
Epidemiology
ā€¢ 4.8% of trauma deaths in Nigeria
ā€¢ 6.7% of surgically related deaths.
ā€¢ In children, burns and scalds are the 4th commonest cause of
trauma < road traffic accidents < accidental falls < bites.
ā€¢ Over 95% of fatal fire-related burns occurred in low- and
middle-income countries
ā€¢ Chemical burns constitute 6.3% of burns in Enugu and 5% in
Ibadan
ā€¢ Electrical burn injuries have an incidence of less than 1% in
children and 2.8-4.6% in all burn
10/30/2023 5
Epidemiology cont.ā€¦
ā€¢ In India, over 1 000 000 people are moderately or severely burnt
every year.
ā€¢ In Bangladesh, Colombia, Egypt and Pakistan, 17% of children with
burns have a temporary disability and 18% have a permanent
disability.
ā€¢ Burns are the second most common injury in rural Nepal, accounting
for 5% of disabilities.
ā€¢ In 2008, over 410 000 burn injuries occurred in the United States of
America, with approximately 40 000 requiring hospitalization.
10/30/2023 6
Anatomy of the skin
10/30/2023 7
The skin:
Largest organ
15% of total body weight
1.7 m2
Essential for:
ā€¢ Thermoregulation
ā€¢ Prevention of fluid loss by evaporation
ā€¢ Barrier against infection
ā€¢ Protection from environment provided by sensory information
ā€¢ Others- social etc.
10/30/2023 8
Pathology of burns
ā€¢ Fire/flames, Contact with hot liquids, hot/cold solid materials
induce cellular damage via transfer of energy directly leads to
coagulation necrosis.
ā€¢ Chemical and electrical burns cause injury via cell membrane
damage in addition to thermal injury.
ā€¢ Depth of Injury depends on 3 factors
1. Causative agents
2. Temperature at which skin exposed
3. Duration of Exposure.
10/30/2023 9
Pathology of burns
10/30/2023 10
Pathology cont.ā€¦
10/30/2023 11
Pathology cont.ā€¦
10/30/2023 12
Pathophysiology
Systemic Effects of Burns
1. Cardiovascular system
2. Renal system
3. Respiratory tract changes
4. Gastrointestinal tract changes
5. Central nervous system
changes
6. Hematological changes
7. Metabolic changes
8. Endocrine changes
9. Immune system changes
10/30/2023 13
Pathophysiology cont.ā€¦
Post Burn Metabolic Phenomena
Two Distinct phase of metabolic changes observed in post burns.
Ebb phase
ā€¢ It occurs within the first 48 hours of injury
ā€¢ Characterized by decrease in cardiac output, oxygen consumption
and metabolic rate, as well as impaired glucose tolerance
The flow phase
ā€¢ These metabolic variables gradually increase within the first 5 days
post injury to a plateau phase
10/30/2023 14
Pathophysiology cont.ā€¦
Post Burn Squela
ā€¢ Cardiac out put increases by 1.5 times
ā€¢ Liver size increases by 225%
ā€¢ Muscle protein is degraded much faster than it is synthesized.
ā€¢ The net protein loss causes loss of lean body mass and severe muscle
wasting.
ā€¢ 10% loss ā€“ Immune Dysfunction
ā€¢ 20% loss ā€“ Decrease wound healing
ā€¢ 30% loss ā€“ Increased risk of Pneumonia & Pressure sores
ā€¢ 40% loss ā€“ Death
10/30/2023 15
Pathophysiology cont.ā€¦
10/30/2023 16
Classifications
-Depth -Types/ Source of energy - Extent
Depth
ā€¢ Superficial
ā€¢ Partial thickness
ā€¢ Superficial
ā€¢ Deep
ā€¢ Full thickness
ā€¢ Mixed
10/30/2023 17
Superficial burns
ā€¢ old 1st degree
ā€¢ Epidermis only
ā€¢ Resembles Sunburn
ā€¢ No blistering
ā€¢ Capacity to heal
completely
10/30/2023 18
Superficial partial thickness
ā€¢ Epidermal and papillary layers
of dermis involved
ā€¢ Blister formation
ā€¢ Rupture causes weeping moist
injury
10/30/2023 19
Deep Partial Thickness
ā€¢ old 2nd degree
ā€¢ through epidermis, into reticular
dermis
ā€¢ Pale or Pink, moist, blisters, very
painful
ā€¢ Some capacity to heal
10/30/2023 20
10/30/2023 21
Full thickness burn
ā€¢ old 3rd degree (and 4th)
ā€¢ Through epidermis, dermis and
connective tissue
ā€¢ Appears waxy white, leathery gray or
charred black and dry and is not painful
ā€¢ Has various colours
10/30/2023 22
10/30/2023 23
Classification cont.ā€¦
Types/source
ā€¢ Thermal: Contact, flame, Scald,
ā€¢ Electrical- AC,DC
ā€¢ Chemical
ā€¢ Sun burn
ā€¢ Lightening
ā€¢ Radiation
ā€¢ Laser
ā€¢ Frostbite
10/30/2023 24
Classification cont.ā€¦
Extent
Assessment of extent of burn wound
ā€¢ Rule of Nines:
ā€¢ Quick estimate of percent of burn
ā€¢ Lund and Browder:
ā€¢ More accurate assessment tool
ā€¢ Useful chart for children ā€“ takes into account the head size proportion.
ā€¢ Rule of Palms:
ā€¢ Good for estimating small patches of burn wound
10/30/2023 25
Rule of Nines
10/30/2023 26
Lund Browder Chart
10/30/2023 27
American Burn Association Severity Classification
10/30/2023 28
Management
Prehospital care
Principles
1. Ensure rescuer safety
2. Stop the burning process
3. Check for other injuries
4. Cool the burn
5. Give oxygen
6. Elevate
10/30/2023 29
Management
ATLS protocol
Primary survey
ā€¢ Airway: Early recognition of airway compromise, intubation.
ā€¢ Breathing: Pattern of breathing. Breathing?
ā€¢ Circulation: vascular access, monitor device, blood pressure.
ā€¢ Disability: other injuries; fractures, abdominal injury or
neurological deficit.
ā€¢ Exposure: out of clothes, exposure of all orifices.
ā€¢ Fluid resuscitation:
10/30/2023 30
Management cont.ā€¦
Secondary survey
Full history
ā€¢ Biodata
ā€¢ Cause of the burn
ā€¢ Time of injury
ā€¢ Place of the occurrence (closed space, presence of chemicals,
noxious fumes)
ā€¢ Likelihood of associated trauma (explosion,ā€¦)
ā€¢ Pre-hospital interventions
10/30/2023 31
Management cont.ā€¦
ā€¢ Detection of the mechanism of injury.
ā€¢ Consideration of abuse
ā€¢ Possibility of carbon monoxide intoxication
Full examination
ā€¢ TBSA, Burn depth, inhalational injury
ā€¢ Concomitant injury, deformity, dx habitus
ā€¢ Height and weight.
10/30/2023 32
Management cont.ā€¦
Indications For admission
ā€¢ Major Burns
ā€¢ Special areas- face, hand, perineum, joints, inhalational
ā€¢ Poly-trauma
ā€¢ Co- morbidities- DM, SCD, CVA
ā€¢ Domestic abuse (slightest suspicion)
10/30/2023 33
Management cont.ā€¦
Investigations
ā€¢ Electrolytes
ā€¢ Blood gases
ā€¢ Glucose
ā€¢ Protein
ā€¢ Haemoglobin (must be kept >12 g%)
ā€¢ Bronchoscopy, X-rays
10/30/2023 34
Management cont.ā€¦
Goals of management
4Rs: revive , restore, repair and rehabilitate
ā€¢ Maintaining body fluids & electrolytes
ā€¢ Relieving pain
ā€¢ Preventing/Treating infection
ā€¢ Nutrition
ā€¢ Early wound cover/ healing/surgery
ā€¢ Rehabilitation
10/30/2023 35
Management cont.ā€¦
Fluid Resuscitation
ā€¢ Goal- Maintain tissue perfusion
ā€¢ Burns > 10% TBSA for children
ā€¢ Burns > 15% TBSA for Adults
ā€¢ Parkland, Brookes, Galveston, Shriners
ā€¢ Crystalloids or colloids?
ā€¢ Fluid monitoring
ā€¢ Urine output, blood pressure ,central venous pressure, heart rate
ā€¢ Urine output- 30-50ml/hr. 0.5 - 1.0 ml/kg/hr.
ā€¢ Input/ output chart recorded hourly!!!
10/30/2023 36
Management cont.ā€¦
Resuscitation Formulaā€™s
ā€¢ total area
FORMULA CRYSTALLOID COLLOID
Parkland 4 mL/kg per %
TBSA burn
None None
Brooke 1.5 mL/kg/%
TBSA burn
0.5 mL/kg per
% TBSA burn
Galveston
(pediatric)
5000 mL/m 2
burned area +
1500 mL/m 2
10/30/2023 37
Management cont.ā€¦
Parklands
ā€¢ Commonest
ā€¢ 1/2 in first 8hrs post burn
ā€¢ 1/2 in next sixteen hrs.
ā€¢ Subsequently, Daily requirements plus ongoing losses after 24hrs
ā€¢ Ongoing losses = 1cc/kg x TBSA
ā€¢ Monitor urinary output!!! As determinant of adequate resuscitation
(except in ARF)
10/30/2023 38
Management cont.ā€¦
Pain management
ā€¢ Pain- Hyperalgesia develops from exposed viable and growing nerve
endings
ā€¢ Pain with time becomes learned and is psychological and difficult to
manage
ā€¢ Pain is REAL to the patient
ā€¢ IV injections not advised when burns exceeds 10% TBSA
10/30/2023 39
Management cont.ā€¦
Analgesics-
ā€¢ Opioids- morphine(adults). Pethidine , PCM
ā€¢ NSAIDS-
ā€¢ Oral ketamine
ā€¢ Anesthesia for dressings
ā€¢ Psychotherapy, encouragement
ā€¢ Good dressing techniques
ā€¢ Soak dressings-shower
ā€¢ Products- Non Adherent, Fewer intervals
ā€¢ Early mobilization
10/30/2023 40
Management cont.ā€¦
Surgery
ā€¢ Debridement
ā€¢ Fasciotomy
ā€¢ For compartment syndrome
ā€¢ Escharoctomy
ā€¢ Tangential excision + STSG
ā€¢ Others as indicated
10/30/2023 41
Management cont.ā€¦
10/30/2023 42
Management cont.ā€¦
Burn Wound dressings
Principles:
ā€¢ Full-thickness and deep-dermal burns need antibacterial dressings to
delay colonization prior to surgery
ā€¢ Superficial burns will heal and need simple dressings
ā€¢ An optimal healing environment can make a difference to outcome in
borderline-depth burns
10/30/2023 43
Management cont.ā€¦
wound dressing
ā€¢ Regular intervals as determined by the need (not by staffing)
ā€¢ Give analgesics I.V 30 mins before procedure ( or proceed with
psychotherapy)
ā€¢ Layered removal of dressing
ā€¢ Debride when required
ā€¢ Clean with normal saline
ā€¢ Dab dry
ā€¢ Apply topical antibiotic
ā€¢ Layered dressings applied systematically
10/30/2023 44
Management cont.ā€¦
Dressings can be occlusive or open
Benefits of occlusive dressing
ā€¢ Protects against infection
ā€¢ Reduces pain- nerve endings exposed to air is painful
ā€¢ Providers a moist environnent for re-epithelisation
ā€¢ Nursing care is easier/ not messy like open dressing
ā€¢ Reduces need for frequent dressings with pain and pressure on
nursing personnel
10/30/2023 45
Management cont.ā€¦
Benefits of Open Dressings
ā€¢ Easy , Quicker
ā€¢ Dressing procedure less painful
ā€¢ Cheaper
ā€¢ Easy access to assess wounds for infection
ā€¢ Great for hot tropical weather
ā€¢ Difficult to move patient if extensive
ā€¢ Messy on beddings
ā€¢ More difficult to control hypothermia
ā€¢ Requires strict control of environment, visitors
10/30/2023 46
Management cont.ā€¦
Dressing agents
Full-thickness burns and obvious deep dermal wounds
Nanocrystalline silver
ā€¢ Silver sulphadiazine cream: 1%broad spectrum, not painful, yellow
pseudo eschar. Self limiting leucopenia
ā€¢ Silver nitrate solution (0.5%)
ā€¢ Mafenide asetate cream or 5% soln. Painful. Permeates eschars.
Carbonic anhydrase inhibitor causes acidosis
ā€¢ Cerium nitrate
10/30/2023 47
Management cont.ā€¦
Superficial partial-thickness wounds and mixed ā€“depth wounds
1. Exposure
2. Mefix
3. mepitel
4. Hydrocolloid
5. Biobrane
6. Amniotic membrane
ā€¢ Bacitracin: chlorhexidine
ā€¢ Povidone iodine
ā€¢ Bactroban:Mupirocin ā€“ MRSA
10/30/2023 48
Management cont.ā€¦
Skin Substitutes
ā€¢ Transcyte- cultured human fibroblasts in semi-permiable membrane
on nylon matrix
ā€¢ Alloderm
ā€¢ Integra
ā€¢ CEA ā€“ cultured epithelial autograft
10/30/2023 49
Management cont.ā€¦
Blisters
To rupture or to leave?
ā€¢ Controversial
ā€¢ Blister fluid contains vasoactive mediators-
progression of the ischemic zone, and inhibit healing.
ā€¢ The intact blister also serves as a physiologic dressing
ā€¢ Blisters larger than several inches in diameter are
most likely to rupture and should be removed.
ā€¢ Small blisters- Can leave
ā€¢ Large blister- Rupture
ā€¢ Blisters over joints- Rupture
10/30/2023 50
Management cont.ā€¦
Hydrotherapy Cart Shower
10/30/2023 51
Management cont.ā€¦
Nutrition
ā€¢ Aim- Achieve a positive nitrogen balance
ā€¢ Correct deficit
ā€¢ Premorbid, pre referral
ā€¢ Correct on-going losses
ā€¢ Chronic catabolic state
ā€¢ Maintenance
ā€¢ Daily requirements
10/30/2023 52
Management cont.ā€¦
ā€¢ Commence oral feeds as soon as possible
ā€¢ Enteral feed superior to parenteral
ā€¢ NGT in burns > 20% TBSA in children and > 30% TBSA in adults
ā€¢ Manage Ileus
ā€¢ Tight glucose control ā€“ esp ICU pts
ā€¢ Protein ā€“ 2g/kg body wt/day
10/30/2023 53
ā€¢ Curreri formula
ā€¢ Sutherland
ā€¢ Davies
10/30/2023 54
Management cont.ā€¦
Infection control
ā€¢ Wash down on arrival
ā€¢ Anti Tetanus prophylaxis
ā€¢ Meticulous protocol in the burn unit
ā€¢ Disciplined antibiotic use
ā€¢ Early debridement and wound closure
ā€¢ Nutrition
ā€¢ Topical antibiotic dressing
10/30/2023 55
Electrical Burn
ā€¢ Of all burns patients admitted, 3% to 5% are injured from electrical
contact.
ā€¢ Electrical current enters a part of the body, such as the fingers or
hand, and proceeds through tissues with the lowest resistance to
current, generally the nerves, blood vessels, and muscles.
ā€¢ The skin has a relatively high resistance to electrical current and is
therefore mostly spared.
ā€¢ Heat generated by the transfer of electrical current and passage of
the current itself then injures the tissues.
10/30/2023 56
Electrical Burn cont.ā€¦
ā€¢ The muscle is the major tissue through which the current flows, and
thus it sustains the most damage.
ā€¢ Injuries are divided into high- and low-voltage injuries. Threshold
being 1000v
ā€¢ Low-voltage injury is similar to thermal burns without transmission to
the deeper tissues.
10/30/2023 57
Electrical Burn cont.ā€¦
ā€¢ The syndrome of high-voltage
injury consists of varying
degrees of cutaneous burn at
the entry and exit sites,
combined with hidden
destruction of deep tissue .
ā€¢ Address Cardiac derangement.
ā€¢ The key to managing patients
with an electrical injury lies in
the treatment of the wound.
10/30/2023 58
Chemical Burns
10/30/2023 59
Management contā€¦
ā€¢ Nursing care
ā€¢ Physiotherapy
ā€¢ Psychological care
10/30/2023 60
Complications
Early
ā€¢ Hypovolemia/ Shock
ā€¢ Acute renal failure
ā€¢ Acute gastric erosion
ā€¢ Compartment syndrome
ā€¢ Gastric paralysis
ā€¢ Anemia
ā€¢ Sepsis
ā€¢ Immunocompromised
ā€¢ Severe weight loss
ā€¢ Tetanus
10/30/2023 61
Complications
Late
1. Scarring
2. Hypertrophic scars
3. Keloids
4. Contractures
5. Myositis ossificans
6. Cataracts (electric)
7. Chronic Pruritus
8. Chronic/ recurrent ulcers
9. Malignancy ā€“Marjolin's Ulcer
10/30/2023 62
Prognosis
Baux score
Expressed as % TBSA + Age
The score is a comparative indicator of burn severity, with a score over 140
considered as being un-survivable, depending on the available treatment
resources
Modified Baux score = body area affected + age of patient + 17
10/30/2023 63
.
10/30/2023 64
Prevention
According to the WHO,
ā€¢ Improve awareness
ā€¢ Develop and enforce effective policy
ā€¢ Describe burden and identify risk factors
ā€¢ Set research priorities with promotion of promising interventions
ā€¢ Provide burn prevention programs
ā€¢ Strengthen burn care
ā€¢ Strengthen capacities to carry out all of the above.
10/30/2023 65
First aid
What to do
ā€¢ Stop the burning process by removing clothing and irrigating the
burns.
ā€¢ Extinguish flames by allowing the patient to roll on the ground, or by
applying a blanket, or by using water or other fire-extinguishing
liquids.
ā€¢ Use cool running water to reduce the temperature of the burn.
ā€¢ In chemical burns, remove or dilute the chemical agent by irrigating
with large volumes of water.
ā€¢ Wrap the patient in a clean cloth or sheet and transport to the
nearest appropriate facility for medical care.
10/30/2023 66
What not to do
ā€¢ Do not start first aid before ensuring your own safety (switch off
electrical current, wear gloves for chemicals etc.)
ā€¢ Do not apply paste, oil, haldi (turmeric) or raw cotton to the burn.
ā€¢ Do not apply ice because it deepens the injury.
ā€¢ Avoid prolonged cooling with water because it will lead to
hypothermia.
ā€¢ Do not open blisters until topical antimicrobials can be applied, such
as by a health-care provider.
10/30/2023 67
ā€¢ Do not apply any material directly to the wound as it might become
infected.
ā€¢ Avoid application of topical medication until the patient has been
placed under appropriate medical care.
10/30/2023 68
Conclusion
The treatment of burns is complex and require a multidisciplinary
approach
ā€¢ Minor injuries can be treated in the community by knowledgeable
physicians.
ā€¢ Moderate and severe injuries, however, require treatment in
dedicated facilities.
ā€¢ Burn injury treatment depends on the depth and total body surface
area affected.
10/30/2023 69
Conclusion cont.ā€¦
ā€¢ Early fluid resuscitation with adequate fluids and addressing
inhalation injury saves lots of life.
ā€¢ Addressing wound comes second after initial resuscitation with
adequate covering of wound.
ā€¢ Main aim of wound care is to protect body from infection and
hypothermia.
ā€¢ Early wound excision and grafting prevents wound contracture.
ā€¢ Primary prevention- Best bet.
ā€¢ Prevent burns from occurring at all
10/30/2023 70
References
ā€¢ Burns in Nigeria: a Review A.O. Oladele and J.K. Olabanji Ann Burns
Fire Disasters. 2010 Sep 30; 23(3): 120ā€“127. Published online 2010
Sep 30.
ā€¢ Bailey & Love's Short Practice of Surgery, 27th Edition 27th Edition
ā€¢ Overview of the management of burns, Dr. Dafieware O.R
ā€¢ Https://www.Who.Int/news-room/fact-sheets/detail/burns
ā€¢ Ann burns fire disasters. 2010 sept 30; 23(3): 120ā€“127.
ā€¢ Grabb and Smith's plastic surgery seventh edition
ā€¢ Principles and practice of surgery including pathology in the tropics
4th edition
ā€¢ Principles and practice of burn care editor-in-chief sujata sarabahi
10/30/2023 71
ā€¢Thank you
10/30/2023 72

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Management of burns.pptx

  • 1. Principles of Management of Burns By Dr. Olofin K. E Registrar Casualty Dept. UATH 10/30/2023 1
  • 2. Outline ā€¢ Introduction/Definition ā€¢ Epidemiology ā€¢ Anatomy of the skin ā€¢ Pathology/Pathophysiology of burns ā€¢ Classification/wound estimation ā€¢ Management ā€¢ Complications ā€¢ Prognosis ā€¢ Prevention ā€¢ Conclusion ā€¢ References 10/30/2023 2
  • 3. Introduction/Definition Definition: Injury to living tissue arising from exposure to heat, friction, electricity, radiation, chemicals or cold ā€¢ Non-fatal burn injuries are a leading cause of morbidity. ā€¢ 2/3 of all burns happen at home ā€¢ Burn injuries continue to be a major source of mortality and morbidity in low- and middle-income countries of the world, of which Nigeria is a part. 10/30/2023 3
  • 4. Introduction ā€¢ Flame is emerging as the predominant cause of burns, and burn injury is occurring increasingly away from the domestic setting. ā€¢ The severity of the injuries is also increasing. ā€¢ Several challenges militate against optimal care for burn victims. ā€¢ Burn injuries continue to contribute significantly to the burden of disease in Nigeria. ā€¢ Avoidable complications are common and mortality remains high. 10/30/2023 4
  • 5. Epidemiology ā€¢ 4.8% of trauma deaths in Nigeria ā€¢ 6.7% of surgically related deaths. ā€¢ In children, burns and scalds are the 4th commonest cause of trauma < road traffic accidents < accidental falls < bites. ā€¢ Over 95% of fatal fire-related burns occurred in low- and middle-income countries ā€¢ Chemical burns constitute 6.3% of burns in Enugu and 5% in Ibadan ā€¢ Electrical burn injuries have an incidence of less than 1% in children and 2.8-4.6% in all burn 10/30/2023 5
  • 6. Epidemiology cont.ā€¦ ā€¢ In India, over 1 000 000 people are moderately or severely burnt every year. ā€¢ In Bangladesh, Colombia, Egypt and Pakistan, 17% of children with burns have a temporary disability and 18% have a permanent disability. ā€¢ Burns are the second most common injury in rural Nepal, accounting for 5% of disabilities. ā€¢ In 2008, over 410 000 burn injuries occurred in the United States of America, with approximately 40 000 requiring hospitalization. 10/30/2023 6
  • 7. Anatomy of the skin 10/30/2023 7 The skin: Largest organ 15% of total body weight 1.7 m2
  • 8. Essential for: ā€¢ Thermoregulation ā€¢ Prevention of fluid loss by evaporation ā€¢ Barrier against infection ā€¢ Protection from environment provided by sensory information ā€¢ Others- social etc. 10/30/2023 8
  • 9. Pathology of burns ā€¢ Fire/flames, Contact with hot liquids, hot/cold solid materials induce cellular damage via transfer of energy directly leads to coagulation necrosis. ā€¢ Chemical and electrical burns cause injury via cell membrane damage in addition to thermal injury. ā€¢ Depth of Injury depends on 3 factors 1. Causative agents 2. Temperature at which skin exposed 3. Duration of Exposure. 10/30/2023 9
  • 13. Pathophysiology Systemic Effects of Burns 1. Cardiovascular system 2. Renal system 3. Respiratory tract changes 4. Gastrointestinal tract changes 5. Central nervous system changes 6. Hematological changes 7. Metabolic changes 8. Endocrine changes 9. Immune system changes 10/30/2023 13
  • 14. Pathophysiology cont.ā€¦ Post Burn Metabolic Phenomena Two Distinct phase of metabolic changes observed in post burns. Ebb phase ā€¢ It occurs within the first 48 hours of injury ā€¢ Characterized by decrease in cardiac output, oxygen consumption and metabolic rate, as well as impaired glucose tolerance The flow phase ā€¢ These metabolic variables gradually increase within the first 5 days post injury to a plateau phase 10/30/2023 14
  • 15. Pathophysiology cont.ā€¦ Post Burn Squela ā€¢ Cardiac out put increases by 1.5 times ā€¢ Liver size increases by 225% ā€¢ Muscle protein is degraded much faster than it is synthesized. ā€¢ The net protein loss causes loss of lean body mass and severe muscle wasting. ā€¢ 10% loss ā€“ Immune Dysfunction ā€¢ 20% loss ā€“ Decrease wound healing ā€¢ 30% loss ā€“ Increased risk of Pneumonia & Pressure sores ā€¢ 40% loss ā€“ Death 10/30/2023 15
  • 17. Classifications -Depth -Types/ Source of energy - Extent Depth ā€¢ Superficial ā€¢ Partial thickness ā€¢ Superficial ā€¢ Deep ā€¢ Full thickness ā€¢ Mixed 10/30/2023 17
  • 18. Superficial burns ā€¢ old 1st degree ā€¢ Epidermis only ā€¢ Resembles Sunburn ā€¢ No blistering ā€¢ Capacity to heal completely 10/30/2023 18
  • 19. Superficial partial thickness ā€¢ Epidermal and papillary layers of dermis involved ā€¢ Blister formation ā€¢ Rupture causes weeping moist injury 10/30/2023 19
  • 20. Deep Partial Thickness ā€¢ old 2nd degree ā€¢ through epidermis, into reticular dermis ā€¢ Pale or Pink, moist, blisters, very painful ā€¢ Some capacity to heal 10/30/2023 20
  • 22. Full thickness burn ā€¢ old 3rd degree (and 4th) ā€¢ Through epidermis, dermis and connective tissue ā€¢ Appears waxy white, leathery gray or charred black and dry and is not painful ā€¢ Has various colours 10/30/2023 22
  • 24. Classification cont.ā€¦ Types/source ā€¢ Thermal: Contact, flame, Scald, ā€¢ Electrical- AC,DC ā€¢ Chemical ā€¢ Sun burn ā€¢ Lightening ā€¢ Radiation ā€¢ Laser ā€¢ Frostbite 10/30/2023 24
  • 25. Classification cont.ā€¦ Extent Assessment of extent of burn wound ā€¢ Rule of Nines: ā€¢ Quick estimate of percent of burn ā€¢ Lund and Browder: ā€¢ More accurate assessment tool ā€¢ Useful chart for children ā€“ takes into account the head size proportion. ā€¢ Rule of Palms: ā€¢ Good for estimating small patches of burn wound 10/30/2023 25
  • 28. American Burn Association Severity Classification 10/30/2023 28
  • 29. Management Prehospital care Principles 1. Ensure rescuer safety 2. Stop the burning process 3. Check for other injuries 4. Cool the burn 5. Give oxygen 6. Elevate 10/30/2023 29
  • 30. Management ATLS protocol Primary survey ā€¢ Airway: Early recognition of airway compromise, intubation. ā€¢ Breathing: Pattern of breathing. Breathing? ā€¢ Circulation: vascular access, monitor device, blood pressure. ā€¢ Disability: other injuries; fractures, abdominal injury or neurological deficit. ā€¢ Exposure: out of clothes, exposure of all orifices. ā€¢ Fluid resuscitation: 10/30/2023 30
  • 31. Management cont.ā€¦ Secondary survey Full history ā€¢ Biodata ā€¢ Cause of the burn ā€¢ Time of injury ā€¢ Place of the occurrence (closed space, presence of chemicals, noxious fumes) ā€¢ Likelihood of associated trauma (explosion,ā€¦) ā€¢ Pre-hospital interventions 10/30/2023 31
  • 32. Management cont.ā€¦ ā€¢ Detection of the mechanism of injury. ā€¢ Consideration of abuse ā€¢ Possibility of carbon monoxide intoxication Full examination ā€¢ TBSA, Burn depth, inhalational injury ā€¢ Concomitant injury, deformity, dx habitus ā€¢ Height and weight. 10/30/2023 32
  • 33. Management cont.ā€¦ Indications For admission ā€¢ Major Burns ā€¢ Special areas- face, hand, perineum, joints, inhalational ā€¢ Poly-trauma ā€¢ Co- morbidities- DM, SCD, CVA ā€¢ Domestic abuse (slightest suspicion) 10/30/2023 33
  • 34. Management cont.ā€¦ Investigations ā€¢ Electrolytes ā€¢ Blood gases ā€¢ Glucose ā€¢ Protein ā€¢ Haemoglobin (must be kept >12 g%) ā€¢ Bronchoscopy, X-rays 10/30/2023 34
  • 35. Management cont.ā€¦ Goals of management 4Rs: revive , restore, repair and rehabilitate ā€¢ Maintaining body fluids & electrolytes ā€¢ Relieving pain ā€¢ Preventing/Treating infection ā€¢ Nutrition ā€¢ Early wound cover/ healing/surgery ā€¢ Rehabilitation 10/30/2023 35
  • 36. Management cont.ā€¦ Fluid Resuscitation ā€¢ Goal- Maintain tissue perfusion ā€¢ Burns > 10% TBSA for children ā€¢ Burns > 15% TBSA for Adults ā€¢ Parkland, Brookes, Galveston, Shriners ā€¢ Crystalloids or colloids? ā€¢ Fluid monitoring ā€¢ Urine output, blood pressure ,central venous pressure, heart rate ā€¢ Urine output- 30-50ml/hr. 0.5 - 1.0 ml/kg/hr. ā€¢ Input/ output chart recorded hourly!!! 10/30/2023 36
  • 37. Management cont.ā€¦ Resuscitation Formulaā€™s ā€¢ total area FORMULA CRYSTALLOID COLLOID Parkland 4 mL/kg per % TBSA burn None None Brooke 1.5 mL/kg/% TBSA burn 0.5 mL/kg per % TBSA burn Galveston (pediatric) 5000 mL/m 2 burned area + 1500 mL/m 2 10/30/2023 37
  • 38. Management cont.ā€¦ Parklands ā€¢ Commonest ā€¢ 1/2 in first 8hrs post burn ā€¢ 1/2 in next sixteen hrs. ā€¢ Subsequently, Daily requirements plus ongoing losses after 24hrs ā€¢ Ongoing losses = 1cc/kg x TBSA ā€¢ Monitor urinary output!!! As determinant of adequate resuscitation (except in ARF) 10/30/2023 38
  • 39. Management cont.ā€¦ Pain management ā€¢ Pain- Hyperalgesia develops from exposed viable and growing nerve endings ā€¢ Pain with time becomes learned and is psychological and difficult to manage ā€¢ Pain is REAL to the patient ā€¢ IV injections not advised when burns exceeds 10% TBSA 10/30/2023 39
  • 40. Management cont.ā€¦ Analgesics- ā€¢ Opioids- morphine(adults). Pethidine , PCM ā€¢ NSAIDS- ā€¢ Oral ketamine ā€¢ Anesthesia for dressings ā€¢ Psychotherapy, encouragement ā€¢ Good dressing techniques ā€¢ Soak dressings-shower ā€¢ Products- Non Adherent, Fewer intervals ā€¢ Early mobilization 10/30/2023 40
  • 41. Management cont.ā€¦ Surgery ā€¢ Debridement ā€¢ Fasciotomy ā€¢ For compartment syndrome ā€¢ Escharoctomy ā€¢ Tangential excision + STSG ā€¢ Others as indicated 10/30/2023 41
  • 43. Management cont.ā€¦ Burn Wound dressings Principles: ā€¢ Full-thickness and deep-dermal burns need antibacterial dressings to delay colonization prior to surgery ā€¢ Superficial burns will heal and need simple dressings ā€¢ An optimal healing environment can make a difference to outcome in borderline-depth burns 10/30/2023 43
  • 44. Management cont.ā€¦ wound dressing ā€¢ Regular intervals as determined by the need (not by staffing) ā€¢ Give analgesics I.V 30 mins before procedure ( or proceed with psychotherapy) ā€¢ Layered removal of dressing ā€¢ Debride when required ā€¢ Clean with normal saline ā€¢ Dab dry ā€¢ Apply topical antibiotic ā€¢ Layered dressings applied systematically 10/30/2023 44
  • 45. Management cont.ā€¦ Dressings can be occlusive or open Benefits of occlusive dressing ā€¢ Protects against infection ā€¢ Reduces pain- nerve endings exposed to air is painful ā€¢ Providers a moist environnent for re-epithelisation ā€¢ Nursing care is easier/ not messy like open dressing ā€¢ Reduces need for frequent dressings with pain and pressure on nursing personnel 10/30/2023 45
  • 46. Management cont.ā€¦ Benefits of Open Dressings ā€¢ Easy , Quicker ā€¢ Dressing procedure less painful ā€¢ Cheaper ā€¢ Easy access to assess wounds for infection ā€¢ Great for hot tropical weather ā€¢ Difficult to move patient if extensive ā€¢ Messy on beddings ā€¢ More difficult to control hypothermia ā€¢ Requires strict control of environment, visitors 10/30/2023 46
  • 47. Management cont.ā€¦ Dressing agents Full-thickness burns and obvious deep dermal wounds Nanocrystalline silver ā€¢ Silver sulphadiazine cream: 1%broad spectrum, not painful, yellow pseudo eschar. Self limiting leucopenia ā€¢ Silver nitrate solution (0.5%) ā€¢ Mafenide asetate cream or 5% soln. Painful. Permeates eschars. Carbonic anhydrase inhibitor causes acidosis ā€¢ Cerium nitrate 10/30/2023 47
  • 48. Management cont.ā€¦ Superficial partial-thickness wounds and mixed ā€“depth wounds 1. Exposure 2. Mefix 3. mepitel 4. Hydrocolloid 5. Biobrane 6. Amniotic membrane ā€¢ Bacitracin: chlorhexidine ā€¢ Povidone iodine ā€¢ Bactroban:Mupirocin ā€“ MRSA 10/30/2023 48
  • 49. Management cont.ā€¦ Skin Substitutes ā€¢ Transcyte- cultured human fibroblasts in semi-permiable membrane on nylon matrix ā€¢ Alloderm ā€¢ Integra ā€¢ CEA ā€“ cultured epithelial autograft 10/30/2023 49
  • 50. Management cont.ā€¦ Blisters To rupture or to leave? ā€¢ Controversial ā€¢ Blister fluid contains vasoactive mediators- progression of the ischemic zone, and inhibit healing. ā€¢ The intact blister also serves as a physiologic dressing ā€¢ Blisters larger than several inches in diameter are most likely to rupture and should be removed. ā€¢ Small blisters- Can leave ā€¢ Large blister- Rupture ā€¢ Blisters over joints- Rupture 10/30/2023 50
  • 52. Management cont.ā€¦ Nutrition ā€¢ Aim- Achieve a positive nitrogen balance ā€¢ Correct deficit ā€¢ Premorbid, pre referral ā€¢ Correct on-going losses ā€¢ Chronic catabolic state ā€¢ Maintenance ā€¢ Daily requirements 10/30/2023 52
  • 53. Management cont.ā€¦ ā€¢ Commence oral feeds as soon as possible ā€¢ Enteral feed superior to parenteral ā€¢ NGT in burns > 20% TBSA in children and > 30% TBSA in adults ā€¢ Manage Ileus ā€¢ Tight glucose control ā€“ esp ICU pts ā€¢ Protein ā€“ 2g/kg body wt/day 10/30/2023 53
  • 54. ā€¢ Curreri formula ā€¢ Sutherland ā€¢ Davies 10/30/2023 54
  • 55. Management cont.ā€¦ Infection control ā€¢ Wash down on arrival ā€¢ Anti Tetanus prophylaxis ā€¢ Meticulous protocol in the burn unit ā€¢ Disciplined antibiotic use ā€¢ Early debridement and wound closure ā€¢ Nutrition ā€¢ Topical antibiotic dressing 10/30/2023 55
  • 56. Electrical Burn ā€¢ Of all burns patients admitted, 3% to 5% are injured from electrical contact. ā€¢ Electrical current enters a part of the body, such as the fingers or hand, and proceeds through tissues with the lowest resistance to current, generally the nerves, blood vessels, and muscles. ā€¢ The skin has a relatively high resistance to electrical current and is therefore mostly spared. ā€¢ Heat generated by the transfer of electrical current and passage of the current itself then injures the tissues. 10/30/2023 56
  • 57. Electrical Burn cont.ā€¦ ā€¢ The muscle is the major tissue through which the current flows, and thus it sustains the most damage. ā€¢ Injuries are divided into high- and low-voltage injuries. Threshold being 1000v ā€¢ Low-voltage injury is similar to thermal burns without transmission to the deeper tissues. 10/30/2023 57
  • 58. Electrical Burn cont.ā€¦ ā€¢ The syndrome of high-voltage injury consists of varying degrees of cutaneous burn at the entry and exit sites, combined with hidden destruction of deep tissue . ā€¢ Address Cardiac derangement. ā€¢ The key to managing patients with an electrical injury lies in the treatment of the wound. 10/30/2023 58
  • 60. Management contā€¦ ā€¢ Nursing care ā€¢ Physiotherapy ā€¢ Psychological care 10/30/2023 60
  • 61. Complications Early ā€¢ Hypovolemia/ Shock ā€¢ Acute renal failure ā€¢ Acute gastric erosion ā€¢ Compartment syndrome ā€¢ Gastric paralysis ā€¢ Anemia ā€¢ Sepsis ā€¢ Immunocompromised ā€¢ Severe weight loss ā€¢ Tetanus 10/30/2023 61
  • 62. Complications Late 1. Scarring 2. Hypertrophic scars 3. Keloids 4. Contractures 5. Myositis ossificans 6. Cataracts (electric) 7. Chronic Pruritus 8. Chronic/ recurrent ulcers 9. Malignancy ā€“Marjolin's Ulcer 10/30/2023 62
  • 63. Prognosis Baux score Expressed as % TBSA + Age The score is a comparative indicator of burn severity, with a score over 140 considered as being un-survivable, depending on the available treatment resources Modified Baux score = body area affected + age of patient + 17 10/30/2023 63 .
  • 65. Prevention According to the WHO, ā€¢ Improve awareness ā€¢ Develop and enforce effective policy ā€¢ Describe burden and identify risk factors ā€¢ Set research priorities with promotion of promising interventions ā€¢ Provide burn prevention programs ā€¢ Strengthen burn care ā€¢ Strengthen capacities to carry out all of the above. 10/30/2023 65
  • 66. First aid What to do ā€¢ Stop the burning process by removing clothing and irrigating the burns. ā€¢ Extinguish flames by allowing the patient to roll on the ground, or by applying a blanket, or by using water or other fire-extinguishing liquids. ā€¢ Use cool running water to reduce the temperature of the burn. ā€¢ In chemical burns, remove or dilute the chemical agent by irrigating with large volumes of water. ā€¢ Wrap the patient in a clean cloth or sheet and transport to the nearest appropriate facility for medical care. 10/30/2023 66
  • 67. What not to do ā€¢ Do not start first aid before ensuring your own safety (switch off electrical current, wear gloves for chemicals etc.) ā€¢ Do not apply paste, oil, haldi (turmeric) or raw cotton to the burn. ā€¢ Do not apply ice because it deepens the injury. ā€¢ Avoid prolonged cooling with water because it will lead to hypothermia. ā€¢ Do not open blisters until topical antimicrobials can be applied, such as by a health-care provider. 10/30/2023 67
  • 68. ā€¢ Do not apply any material directly to the wound as it might become infected. ā€¢ Avoid application of topical medication until the patient has been placed under appropriate medical care. 10/30/2023 68
  • 69. Conclusion The treatment of burns is complex and require a multidisciplinary approach ā€¢ Minor injuries can be treated in the community by knowledgeable physicians. ā€¢ Moderate and severe injuries, however, require treatment in dedicated facilities. ā€¢ Burn injury treatment depends on the depth and total body surface area affected. 10/30/2023 69
  • 70. Conclusion cont.ā€¦ ā€¢ Early fluid resuscitation with adequate fluids and addressing inhalation injury saves lots of life. ā€¢ Addressing wound comes second after initial resuscitation with adequate covering of wound. ā€¢ Main aim of wound care is to protect body from infection and hypothermia. ā€¢ Early wound excision and grafting prevents wound contracture. ā€¢ Primary prevention- Best bet. ā€¢ Prevent burns from occurring at all 10/30/2023 70
  • 71. References ā€¢ Burns in Nigeria: a Review A.O. Oladele and J.K. Olabanji Ann Burns Fire Disasters. 2010 Sep 30; 23(3): 120ā€“127. Published online 2010 Sep 30. ā€¢ Bailey & Love's Short Practice of Surgery, 27th Edition 27th Edition ā€¢ Overview of the management of burns, Dr. Dafieware O.R ā€¢ Https://www.Who.Int/news-room/fact-sheets/detail/burns ā€¢ Ann burns fire disasters. 2010 sept 30; 23(3): 120ā€“127. ā€¢ Grabb and Smith's plastic surgery seventh edition ā€¢ Principles and practice of surgery including pathology in the tropics 4th edition ā€¢ Principles and practice of burn care editor-in-chief sujata sarabahi 10/30/2023 71

Editor's Notes

  1. Skin divided basically into epidermis, demis and hypodermis
  2. Temp 44 degs= 6hrs to suffer irreversible burns 70ā€™ā€™= 1sec, 65 = 15secs = full thickness burns 7sec= superficial partial thickness burns
  3. 1947
  4. Severe burns covering more than 20% of the TBSA are typically followed by a period of stress, inflammation, and hypermetabolism . 1. Vasoactive mediators leucotriens bradikinins atria natriuretic peptide. 7. 12-25% of total RBC mass can be loss with 12hrs Hemolysis direct heat, massive upper GI bleeding, viscosity depressing factor 5,7 consumptive coagulopathy dic. 8. catecholamine 8. diabetes of burns 9. skin loss, damage to vascular endothelium and microcirculatory stasis
  5. 1- put off fire, switch of power. 2- Stop drop and roll. 3- ABC 4- 10mins minimum of running cold water is effective up to 1hr after burns, slows down delayed microvascular damage , provides analgesia, 5-, 6
  6. Airway ā€“ hot gases cause supraglottic airway burns and laryngeal oedema - Steam can cause subglottic burns and loss of respiratory epithelium, Smoke chemical alveolitis and respiratory failure Poisons eg CO2 Hydrogen cyanide metabolic poisoning Full thickness burns to the chest cause mechanical blockage to rib movement Airway occlusion occurs btw 4-24hrs Intubation and cricothyrodotomy if delayed
  7. From moderate burns give fluid In some parts of the world intravenous resuscitation is commenced only with burns that approach 30% TBSA
  8. Crystalloid ā€“ Ringers lactate, Nacl, hypertonic saline. Colloid ā€“ human albumin solution Maintenance for children
  9. Fasiotomy commonly for electrical burns, tangential excision dead portion of skin removed layer by layer until healthy bleeding is seen. Circumferential full-thickness burns to the limbs require emergency surgery ,incising the whole length of the injury releases its tourniquet effect Mid-axial line avoiding nerves and vessels
  10. Early debridement and grafting is the key to effective treatment of deep partial and full thickness burns in majority of cases
  11. 2. permeable wound dressing 3.Fenestrated silicone sheet
  12. Current passes the path of least resistance hence avoids the skin mostly
  13. Myocardium may be directly damaged without pacing interruption Limbs may need fasciotomies or amputation Look for and treat acidosis and myoglobinuria
  14. Damage is from corrosion and poisoning Copious lavage with water helps in most cases Then identify the chemical and assess the risk of absorption
  15. PTSD Loss of body parts