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EEG in Status
Epilepticus
By Tania Farrar
Topics
What is status epilepticus (SE)
Why do we need cEEG in SE
What is Status Epilepticus?
A seizure is a paroxysmal electrical discharge of neurons
in the brain resulting in a change of function or behaviour.
Excessive excitation and/or inadequate inhibition results
in status epilepticus.
SE can have long-term consequences depending on the
type and duration of seizures.
What is Status Epilepticus?
Clinically someone is in SE if they have a GTCS >5 minutes or multiple
shorter seizures without complete recovery to baseline in between.
GTCS lasting >30 minutes carry a risk of long term consequences due
to neuronal injury/death.
For focal SE and absence SE the duration of time to injury is
unknown.
What is Status Epilepticus?
A definition and classification of status epilepticus – Report of the ILAE Task Force on Classification of Status Epilepticus. 2015
Why do we need cEEG in SE?
1. Confirmation of SE
2. Establish cessation of electrical
seizure activity
3. Confirm burst suppression
4. Ensure we are treating seizures
Confirmation of SE
Are there ongoing Sz or are they post-ictal?
Exclusion of other pathologies
• PNES
• Movement disorders
• Drug reactions
• Encephalopathies
Establish cessation of electrical
seizure activity
Just because the physical seizure
activity has stopped does not
mean the brain is ‘quiet’
Establish cessation of electrical
seizure activity
So the muscle artefact there shows that
was a clinical seizure but what about this
next one?
Why do we need cEEG in SE?
1. Confirmation of SE
2. Establish cessation of electrical
seizure activity
3. Confirm burst suppression
4. Ensure we are treating seizures
Burst suppression
• In RSE anaesthetics are used to induce burst
suppression to try to ‘break’ the seizure
cycle.
• The ratio of burst to suppression is ~1:10
• This ratio is LESS important than the nature
of the burst
UGLY burst
PRETTY burst
Ensure we are treating seizures
1. This includes both under and over treatment
of clinical activity
2. Under treating is dangers but so is over
treating
3. Over treating can prolong sedation and
intubation.
Summary
1. SE is both a clinical and neurophysiological
diagnosis.
2. cEEG is important for managing SE as it
ensures we adequately treat electrical Sz
activity without over treating the patient.
cEEG in Status Epilepticus

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EEG and Status Eplilepticus by Tania Farrar

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  • 3. Topics What is status epilepticus (SE) Why do we need cEEG in SE
  • 4. What is Status Epilepticus? A seizure is a paroxysmal electrical discharge of neurons in the brain resulting in a change of function or behaviour. Excessive excitation and/or inadequate inhibition results in status epilepticus. SE can have long-term consequences depending on the type and duration of seizures.
  • 5. What is Status Epilepticus? Clinically someone is in SE if they have a GTCS >5 minutes or multiple shorter seizures without complete recovery to baseline in between. GTCS lasting >30 minutes carry a risk of long term consequences due to neuronal injury/death. For focal SE and absence SE the duration of time to injury is unknown.
  • 6. What is Status Epilepticus? A definition and classification of status epilepticus – Report of the ILAE Task Force on Classification of Status Epilepticus. 2015
  • 7. Why do we need cEEG in SE? 1. Confirmation of SE 2. Establish cessation of electrical seizure activity 3. Confirm burst suppression 4. Ensure we are treating seizures
  • 8. Confirmation of SE Are there ongoing Sz or are they post-ictal? Exclusion of other pathologies • PNES • Movement disorders • Drug reactions • Encephalopathies
  • 9. Establish cessation of electrical seizure activity Just because the physical seizure activity has stopped does not mean the brain is ‘quiet’
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  • 16. Establish cessation of electrical seizure activity So the muscle artefact there shows that was a clinical seizure but what about this next one?
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  • 27. Why do we need cEEG in SE? 1. Confirmation of SE 2. Establish cessation of electrical seizure activity 3. Confirm burst suppression 4. Ensure we are treating seizures
  • 28. Burst suppression • In RSE anaesthetics are used to induce burst suppression to try to ‘break’ the seizure cycle. • The ratio of burst to suppression is ~1:10 • This ratio is LESS important than the nature of the burst
  • 31. Ensure we are treating seizures 1. This includes both under and over treatment of clinical activity 2. Under treating is dangers but so is over treating 3. Over treating can prolong sedation and intubation.
  • 32. Summary 1. SE is both a clinical and neurophysiological diagnosis. 2. cEEG is important for managing SE as it ensures we adequately treat electrical Sz activity without over treating the patient.
  • 33. cEEG in Status Epilepticus

Editor's Notes

  1. including neuronal death, neuronal injury, and alteration of neuronal networks, depending on the type and duration of seizures.
  2. Exclusion of other diagnosis – PNES and movement disorders/drug reactions