saefs

1. 1
Description
Title of Invention: Sample Application 3
Technical Field
0001 The presentinventionrelatestoa coatedmedical implantcomprisingacoatinglayerdeposited
by physical vapordepositionandoptionally alsoacalciumphosphate coatinglayersuchas a
hydroxyapatitegrownonthe PVDlayer.The coatingmay be loadedwitha releasable agent
such as a pharmaceutical agent,anionor a bio molecule.

2. 2
Claims
[Claim 1] A medical implantcomprisingacoatingc h a r a c t e r i z e d in that the coating
comprisesaPVD layer,whereinthe PVDlayeriscomposedof an(Al,Me) oxideoran
amorphous(Ti,Me) oxide andsubstantiallynohydroxyapatiteisformedonthe PVD
layerwhensoakedina phosphate bufferedsalinesolutionof aboutpH7 and a
temperature below45°Cfor a periodof 1 week.
[Claim 2] The medical implantaccordingtoclaim1, whereinthe PVDlayerisanoutermost
layerof the coating.
[Claim 3] The medical implantaccordingtoclaim1 or 2, whereinMe isone or more of the
elementsSi,Cr,Hf,Zr,Ta and Nb.
[Claim 4] The medical implantaccordingtoany of the precedingclaims,whereinthe PVDlayer
iscomposedof an amorphous(Ti,Si) oxide.
[Claim 5] The medical implantaccordingtoany of claims1-3, whereinthe (Al,Me) oxideis
amorphous.
[Claim 6] The medical implantaccordingtoany of claims1-3, whereinthe (Al,Me) oxideis
crystalline.
[Claim 7] The medical implantaccordingtoclaim5 or 6, whereinthe (Al,Me) oxide comprises
one or more of the elementsTi,Si,Cr,Hf,Zr, Ta or Nb.
[Claim 8] The medical implantaccordingtoany of claims5-7, whereinthe (Al,Me) oxideisAl 2
O 3 .
[Claim 9] The medical implantaccordingtoany of the precedingclaims,whereinsaid(Al,Me)
oxide isa composite composedof atleasttwocomponentshavingdifferent
compositionand/orphase.

3. 3
Abstract
The presentinventionrelatestoa coatedmedical implantwhereinthe coatingcomprisesan
amorphousMe oxide layeroran(Al,Me) oxide layerdepositedbyphysical vapordeposition,and
whereinMe can be one or more of the elementsof Ti,Si,Cr,Hf, Zr, Ta or Nb.The PVDlayerdoesnot
have any bioactive/osseointegratingpropertiesattemperaturesbelow 45˚C.Thismakesiteasyto
remove the implantafterithasbeinginsertedinananimal orhumanbody,e.g.whenusedfor
fixatingfractures.The coatingmayfurthercomprise acalciumphosphate layer,preferablya
hydroxyapatitelayer,whichisgrownonthe PVD layerusinga biomimeticprocess.The coatingmay
be loadedwitha releasableagentsuchasa pharmaceutical agent,anionora biomolecule.The
presentinventionalsorelatestoamethodfor formingthe coatedmedical implant.

4. 4
Drawings
0002