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10. Signs & Symptoms of Hypothyroidism
Nonspecific
Specific
• Weight gain
• Fatigue
• Poor concentration
• Depression
• Diffuse muscle pain
• Menstrual irregularities
• Constipation
• Cold intolerance
• Dry skin
• Proximal muscle weakness
• Hair thinning/loss

11. Physical Exam May Reveal:
• Goiter
• Delayed deep tendon reflex
(DTR)
• Thin/brittle hair
• Dry skin
• Peripheral edema
Image from Drahreg01 on wikipedia

12. Alternate causes
of hypothyroidlike symptoms
(Gaitonde et al, 2012)
• Adrenal insufficiency (rare)
• Anemia and/or iron, b12
deficiency
• Chronic kidney disease
• Depression, anxiety disorder
• Liver disease
• Obstructive sleep apnea
• Viral infection (e.g.
mono, Lyme’s, HIV)
• Vitamin D deficiency

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17. Common Symptoms of Hyperthyroidism
• Heart palpitations
• Tachycardia/atrial
fibrillation, tremor, muscle
weakness
• Nervousness
• Sweating
• Hyperdefecation
• Heat intolerance
• Oligomenorrhea
• Weight loss despite increased
appetite
• Tired but have a hard time
sleeping
• Drooping eyelids/stare
• Exopthalamus

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