SlideShare a Scribd company logo
1 of 10
INFECTIVE ENDOCARDITIS
Goitom Gebreyesus, MD
Infective Endocarditis (IE)
o An acute or subacute inflammation of the
endocardium caused by bacteria, virus or fungi
o Common etiologic are:
Streptococcus Viridans
Staphylococcus Aureus
Group D Streptococcus
Infective …
•Pathophysiology
o Most often a complication of congenital or
Rheumatic heart disease
o But can occur with out any residual cardiac
defects
o Rheumatic heart disease, primarily mitral and
aortic valves, common in our setup
Infective …
o Preceding dental, urinary or intestinal
procedures identified in one third of patients
as a source of infection
o Other risks are central venous catheterization,
prosthetic valves etc…
o Vegetation found at the site of endocardial
erosion that result from high velocity blood
flow
Infective …
o Thus children with VSD, PDA and left sided
valvular lesions are at high risk of ID
•Clinical manifestations
o Onset can be acute and severe with:
High grade fever and prostration, or
o Insidious
With prolonged fever
o Commonly it varies within a range between the
two
Infective …
•Common symptoms are:
o Low grade fever, chills, fatigue, arthralgia,
myalgia, malaise, night sweats, weight loss,
stroke or seizure
•Physical findings:
o Tachycardia, arrhythmia
o New or changing murmur
o Splenomegaly
Infective …
o Arthritis
o Heart failure
o Neurologic deficits
o Skin manifestations such as:
Petechia, splinter hemorrhage (nail bed bleeding)
Janeway lesions (painless small hemorrhagic lesions
on palms and soles)
Osler nodes (tender pea sized intradermal nodules
in the pads of fingers)
o Clubbing
Infective …
•Lab Findings
o Blood culture
3-5 separate samples, positive in 90% of cases
without prior antibiotic intake
o Additional information can be obtained from:
Echocardiography (vegetations), raised ESR,
leucocytosis, anemia, hematuria, renal failure….
•Diagnosis
o Gold standard is blood culture
Infective…
•Treatment
o Hospitalization
o Specific
Initial empiric antibiotics to cover Gram positive
and negative organisms.
Combination of cloxaxillin, ampicillin and
gentamycin for 4-6 weeks (except gentamycin for
2 weeks)
o Supportive
For heart failure and nutrition
infective…
•Prevention
o General dental care and oral hygiene
o Treatment of infection in high risk children
o Antibiotic prophylaxis before
surgical procedures of genito-urinary and gastro-
intestinal systems

More Related Content

Similar to INFECTIVE ENDOCARDITIS.ppt

Infective Endocarditis
Infective EndocarditisInfective Endocarditis
Infective Endocarditissohailnasir
 
Infective Endocarditis
Infective EndocarditisInfective Endocarditis
Infective EndocarditisDiya Saleh
 
Infective endocarditis/ endocarditis
Infective endocarditis/ endocarditisInfective endocarditis/ endocarditis
Infective endocarditis/ endocarditisSundaresanL
 
Infective endocarditis 2020
Infective endocarditis 2020Infective endocarditis 2020
Infective endocarditis 2020Nitin Das
 
heart_disease.ppt
heart_disease.pptheart_disease.ppt
heart_disease.pptesicOrtho1
 
Rheumatic heart disease
Rheumatic heart diseaseRheumatic heart disease
Rheumatic heart diseaseGeorge Kariuki
 
Infective endocarditis
Infective endocarditisInfective endocarditis
Infective endocarditissanafarooq234
 
Lecture no.3 myo peri-carditis,rf.ie CVS
Lecture no.3 myo peri-carditis,rf.ie CVSLecture no.3 myo peri-carditis,rf.ie CVS
Lecture no.3 myo peri-carditis,rf.ie CVSbharat kumar
 
Myocarditis pediatrics ppt
Myocarditis pediatrics pptMyocarditis pediatrics ppt
Myocarditis pediatrics pptRajPatel822
 
Infective Endocarditis & Noninfected vagetation presentation
Infective Endocarditis & Noninfected vagetation presentation Infective Endocarditis & Noninfected vagetation presentation
Infective Endocarditis & Noninfected vagetation presentation Tahir Ramzan
 
Myocarditis & Pericarditis Diagnosis and Management
Myocarditis & Pericarditis Diagnosis and ManagementMyocarditis & Pericarditis Diagnosis and Management
Myocarditis & Pericarditis Diagnosis and Managementfarah al souheil
 

Similar to INFECTIVE ENDOCARDITIS.ppt (20)

Infective Endocarditis
Infective EndocarditisInfective Endocarditis
Infective Endocarditis
 
ACQUIRED.pptx
ACQUIRED.pptxACQUIRED.pptx
ACQUIRED.pptx
 
Endocarditis
EndocarditisEndocarditis
Endocarditis
 
Infective Endocarditis
Infective EndocarditisInfective Endocarditis
Infective Endocarditis
 
Endocarditis
Endocarditis Endocarditis
Endocarditis
 
Infective endocarditis/ endocarditis
Infective endocarditis/ endocarditisInfective endocarditis/ endocarditis
Infective endocarditis/ endocarditis
 
Infective endocarditis 2020
Infective endocarditis 2020Infective endocarditis 2020
Infective endocarditis 2020
 
heart_disease.ppt
heart_disease.pptheart_disease.ppt
heart_disease.ppt
 
ARF DEV (1).pptx
ARF DEV (1).pptxARF DEV (1).pptx
ARF DEV (1).pptx
 
A Case of Infective Endocarditis
A Case of Infective EndocarditisA Case of Infective Endocarditis
A Case of Infective Endocarditis
 
Rheumatic heart disease
Rheumatic heart diseaseRheumatic heart disease
Rheumatic heart disease
 
Infective endocarditis
Infective endocarditisInfective endocarditis
Infective endocarditis
 
Lecture no.3 myo peri-carditis,rf.ie CVS
Lecture no.3 myo peri-carditis,rf.ie CVSLecture no.3 myo peri-carditis,rf.ie CVS
Lecture no.3 myo peri-carditis,rf.ie CVS
 
Myocarditis pediatrics ppt
Myocarditis pediatrics pptMyocarditis pediatrics ppt
Myocarditis pediatrics ppt
 
ppt of endocarditis.pptx
ppt of endocarditis.pptxppt of endocarditis.pptx
ppt of endocarditis.pptx
 
Congenital heart diseases
Congenital heart diseasesCongenital heart diseases
Congenital heart diseases
 
Infective Endocarditis & Noninfected vagetation presentation
Infective Endocarditis & Noninfected vagetation presentation Infective Endocarditis & Noninfected vagetation presentation
Infective Endocarditis & Noninfected vagetation presentation
 
Myocarditis & Pericarditis Diagnosis and Management
Myocarditis & Pericarditis Diagnosis and ManagementMyocarditis & Pericarditis Diagnosis and Management
Myocarditis & Pericarditis Diagnosis and Management
 
Infective endocarditis ESC guidelines Ahmed Yehia. MD
Infective endocarditis ESC guidelines Ahmed Yehia. MDInfective endocarditis ESC guidelines Ahmed Yehia. MD
Infective endocarditis ESC guidelines Ahmed Yehia. MD
 
thrombo done1.ppt
thrombo done1.pptthrombo done1.ppt
thrombo done1.ppt
 

More from mergawekwaya

cholecystitis-cholelithiasis-presentation.ppt
cholecystitis-cholelithiasis-presentation.pptcholecystitis-cholelithiasis-presentation.ppt
cholecystitis-cholelithiasis-presentation.pptmergawekwaya
 
7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptx7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptxmergawekwaya
 
7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptx7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptxmergawekwaya
 
4.1 case-control and cohort.pdf
4.1 case-control and cohort.pdf4.1 case-control and cohort.pdf
4.1 case-control and cohort.pdfmergawekwaya
 
4 Epidemiological Study Designs 1.pdf
4 Epidemiological Study Designs 1.pdf4 Epidemiological Study Designs 1.pdf
4 Epidemiological Study Designs 1.pdfmergawekwaya
 
Epidata application.pptx
Epidata application.pptxEpidata application.pptx
Epidata application.pptxmergawekwaya
 
Cardiovascular Diseases.ppt
Cardiovascular Diseases.pptCardiovascular Diseases.ppt
Cardiovascular Diseases.pptmergawekwaya
 
pancytopenia-170119201048.pdf
pancytopenia-170119201048.pdfpancytopenia-170119201048.pdf
pancytopenia-170119201048.pdfmergawekwaya
 
Thyroid Disorder.pptx
Thyroid Disorder.pptxThyroid Disorder.pptx
Thyroid Disorder.pptxmergawekwaya
 
thromboticdisorders-150818135124-lva1-app6892.pdf
thromboticdisorders-150818135124-lva1-app6892.pdfthromboticdisorders-150818135124-lva1-app6892.pdf
thromboticdisorders-150818135124-lva1-app6892.pdfmergawekwaya
 
myasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.ppt
myasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.pptmyasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.ppt
myasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.pptmergawekwaya
 
M43cmyastheniagravisnursinginterventions (1).ppt
M43cmyastheniagravisnursinginterventions (1).pptM43cmyastheniagravisnursinginterventions (1).ppt
M43cmyastheniagravisnursinginterventions (1).pptmergawekwaya
 
Myasthenia Gravis.ppt
Myasthenia Gravis.pptMyasthenia Gravis.ppt
Myasthenia Gravis.pptmergawekwaya
 
Chapter 1- MSC PKs & PDs -Ok11.pdf
Chapter 1- MSC PKs & PDs -Ok11.pdfChapter 1- MSC PKs & PDs -Ok11.pdf
Chapter 1- MSC PKs & PDs -Ok11.pdfmergawekwaya
 

More from mergawekwaya (18)

cholecystitis-cholelithiasis-presentation.ppt
cholecystitis-cholelithiasis-presentation.pptcholecystitis-cholelithiasis-presentation.ppt
cholecystitis-cholelithiasis-presentation.ppt
 
7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptx7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptx
 
7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptx7 Lecture 8 Outbrek invesitgation.pptx
7 Lecture 8 Outbrek invesitgation.pptx
 
4.1 case-control and cohort.pdf
4.1 case-control and cohort.pdf4.1 case-control and cohort.pdf
4.1 case-control and cohort.pdf
 
4 Epidemiological Study Designs 1.pdf
4 Epidemiological Study Designs 1.pdf4 Epidemiological Study Designs 1.pdf
4 Epidemiological Study Designs 1.pdf
 
Epidata application.pptx
Epidata application.pptxEpidata application.pptx
Epidata application.pptx
 
Covid1.ppt
Covid1.pptCovid1.ppt
Covid1.ppt
 
epilepsy
epilepsy epilepsy
epilepsy
 
Cardiovascular Diseases.ppt
Cardiovascular Diseases.pptCardiovascular Diseases.ppt
Cardiovascular Diseases.ppt
 
Edocrinee.pptx
Edocrinee.pptxEdocrinee.pptx
Edocrinee.pptx
 
pancytopenia-170119201048.pdf
pancytopenia-170119201048.pdfpancytopenia-170119201048.pdf
pancytopenia-170119201048.pdf
 
dka.ppt
dka.pptdka.ppt
dka.ppt
 
Thyroid Disorder.pptx
Thyroid Disorder.pptxThyroid Disorder.pptx
Thyroid Disorder.pptx
 
thromboticdisorders-150818135124-lva1-app6892.pdf
thromboticdisorders-150818135124-lva1-app6892.pdfthromboticdisorders-150818135124-lva1-app6892.pdf
thromboticdisorders-150818135124-lva1-app6892.pdf
 
myasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.ppt
myasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.pptmyasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.ppt
myasthenia_gravis_carpal_tunnel_gbs_mnd_cord_compression_ms_stroke.ppt
 
M43cmyastheniagravisnursinginterventions (1).ppt
M43cmyastheniagravisnursinginterventions (1).pptM43cmyastheniagravisnursinginterventions (1).ppt
M43cmyastheniagravisnursinginterventions (1).ppt
 
Myasthenia Gravis.ppt
Myasthenia Gravis.pptMyasthenia Gravis.ppt
Myasthenia Gravis.ppt
 
Chapter 1- MSC PKs & PDs -Ok11.pdf
Chapter 1- MSC PKs & PDs -Ok11.pdfChapter 1- MSC PKs & PDs -Ok11.pdf
Chapter 1- MSC PKs & PDs -Ok11.pdf
 

Recently uploaded

POST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptxPOST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptxvirengeeta
 
Presentation on Parasympathetic Nervous System
Presentation on Parasympathetic Nervous SystemPresentation on Parasympathetic Nervous System
Presentation on Parasympathetic Nervous SystemPrerana Jadhav
 
See the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformSee the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformKweku Zurek
 
Case Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptxCase Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptxNiranjan Chavan
 
Pharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingPharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingArunagarwal328757
 
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
Glomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptxGlomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptxDr.Nusrat Tariq
 
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptxCOVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptxBibekananda shah
 
Report Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptxReport Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptxbkling
 
Culture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptxCulture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptxDr. Dheeraj Kumar
 
The next social challenge to public health: the information environment.pptx
The next social challenge to public health:  the information environment.pptxThe next social challenge to public health:  the information environment.pptx
The next social challenge to public health: the information environment.pptxTina Purnat
 
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptxSYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptxdrashraf369
 
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...sdateam0
 
Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.Prerana Jadhav
 
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.ANJALI
 
call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in munirka  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
Primary headache and facial pain. (2024)
Primary headache and facial pain. (2024)Primary headache and facial pain. (2024)
Primary headache and facial pain. (2024)Mohamed Rizk Khodair
 
PERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptx
PERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptxPERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptx
PERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptxdrashraf369
 

Recently uploaded (20)

POST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptxPOST NATAL EXERCISES AND ITS IMPACT.pptx
POST NATAL EXERCISES AND ITS IMPACT.pptx
 
Presentation on Parasympathetic Nervous System
Presentation on Parasympathetic Nervous SystemPresentation on Parasympathetic Nervous System
Presentation on Parasympathetic Nervous System
 
See the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy PlatformSee the 2,456 pharmacies on the National E-Pharmacy Platform
See the 2,456 pharmacies on the National E-Pharmacy Platform
 
Case Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptxCase Report Peripartum Cardiomyopathy.pptx
Case Report Peripartum Cardiomyopathy.pptx
 
Pharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingPharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, Pricing
 
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
Glomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptxGlomerular Filtration rate and its determinants.pptx
Glomerular Filtration rate and its determinants.pptx
 
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
COVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptxCOVID-19  (NOVEL CORONA  VIRUS DISEASE PANDEMIC ).pptx
COVID-19 (NOVEL CORONA VIRUS DISEASE PANDEMIC ).pptx
 
Report Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptxReport Back from SGO: What’s New in Uterine Cancer?.pptx
Report Back from SGO: What’s New in Uterine Cancer?.pptx
 
Culture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptxCulture and Health Disorders Social change.pptx
Culture and Health Disorders Social change.pptx
 
The next social challenge to public health: the information environment.pptx
The next social challenge to public health:  the information environment.pptxThe next social challenge to public health:  the information environment.pptx
The next social challenge to public health: the information environment.pptx
 
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptxSYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
SYNDESMOTIC INJURY- ANATOMICAL REPAIR.pptx
 
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...Big Data Analysis Suggests COVID  Vaccination Increases Excess Mortality Of  ...
Big Data Analysis Suggests COVID Vaccination Increases Excess Mortality Of ...
 
Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.Presentation on General Anesthetics pdf.
Presentation on General Anesthetics pdf.
 
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in paharganj DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.Statistical modeling in pharmaceutical research and development.
Statistical modeling in pharmaceutical research and development.
 
call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in aerocity DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in munirka  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in munirka DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
Primary headache and facial pain. (2024)
Primary headache and facial pain. (2024)Primary headache and facial pain. (2024)
Primary headache and facial pain. (2024)
 
PERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptx
PERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptxPERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptx
PERFECT BUT PAINFUL TKR -ROLE OF SYNOVECTOMY.pptx
 

INFECTIVE ENDOCARDITIS.ppt

  • 2. Infective Endocarditis (IE) o An acute or subacute inflammation of the endocardium caused by bacteria, virus or fungi o Common etiologic are: Streptococcus Viridans Staphylococcus Aureus Group D Streptococcus
  • 3. Infective … •Pathophysiology o Most often a complication of congenital or Rheumatic heart disease o But can occur with out any residual cardiac defects o Rheumatic heart disease, primarily mitral and aortic valves, common in our setup
  • 4. Infective … o Preceding dental, urinary or intestinal procedures identified in one third of patients as a source of infection o Other risks are central venous catheterization, prosthetic valves etc… o Vegetation found at the site of endocardial erosion that result from high velocity blood flow
  • 5. Infective … o Thus children with VSD, PDA and left sided valvular lesions are at high risk of ID •Clinical manifestations o Onset can be acute and severe with: High grade fever and prostration, or o Insidious With prolonged fever o Commonly it varies within a range between the two
  • 6. Infective … •Common symptoms are: o Low grade fever, chills, fatigue, arthralgia, myalgia, malaise, night sweats, weight loss, stroke or seizure •Physical findings: o Tachycardia, arrhythmia o New or changing murmur o Splenomegaly
  • 7. Infective … o Arthritis o Heart failure o Neurologic deficits o Skin manifestations such as: Petechia, splinter hemorrhage (nail bed bleeding) Janeway lesions (painless small hemorrhagic lesions on palms and soles) Osler nodes (tender pea sized intradermal nodules in the pads of fingers) o Clubbing
  • 8. Infective … •Lab Findings o Blood culture 3-5 separate samples, positive in 90% of cases without prior antibiotic intake o Additional information can be obtained from: Echocardiography (vegetations), raised ESR, leucocytosis, anemia, hematuria, renal failure…. •Diagnosis o Gold standard is blood culture
  • 9. Infective… •Treatment o Hospitalization o Specific Initial empiric antibiotics to cover Gram positive and negative organisms. Combination of cloxaxillin, ampicillin and gentamycin for 4-6 weeks (except gentamycin for 2 weeks) o Supportive For heart failure and nutrition
  • 10. infective… •Prevention o General dental care and oral hygiene o Treatment of infection in high risk children o Antibiotic prophylaxis before surgical procedures of genito-urinary and gastro- intestinal systems