7. Renal diseases associated with major types of liver disease Membranous glomerulonephritis (GN), membranoproliferative GN, IgA nephropathy, focal segmental glomerulosclerosis Hepatitis B Membranoproliferative GN, membranous GN, cryoglobulinemia, fibrillary GN, IgA nephropathy, tubulointerstitial nephritis Hepatitis C IgA nephropathy Alcoholic liver disease Prerenal azotemia/acute tubular necrosis from hypovolemia, decreased cardiac output, sepsis; acute tubular necrosis Obstructive jaundice Membranous GN, antineutrophil cytoplasmic autoantibody-positive vasculitis, antiglomerular basement membrane disease, renal tubular acidosis, tubulointerstitial nephritis Primary biliary cirrhosis Membranous GN, membranoproliferative GN, antineutrophil cytoplasmic autoantibody-positive vasculitis Primary sclerosing cholangitis Renal tubular acidosis (Type 1) secondary to copper deposition Wilson’s disease Membranoproliferative GN, antiglomerular basement membrane disease Alpha-1 antitrypsin deficiency

8. Systemic diseases involving both liver and kidney Acetaminophen, ASA Drug toxicity Sarcoidosis Granulomatous diseases Malaria Infectious diseases Amyloidosis Infiltrative diseases Lupus Inflammatory Non alcoholic fatty liver disease Pre-eclapmsia/HELLP Hmeloysis, elevated liver enzymes, low platelets Autosomal dominant Polycystic kidney/liver disease Sickle cell disease Congestive heart failure, sepsis, hypovolemia Shock states

11. Acute kidney injury network(AKIN)acute kidney injury staging criteria

13. Bacterial infection Large volume paracentesis GIt bleeding Acute alcoholic hepatitis Renal vasoconstriction Cardiac dysfunction ( (septic or cirrhotic Worsening hyperdynamic circulation Renal Vasoconstrictor ↑ Renal Vasodilator ↓

15. ` Summary of studies evaluating the role of novel blood and urine kidney injury biomarkers

26. Staging criteria for chronic kidney disease

36. THANK YOU