Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...
10.1111-pcmr.13038Figure130380001.pptx
1. A Focused review on the pathophysiology of post‐inflammatory hyperpigmentation
Pigment Cell Melanoma Res, Volume: 35, Issue: 3, Pages: 320-327, First published: 20 March 2022, DOI: (10.1111/pcmr.13038)
Editor's Notes
Diagram illustrating the proposed mechanism by which post‐inflammatory hyperpigmentation (PIH) occurs. In this illustration, the major (proposed) pathways involved in PIH include the release of inflammatory cytokines from keratinocytes and growth factors from dermal fibroblasts. Following the production of melanin, its deposition in the dermis can occur in two ways, which are illustrated in this diagram: (1) Melanin can directly be deposited into the dermis through the gaps in basal lamina; (2) macrophages engulf melanin in the epidermis; these melanophages migrate from the epidermis to the dermis, which contribute to dermal pigmentation
IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON PERMISSIONS@WILEY.COM OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER.