Summary of heart disease and HIV

1. JG Hakim
University of Zimbabwe Clinical Research Centre
Harare
Zimbabwe

2. Heart Disease in HIV Infection
 Myocardium
 Cardiomyopathy or HIV associated Heart Disease
 Conduction abnormalities
 ? Impact on coronary artery disease
 Endocardium
 Endocarditis-infective, but also non-infective
 Pericardium
 Non-infective
 Infective-TB
 Vascular Disease
 Aneurysms

3. Interest
 Pericardial Disease
 Role of adjunctive steroids
 Mortality
 Morbidity
 Quality of life
 Constrictive pericarditis
 HIV associated Cardiomyopathy
 Presentation
 Prognosis

4. Heart Disease and HIV infection
 Medical
 Does HIV infection modify manifestations, presentation
and approach to heart disease?
 HAART and heart disease
 AZT-cardiotoxicity
 ATV-heart block
 PIs & other ARVs- dyslipedemia, insulin resistance, Diabetes
mellitus-risk factors for CAD
 WHO Staging
 Extra-pulmonary TB-stage IV
 Toxoplasmosis-stage IV
 HIV associated Cardiomyopathy-stage IV

5. Heart Disease and HIV infection
 Surgical
 Cardiac
 Valvular heart disease
 Coronary artery disease
 Other
 Non-cardiac
 Precautions for surgery and anaesthesia