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#ENZIAN
Classification of peritoneal, ovarian and deep endometriosis
TEILNEHMER AG #ENZIAN KLASSIFIZIERUNG
➤ Jörg Keckstein
➤ Laurin Burla
➤ Barbara Brandmayr
➤ Rüdiger Müller
➤ Sigrid Keckstein
➤ Raul Donutiu
➤ Eliana Montanari
➤ Valentin Menke
➤ Olav Fehres
➤ Mohammad Aslam Khan
➤ Andrea Noppe
➤ Maciej Mierzwinski
➤ Elvin Piriyev
#ENZIAN
UPDATED #ENZIAN- CLASSIFICATION
PERITONEAL ENDOMETRIOSIS = P
1.Virtual area of the circle in which all
lesions fit in
2.Diameter of circle (cm)
3.Number of foci is not respected
4.USD and MRI not to be used for P
5.All superficial lesions , <5 mm (visceral and
parietal peritoneum)
cm
P 1 <3
P2 3-7
P 3 >7
UPDATED #ENZIAN- CLASSIFICATION
OVARIAN-ENDOMETRIOSIS = O
➤ Sum of maximal diameters of all
endometriotic lesions
➤ left und right separately annotated (l /r ).
➤ Superficial peritoneal lesions (P) on the
ovarian surface are not respected
➤ m ovary missing
➤ x unknown/ not visible
➤ Ultrasound: use IOTA criteria, maximal
diameter in cm
Diameter (cm) l / r
O1 < 3 /
O 2 3-7 /
O3 >7 /
UPDATED #ENZIAN- CLASSIFICATION
ADHESIONS - TUBOOVARIAN UNIT
➤ Classify left (l) and right (r) seperately
➤ Criteria for classification are:
➤ adhesions,
➤ Patency test
➤ m tube is missing
➤ x unknown/not visible
➤ + or - Patency test: pos. or neg.
T Descriptive l / r
T1
mild,
tuboovarian unit adhesive to
pelvic sidewall
/
T 2
moderate
T1 and adhesive to uterus
/
T 3
severe
T2 and adhesive to bowel /USL
/
ENZIAN Klassifikation (2002, 2012)
Classification
UPDATED #ENZIAN- CLASSIFICATION
A COMPARTMENT
(VAGINA, RECTOVAGINAL SEPTUM - RVS)
➤ Maximal diameter (cm) measured in
sagittal, i.e. midline section
➤ Ultrasound: use IDEA definition of
vagina and RVS
Length (cm)
A1 < 1
A 2 1-3
A3 >3
Enzian A2
UPDATED #ENZIAN- CLASSIFICATION
B COMPARTMENT
(UTEROSACRAL/ CARDINAL LIGAMENTS, PELVIC SIDEWALL)
➤ Maximal diameter , measured in lateral/
laterodorsal direction
➤ Annotation of the left (l)and right(r)
side is separated by a slash ( / )
➤ Ultrasound: oblique section
Length (cm) l / r
B1 < 1 /
B 2 1-3 /
B3 >3 /
UPDATED #ENZIAN- CLASSIFICATION
C COMPARTMENT (RECTUM)
➤ Maximal diameter (cm) of the
lesion in sagittal section
➤ Lesion infiltrates muscularis
➤ Ultrasound: use IDEA definition
for rectum and longitudinal
measurement of rectal DE
Lenght (cm)
C1 ≤ 1
C 2 1-3
C3 >3
r-ASRM 1 — Enzian B3/0,C3
Enzian C3
> 3cm
UPDATED #ENZIAN- CLASSIFICATION
URETER ENDOMETRIOSIS = FU
➤ Side l (left) /(right)
➤ Ultrasound: Dilatation of ureter > 8mm
UPDATED #ENZIAN- CLASSIFICATION
OTHER BOWEL ENDOMETRIOSIS = FI (SIGMA, APPENDIX, ....)
➤ Previously - FI.
➤ Describes bowel endometriosis (>16 cm distance
from the anal verge) excluding rectum
➤ The affected organ will added in parentheses
UPDATED #ENZIAN- CLASSIFICATION
ADENOMYOSIS = FA
➤ Only given in case of clinically high-grade
suspicion of adenomyosis.
➤ Describes adenomyosis pre- or intraoperatively
and / or histologically
➤ Ultrasound : use MUSA criteria
➤
• FA = adenomyosis;
o Surgical findings which are obvious for adenomyosis (appearance, consistency, size)
o Histologic diagnosis
o Ultrasound signs
Ultrasound : Adenomyosis will be assessed sonographically using the Morphological Uterus Sonographic
Assessment (MUSA) (17) criteria . But the classificaEon does not respect the various appearance of
adenomyosis in detail.
➤
FA
C3
Enzian C3, FA
UPDATED #ENZIAN- CLASSIFICATION
F (…) OTHER EXTRAGENITAL LOCALISATION
➤ Instead of previously O for "other" in brackets cite the localization
directly
➤ Example: F(umbilicus) or F(diaphragm right)
or F (plexus sacralis, right)
➤ Individual compartments are written with large letters in an order
➤ P ,O( / ),A , B( / ), C ,F ( )……
➤ The individual stages (numbers) according to the specification are written directly
after the letter.
Number 0 in case of no involvement.
There is a comma between each individual compartment.
➤ Paired organs (Ovary, Tube, B (USL, parametrium),) are annotated accordingly to the
side.
A slash separates left /right ( / ).
➤ All F lesions are only written in case if they are involved
➤ F(..) such as abdominal wall, diaphragma, nerve e.g.. are written in brackets.
➤ The spelling of the annotation
➤ Example :
➤ Superficial endometriosis on the peritoneum (P)< 3cm in sum = P1
➤ No ovarian (O) endometriosis = O0/0
➤ No adhesions = T0/0
➤ No lesion in the A compartment = A0
➤ Deep Endometriosis (B) left USL < 1cm, right USL 1-3cm, = B1/2
➤ Hydroureter right(FU) = FUright
➤ Endometriosis in the appendix (FI) = FI(App.)
Annota3on of only the affected compartments and organs:
or
Annota3on of all organs and compartments
#Enzian P1, B1/2, FU(right), FI(Appendix)
#Enzian P1, O0/0, T0/0, A0, B1/2, C0, FU(right), FI(Appendix)
#Enzian P2, O2/1, T3/3, A3, B2/3, C3, FU(r)

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ENZIAN-Endometriosis

  • 1. #ENZIAN Classification of peritoneal, ovarian and deep endometriosis
  • 2. TEILNEHMER AG #ENZIAN KLASSIFIZIERUNG ➤ Jörg Keckstein ➤ Laurin Burla ➤ Barbara Brandmayr ➤ Rüdiger Müller ➤ Sigrid Keckstein ➤ Raul Donutiu ➤ Eliana Montanari ➤ Valentin Menke ➤ Olav Fehres ➤ Mohammad Aslam Khan ➤ Andrea Noppe ➤ Maciej Mierzwinski ➤ Elvin Piriyev
  • 3.
  • 5. UPDATED #ENZIAN- CLASSIFICATION PERITONEAL ENDOMETRIOSIS = P 1.Virtual area of the circle in which all lesions fit in 2.Diameter of circle (cm) 3.Number of foci is not respected 4.USD and MRI not to be used for P 5.All superficial lesions , <5 mm (visceral and parietal peritoneum) cm P 1 <3 P2 3-7 P 3 >7
  • 6. UPDATED #ENZIAN- CLASSIFICATION OVARIAN-ENDOMETRIOSIS = O ➤ Sum of maximal diameters of all endometriotic lesions ➤ left und right separately annotated (l /r ). ➤ Superficial peritoneal lesions (P) on the ovarian surface are not respected ➤ m ovary missing ➤ x unknown/ not visible ➤ Ultrasound: use IOTA criteria, maximal diameter in cm Diameter (cm) l / r O1 < 3 / O 2 3-7 / O3 >7 /
  • 7. UPDATED #ENZIAN- CLASSIFICATION ADHESIONS - TUBOOVARIAN UNIT ➤ Classify left (l) and right (r) seperately ➤ Criteria for classification are: ➤ adhesions, ➤ Patency test ➤ m tube is missing ➤ x unknown/not visible ➤ + or - Patency test: pos. or neg. T Descriptive l / r T1 mild, tuboovarian unit adhesive to pelvic sidewall / T 2 moderate T1 and adhesive to uterus / T 3 severe T2 and adhesive to bowel /USL /
  • 8. ENZIAN Klassifikation (2002, 2012) Classification
  • 9. UPDATED #ENZIAN- CLASSIFICATION A COMPARTMENT (VAGINA, RECTOVAGINAL SEPTUM - RVS) ➤ Maximal diameter (cm) measured in sagittal, i.e. midline section ➤ Ultrasound: use IDEA definition of vagina and RVS Length (cm) A1 < 1 A 2 1-3 A3 >3
  • 11. UPDATED #ENZIAN- CLASSIFICATION B COMPARTMENT (UTEROSACRAL/ CARDINAL LIGAMENTS, PELVIC SIDEWALL) ➤ Maximal diameter , measured in lateral/ laterodorsal direction ➤ Annotation of the left (l)and right(r) side is separated by a slash ( / ) ➤ Ultrasound: oblique section Length (cm) l / r B1 < 1 / B 2 1-3 / B3 >3 /
  • 12.
  • 13.
  • 14.
  • 15.
  • 16. UPDATED #ENZIAN- CLASSIFICATION C COMPARTMENT (RECTUM) ➤ Maximal diameter (cm) of the lesion in sagittal section ➤ Lesion infiltrates muscularis ➤ Ultrasound: use IDEA definition for rectum and longitudinal measurement of rectal DE Lenght (cm) C1 ≤ 1 C 2 1-3 C3 >3
  • 17. r-ASRM 1 — Enzian B3/0,C3
  • 19. UPDATED #ENZIAN- CLASSIFICATION URETER ENDOMETRIOSIS = FU ➤ Side l (left) /(right) ➤ Ultrasound: Dilatation of ureter > 8mm
  • 20. UPDATED #ENZIAN- CLASSIFICATION OTHER BOWEL ENDOMETRIOSIS = FI (SIGMA, APPENDIX, ....) ➤ Previously - FI. ➤ Describes bowel endometriosis (>16 cm distance from the anal verge) excluding rectum ➤ The affected organ will added in parentheses
  • 21. UPDATED #ENZIAN- CLASSIFICATION ADENOMYOSIS = FA ➤ Only given in case of clinically high-grade suspicion of adenomyosis. ➤ Describes adenomyosis pre- or intraoperatively and / or histologically ➤ Ultrasound : use MUSA criteria ➤ • FA = adenomyosis; o Surgical findings which are obvious for adenomyosis (appearance, consistency, size) o Histologic diagnosis o Ultrasound signs Ultrasound : Adenomyosis will be assessed sonographically using the Morphological Uterus Sonographic Assessment (MUSA) (17) criteria . But the classificaEon does not respect the various appearance of adenomyosis in detail. ➤
  • 23. UPDATED #ENZIAN- CLASSIFICATION F (…) OTHER EXTRAGENITAL LOCALISATION ➤ Instead of previously O for "other" in brackets cite the localization directly ➤ Example: F(umbilicus) or F(diaphragm right) or F (plexus sacralis, right)
  • 24. ➤ Individual compartments are written with large letters in an order ➤ P ,O( / ),A , B( / ), C ,F ( )…… ➤ The individual stages (numbers) according to the specification are written directly after the letter. Number 0 in case of no involvement. There is a comma between each individual compartment. ➤ Paired organs (Ovary, Tube, B (USL, parametrium),) are annotated accordingly to the side. A slash separates left /right ( / ). ➤ All F lesions are only written in case if they are involved ➤ F(..) such as abdominal wall, diaphragma, nerve e.g.. are written in brackets. ➤ The spelling of the annotation
  • 25. ➤ Example : ➤ Superficial endometriosis on the peritoneum (P)< 3cm in sum = P1 ➤ No ovarian (O) endometriosis = O0/0 ➤ No adhesions = T0/0 ➤ No lesion in the A compartment = A0 ➤ Deep Endometriosis (B) left USL < 1cm, right USL 1-3cm, = B1/2 ➤ Hydroureter right(FU) = FUright ➤ Endometriosis in the appendix (FI) = FI(App.)
  • 26. Annota3on of only the affected compartments and organs: or Annota3on of all organs and compartments #Enzian P1, B1/2, FU(right), FI(Appendix) #Enzian P1, O0/0, T0/0, A0, B1/2, C0, FU(right), FI(Appendix)
  • 27. #Enzian P2, O2/1, T3/3, A3, B2/3, C3, FU(r)