Wim Smit, Future Diagnostics, Health Valley Event 2010

1. 17 maart 2010 by WimSmit 12-03-2010 1 In Vitro Diagnostiek “Bloedserieus”

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3. 12-03-2010 3 About us!

4. Mission Future Diagnostics strives to become the best developer of high-quality and innovative diagnostic tests, today, and in the future seen in the eyes of our customers and our employees.

5. Vision Future Diagnostics strives to become the market leader in test development for third parties. We want to become the independent partner of the top 25 IVD companies for their test development. We would like to achieve this position by translating new technologies and novel ‘Intellectual Properties’ to the development of innovative tests with the shortest possible development time at the lowest possible costs.

6. Facts Activities started May 01st, 1997 Privately owned company, MBO completed Oct 5th, 2007 6 employees in1997 / current number of employees is 60 Current number of projects is 34 / 40 available slots 19 Scientists with University degree 2 facilities: Nieuweweg and Edisonstraat Received ISO-9001/EN46001 certification Oct 97 Received ISO 9001/2000 and ISO 13485 Oct 2003 In compliance with the In Vitro Diagnostics Directive(IVDD) and the FDA’s Quality System Regulation (QSR) for medical devices 12-03-2010 6

7. Our Facilities 12-03-2010 7

8. 12-03-2010 8 Assays for > different analytes!

9. Assays for > different analytes! 12-03-2010 9

10. 12-03-2010 10 Assays for > different analytes!

11. 12-03-2010 11 Customers Confidential

12. 12-03-2010 12 Customers

13. 12-03-2010 13 Experience on automated platforms

14. 12-03-2010 14 Area’s of major interest Development of diagnostic tests on different automated platforms. Prototyping of POC tests for diagnoses in the areas of surgery, transplantation, stroke, minor and severe head injury. Research on new, innovative and sensitive technologies in the area of “near to patient testing”.

15. 12-03-2010 15 Trends, Opportunities & Threats in the Healthcare! Source: TriMark Publications

16. Trends in healthcare Less than 5% of the $3 trillion spent each year on the health care worldwide is for clinical laboratory services. Considering that nearly 70% of health care decisions are based on critical diagnostics information, biomedical testing represents a significant source of value in healthcare. Source: TriMark Publications

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19. Reducing healthcare costs by increasing use IVD tests.

20. Technological development, new tests and markers

21. Point of Care testing outside the laboratory directly to the patient, ambulance, first aid or doctor.

22. Further automation of instruments and laboratories.Source: TriMark Publications

23. 12-03-2010 19 Point Of Care???

24. POC opens the door for change for the In Vitro Diagnostics & Healthcare. The purpose of point of care testing is the provision of a test result at the most appropriate point in time; enabling a decision on action to be taken that will result in an improved health outcome, without incurring additional costs. There is a need to develop point of care platforms that are able to perform a wide menu of complex in vitro diagnostic tests from minute samples, with the accuracy associated with laboratory systems. Source: TriMark Publications 20

25. POC opens the door for change for the In Vitro Diagnostics & Healthcare. For blood testing, it offers the option of moving some complex immunoassays out of the lab, saving more lives by speeding up the tests needed to detect life-threatening conditions. There is already a trend away from centralised treatment and testing to one which delivers care in a more patient-friendly way. We are convinced that improving point-of-care testing in acute settings in the hospital and at home is in the best interest of patients. Source: TriMark Publications 21

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30. Ease of use (potentially applicable for home testing, GP & specialist office)

31. Multi-analyte (several analytes can be measured simultaneously)

32. Lab-quality sensitivity

34. 27 Philips Future Diagnostics

35. 12-03-2010 28 Thank you Questions?