SlideShare a Scribd company logo
1 of 1
Download to read offline
Visit our science website:
www.fontemscience.com
Since electronic cigarettes (e-cigs) have become popular as alternatives to conventional
cigarettes (CC), with subsequent market growth amongst adult smokers, there is currently
a debate as to whether e-cigs may serve as a gateway to CC smoking or not. Such fears
are related to the possibility that prior use of e-cigs could conceivably result in CC
smoking initiation amongst never smokers. Although the common definition of a “gateway
effect” is based on the concern that current use of a potential low-risk product could
facilitate the use of higher-risk products in the future, there is currently no agreed method
for assessing the so-called “gateway effect” for e-cig products. This creates a lack of
clarity and confusion amongst researchers, politicians, media, vapers and smokers, which
often leads to misleading study interpretations and conclusions being drawn with a
negative impact on policy and regulatory decisions.
To that end, we propose and describe a framework based on product classification to
assess any so-called “gateway effect”: ‘alternative product’, ‘transition product’,
‘substitution product’ or ‘gateway product’.
Each of these four categories corresponds to a different probability of a consumer
switching from a potential low-risk product to a high-risk product, and vice versa, based
on the motives for using them. Using an approach such as dynamic population modelling,
it is possible to classify e-cigs in one of these four product categories and thereby to
assess whether e-cigs are a gateway to or a gateway from CC smoking. Here we
describe this innovative approach.
.
1. Introduction/context
To evaluate the gateway hypothesis for e-cigs, it is necessary to investigate
1) the probabilities to switch from e-cigs to cigarettes consumption
2) The motivation of people to vape and/or to smoke
Considering these two key points, four different product groups can be defined (Figure 1):
substitution products and transition products that are used by consumers who are
motivated to smoke CCs and alternative products and gateway products that are used
by consumers who are not necessary motivated to smoke CCs.
2. Framework definition
The gateway effect is a concept that requires an accurate specific study design and from which data shall be interpreted carefully. The framework proposed here allows
product classification in one out of the four described categories: ‘alternative product’, ‘transition product’, ‘substitution product’ or ‘gateway product’.
Our next step is to define the states and to set up appropriate questionnaires to estimate the probabilities of transitions according to relevant factors (age, gender,
consumption…). In this way, collected data will be used in our computational model in order to estimate the probabilities Pii, Pid and determine the product category.
5. Conclusion
To allocate a product shown in Figure 1, appropriate surveys and specific analytical tools
such as population modelling are required and need to be considered with and without
the presence of e-cigs.
1. Definitions of all the possible states of the base and current case (see figure 2) related
to product consumption have to be established; and the transition probabilities from
moving from one state to another have to be estimated according to relevant individual
characteristics (for example: age, gender, time in the state, quantity of products used).
2. Comprehensive and flexible computational models such Dynamic Population Modelling
(DPM) should be used to model population behaviours using the transition probabilities
estimated above.
Two cases are considered:
• the base-case with three states: NS, “never smoker”; S, “current smoker”; and FS,
“former smoker” and;
• the current case where an e-cig is available on the market.
Additional states include: EU “e-cig user” or DU “dual user”; some states may also
change such as FS to FU “former user” and NS to NU “never user”.
Figure 2 highlights the important transitions (P1, P2, P3 and P4) to consider in order to
allocate a product to a specific category.
3. Framework evaluation
In the state diagrams, the probabilities P1	, P2, P3 and P4 are direct or indirect probabilities
of transition from one state to another. These probabilities can integer multiple
information such as user history (time spent in the different states), consumption levels,
socio-demographic factors (for example: age, education, gender…).
To classify a product according the different probabilities, an indicator P can be evaluated
as follow:
With
P P3 P4 ,	the probability to initiate CC smoking indirectly (via an e-cig)
P P1 P2 , the change of probability to initiate CC smoking directly after the
introduction of e-cig.
Figure 3 shows the product classification according to the probabilities P and P .
4. Product classification
Figure 1. Product classification based on the switching probabilities.
Figure 2. State diagram with
transition probabilities with and
without e-cig on the market .
Figure 3. Product classification
according the probabilities of
transition from one state to
another one.
E-cigarettes: An Assessment of the so-called “Gateway
Effect” based on Product Classification
Thomas Verron1, Xavier Cahours1, Liz Cerson2, Grant O’Connell3 and Stéphane Colard1
1 SEITA-Imperial Brands, 45404 Fleury-les-Aubrais, France; 2 Imperial Tobacco Ltd, 121 Winterstoke Road, Bristol, BS3 2LL, UK; 3 Fontem Ventures B.V., HN Amsterdam 1083, Netherlands
GFN, Warsaw, Poland 17-18 June 2016

More Related Content

Similar to Verron et al 2016

Based on the attached documents, assess CVS’s performance relati.docx
Based on the attached documents, assess CVS’s performance relati.docxBased on the attached documents, assess CVS’s performance relati.docx
Based on the attached documents, assess CVS’s performance relati.docx
JASS44
 
Alight_Statistics_Technical_Report
Alight_Statistics_Technical_ReportAlight_Statistics_Technical_Report
Alight_Statistics_Technical_Report
Peter Zhang
 
Skip Spoerke - Perception Assignment
Skip Spoerke - Perception AssignmentSkip Spoerke - Perception Assignment
Skip Spoerke - Perception Assignment
Skip Spoerke
 
Add a section to the paper you submittedIt is based on the paper (.docx
Add a section to the paper you submittedIt is based on the paper (.docxAdd a section to the paper you submittedIt is based on the paper (.docx
Add a section to the paper you submittedIt is based on the paper (.docx
daniahendric
 
RUnning head ONLINE1ONLINE11Online Shopping Hypo.docx
RUnning head ONLINE1ONLINE11Online Shopping Hypo.docxRUnning head ONLINE1ONLINE11Online Shopping Hypo.docx
RUnning head ONLINE1ONLINE11Online Shopping Hypo.docx
charisellington63520
 
Please with understanding before responding!!!In 500 words I n.docx
Please with understanding before responding!!!In 500 words I n.docxPlease with understanding before responding!!!In 500 words I n.docx
Please with understanding before responding!!!In 500 words I n.docx
LeilaniPoolsy
 

Similar to Verron et al 2016 (20)

How to design the future
How to design the future How to design the future
How to design the future
 
The Digital Trust Paradox: The Key to Product Innovation via Big Data
The Digital Trust Paradox: The Key to Product Innovation via Big DataThe Digital Trust Paradox: The Key to Product Innovation via Big Data
The Digital Trust Paradox: The Key to Product Innovation via Big Data
 
Ps33
Ps33Ps33
Ps33
 
Based on the attached documents, assess CVS’s performance relati.docx
Based on the attached documents, assess CVS’s performance relati.docxBased on the attached documents, assess CVS’s performance relati.docx
Based on the attached documents, assess CVS’s performance relati.docx
 
FINAL THESIS
FINAL THESISFINAL THESIS
FINAL THESIS
 
Palazzolo 2013 (electronic cigarette)
Palazzolo 2013 (electronic cigarette)Palazzolo 2013 (electronic cigarette)
Palazzolo 2013 (electronic cigarette)
 
Alight_Statistics_Technical_Report
Alight_Statistics_Technical_ReportAlight_Statistics_Technical_Report
Alight_Statistics_Technical_Report
 
Telehealthcare Promises And Challenges
Telehealthcare Promises And ChallengesTelehealthcare Promises And Challenges
Telehealthcare Promises And Challenges
 
Skip Spoerke - Perception Assignment
Skip Spoerke - Perception AssignmentSkip Spoerke - Perception Assignment
Skip Spoerke - Perception Assignment
 
10 - Population projections revised, part 1 (2015) (ENG)
10 - Population projections revised, part 1 (2015) (ENG)10 - Population projections revised, part 1 (2015) (ENG)
10 - Population projections revised, part 1 (2015) (ENG)
 
Disabled and elderly assistive technologies
Disabled and elderly assistive technologiesDisabled and elderly assistive technologies
Disabled and elderly assistive technologies
 
Add a section to the paper you submittedIt is based on the paper (.docx
Add a section to the paper you submittedIt is based on the paper (.docxAdd a section to the paper you submittedIt is based on the paper (.docx
Add a section to the paper you submittedIt is based on the paper (.docx
 
EAI - Special Report - Ecigs
EAI  - Special Report - EcigsEAI  - Special Report - Ecigs
EAI - Special Report - Ecigs
 
TheimpactofeWOM-IR1820083229-247.pdf
TheimpactofeWOM-IR1820083229-247.pdfTheimpactofeWOM-IR1820083229-247.pdf
TheimpactofeWOM-IR1820083229-247.pdf
 
RUnning head ONLINE1ONLINE11Online Shopping Hypo.docx
RUnning head ONLINE1ONLINE11Online Shopping Hypo.docxRUnning head ONLINE1ONLINE11Online Shopping Hypo.docx
RUnning head ONLINE1ONLINE11Online Shopping Hypo.docx
 
Please with understanding before responding!!!In 500 words I n.docx
Please with understanding before responding!!!In 500 words I n.docxPlease with understanding before responding!!!In 500 words I n.docx
Please with understanding before responding!!!In 500 words I n.docx
 
UoB Dissertation
UoB DissertationUoB Dissertation
UoB Dissertation
 
nihms799718
nihms799718nihms799718
nihms799718
 
SmokeSignals
SmokeSignalsSmokeSignals
SmokeSignals
 
IRJET- Survey on Facial Feature Detection Methods in Offline Recommendation b...
IRJET- Survey on Facial Feature Detection Methods in Offline Recommendation b...IRJET- Survey on Facial Feature Detection Methods in Offline Recommendation b...
IRJET- Survey on Facial Feature Detection Methods in Offline Recommendation b...
 

More from Fontem Ventures

More from Fontem Ventures (14)

Infographic: Vaping accelerates the decline in the Adult smoking rate in the UK
Infographic: Vaping accelerates the decline in the Adult smoking rate in the UK Infographic: Vaping accelerates the decline in the Adult smoking rate in the UK
Infographic: Vaping accelerates the decline in the Adult smoking rate in the UK
 
Effects of substituting cigarettes with e-cigarettes in adult smokers
Effects of substituting cigarettes with e-cigarettes in adult smokers Effects of substituting cigarettes with e-cigarettes in adult smokers
Effects of substituting cigarettes with e-cigarettes in adult smokers
 
An Assessment of Nicotine Levels on Office Surfaces Before and After Use of E...
An Assessment of Nicotine Levels on Office Surfaces Before and After Use of E...An Assessment of Nicotine Levels on Office Surfaces Before and After Use of E...
An Assessment of Nicotine Levels on Office Surfaces Before and After Use of E...
 
Responsible practice in e vapour products (evp) product stewardship 2016
Responsible practice in e vapour products (evp) product stewardship 2016Responsible practice in e vapour products (evp) product stewardship 2016
Responsible practice in e vapour products (evp) product stewardship 2016
 
Coresta16: Exhaled aerosol properties in a room following use of ecigs
Coresta16: Exhaled aerosol properties in a room following use of ecigsCoresta16: Exhaled aerosol properties in a room following use of ecigs
Coresta16: Exhaled aerosol properties in a room following use of ecigs
 
E-cigarettes and nicotine: What you need to know
E-cigarettes and nicotine: What you need to knowE-cigarettes and nicotine: What you need to know
E-cigarettes and nicotine: What you need to know
 
Are e-cigarettes less harmful than cigarettes?
Are e-cigarettes less harmful than cigarettes?Are e-cigarettes less harmful than cigarettes?
Are e-cigarettes less harmful than cigarettes?
 
Prasauskas et al 2016
Prasauskas et al 2016Prasauskas et al 2016
Prasauskas et al 2016
 
O'connell et al 2016
O'connell et al 2016 O'connell et al 2016
O'connell et al 2016
 
Prasauskas et al 2016
Prasauskas et al 2016 Prasauskas et al 2016
Prasauskas et al 2016
 
Nicotine Retention Following Use of E-Cigarettes
Nicotine Retention Following Use of E-CigarettesNicotine Retention Following Use of E-Cigarettes
Nicotine Retention Following Use of E-Cigarettes
 
Heated Tobacco Products Create Side-Stream Emissions: Implications for Regula...
Heated Tobacco Products Create Side-Stream Emissions: Implications for Regula...Heated Tobacco Products Create Side-Stream Emissions: Implications for Regula...
Heated Tobacco Products Create Side-Stream Emissions: Implications for Regula...
 
An Assessment of Indoor Air Quality before, during and after Unrestricted Use...
An Assessment of Indoor Air Quality before, during and after Unrestricted Use...An Assessment of Indoor Air Quality before, during and after Unrestricted Use...
An Assessment of Indoor Air Quality before, during and after Unrestricted Use...
 
Electronic Cigarettes and Indoor Air Quality: A Simple Approach to Modeling P...
Electronic Cigarettes and Indoor Air Quality: A Simple Approach to Modeling P...Electronic Cigarettes and Indoor Air Quality: A Simple Approach to Modeling P...
Electronic Cigarettes and Indoor Air Quality: A Simple Approach to Modeling P...
 

Recently uploaded

Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
adilkhan87451
 
💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...
💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...
💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...
Sheetaleventcompany
 
Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...
adilkhan87451
 
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
chetankumar9855
 

Recently uploaded (20)

Call Girls Mysore Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Mysore Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Mysore Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Mysore Just Call 8250077686 Top Class Call Girl Service Available
 
9630942363 Genuine Call Girls In Ahmedabad Gujarat Call Girls Service
9630942363 Genuine Call Girls In Ahmedabad Gujarat Call Girls Service9630942363 Genuine Call Girls In Ahmedabad Gujarat Call Girls Service
9630942363 Genuine Call Girls In Ahmedabad Gujarat Call Girls Service
 
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any TimeTop Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
 
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
 
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
 
Saket * Call Girls in Delhi - Phone 9711199012 Escorts Service at 6k to 50k a...
Saket * Call Girls in Delhi - Phone 9711199012 Escorts Service at 6k to 50k a...Saket * Call Girls in Delhi - Phone 9711199012 Escorts Service at 6k to 50k a...
Saket * Call Girls in Delhi - Phone 9711199012 Escorts Service at 6k to 50k a...
 
Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...
Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...
Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...
 
Call Girls Service Jaipur {8445551418} ❤️VVIP BHAWNA Call Girl in Jaipur Raja...
Call Girls Service Jaipur {8445551418} ❤️VVIP BHAWNA Call Girl in Jaipur Raja...Call Girls Service Jaipur {8445551418} ❤️VVIP BHAWNA Call Girl in Jaipur Raja...
Call Girls Service Jaipur {8445551418} ❤️VVIP BHAWNA Call Girl in Jaipur Raja...
 
Andheri East ^ (Genuine) Escort Service Mumbai ₹7.5k Pick Up & Drop With Cash...
Andheri East ^ (Genuine) Escort Service Mumbai ₹7.5k Pick Up & Drop With Cash...Andheri East ^ (Genuine) Escort Service Mumbai ₹7.5k Pick Up & Drop With Cash...
Andheri East ^ (Genuine) Escort Service Mumbai ₹7.5k Pick Up & Drop With Cash...
 
Call Girls Ahmedabad Just Call 9630942363 Top Class Call Girl Service Available
Call Girls Ahmedabad Just Call 9630942363 Top Class Call Girl Service AvailableCall Girls Ahmedabad Just Call 9630942363 Top Class Call Girl Service Available
Call Girls Ahmedabad Just Call 9630942363 Top Class Call Girl Service Available
 
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
 
💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...
💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...
💚Call Girls In Amritsar 💯Anvi 📲🔝8725944379🔝Amritsar Call Girl No💰Advance Cash...
 
Top Rated Call Girls Kerala ☎ 8250092165👄 Delivery in 20 Mins Near Me
Top Rated Call Girls Kerala ☎ 8250092165👄 Delivery in 20 Mins Near MeTop Rated Call Girls Kerala ☎ 8250092165👄 Delivery in 20 Mins Near Me
Top Rated Call Girls Kerala ☎ 8250092165👄 Delivery in 20 Mins Near Me
 
Call Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls Mumbai Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Mumbai Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Mumbai Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Mumbai Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls Amritsar Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Amritsar Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Amritsar Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Amritsar Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service Avai...
 
💕SONAM KUMAR💕Premium Call Girls Jaipur ↘️9257276172 ↙️One Night Stand With Lo...
💕SONAM KUMAR💕Premium Call Girls Jaipur ↘️9257276172 ↙️One Night Stand With Lo...💕SONAM KUMAR💕Premium Call Girls Jaipur ↘️9257276172 ↙️One Night Stand With Lo...
💕SONAM KUMAR💕Premium Call Girls Jaipur ↘️9257276172 ↙️One Night Stand With Lo...
 
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
Call Girl In Pune 👉 Just CALL ME: 9352988975 💋 Call Out Call Both With High p...
 
8980367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad
8980367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad8980367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad
8980367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad
 

Verron et al 2016

  • 1. Visit our science website: www.fontemscience.com Since electronic cigarettes (e-cigs) have become popular as alternatives to conventional cigarettes (CC), with subsequent market growth amongst adult smokers, there is currently a debate as to whether e-cigs may serve as a gateway to CC smoking or not. Such fears are related to the possibility that prior use of e-cigs could conceivably result in CC smoking initiation amongst never smokers. Although the common definition of a “gateway effect” is based on the concern that current use of a potential low-risk product could facilitate the use of higher-risk products in the future, there is currently no agreed method for assessing the so-called “gateway effect” for e-cig products. This creates a lack of clarity and confusion amongst researchers, politicians, media, vapers and smokers, which often leads to misleading study interpretations and conclusions being drawn with a negative impact on policy and regulatory decisions. To that end, we propose and describe a framework based on product classification to assess any so-called “gateway effect”: ‘alternative product’, ‘transition product’, ‘substitution product’ or ‘gateway product’. Each of these four categories corresponds to a different probability of a consumer switching from a potential low-risk product to a high-risk product, and vice versa, based on the motives for using them. Using an approach such as dynamic population modelling, it is possible to classify e-cigs in one of these four product categories and thereby to assess whether e-cigs are a gateway to or a gateway from CC smoking. Here we describe this innovative approach. . 1. Introduction/context To evaluate the gateway hypothesis for e-cigs, it is necessary to investigate 1) the probabilities to switch from e-cigs to cigarettes consumption 2) The motivation of people to vape and/or to smoke Considering these two key points, four different product groups can be defined (Figure 1): substitution products and transition products that are used by consumers who are motivated to smoke CCs and alternative products and gateway products that are used by consumers who are not necessary motivated to smoke CCs. 2. Framework definition The gateway effect is a concept that requires an accurate specific study design and from which data shall be interpreted carefully. The framework proposed here allows product classification in one out of the four described categories: ‘alternative product’, ‘transition product’, ‘substitution product’ or ‘gateway product’. Our next step is to define the states and to set up appropriate questionnaires to estimate the probabilities of transitions according to relevant factors (age, gender, consumption…). In this way, collected data will be used in our computational model in order to estimate the probabilities Pii, Pid and determine the product category. 5. Conclusion To allocate a product shown in Figure 1, appropriate surveys and specific analytical tools such as population modelling are required and need to be considered with and without the presence of e-cigs. 1. Definitions of all the possible states of the base and current case (see figure 2) related to product consumption have to be established; and the transition probabilities from moving from one state to another have to be estimated according to relevant individual characteristics (for example: age, gender, time in the state, quantity of products used). 2. Comprehensive and flexible computational models such Dynamic Population Modelling (DPM) should be used to model population behaviours using the transition probabilities estimated above. Two cases are considered: • the base-case with three states: NS, “never smoker”; S, “current smoker”; and FS, “former smoker” and; • the current case where an e-cig is available on the market. Additional states include: EU “e-cig user” or DU “dual user”; some states may also change such as FS to FU “former user” and NS to NU “never user”. Figure 2 highlights the important transitions (P1, P2, P3 and P4) to consider in order to allocate a product to a specific category. 3. Framework evaluation In the state diagrams, the probabilities P1 , P2, P3 and P4 are direct or indirect probabilities of transition from one state to another. These probabilities can integer multiple information such as user history (time spent in the different states), consumption levels, socio-demographic factors (for example: age, education, gender…). To classify a product according the different probabilities, an indicator P can be evaluated as follow: With P P3 P4 , the probability to initiate CC smoking indirectly (via an e-cig) P P1 P2 , the change of probability to initiate CC smoking directly after the introduction of e-cig. Figure 3 shows the product classification according to the probabilities P and P . 4. Product classification Figure 1. Product classification based on the switching probabilities. Figure 2. State diagram with transition probabilities with and without e-cig on the market . Figure 3. Product classification according the probabilities of transition from one state to another one. E-cigarettes: An Assessment of the so-called “Gateway Effect” based on Product Classification Thomas Verron1, Xavier Cahours1, Liz Cerson2, Grant O’Connell3 and Stéphane Colard1 1 SEITA-Imperial Brands, 45404 Fleury-les-Aubrais, France; 2 Imperial Tobacco Ltd, 121 Winterstoke Road, Bristol, BS3 2LL, UK; 3 Fontem Ventures B.V., HN Amsterdam 1083, Netherlands GFN, Warsaw, Poland 17-18 June 2016